ANTI-HUMAN MIP-1ALPHA Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project
(www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these
protocols and other useful information about Prestige Antibodies and the HPA, visit .
Allgemeine Beschreibung
Mitogen-activated protein kinase associated protein 1 (MAPKAP1 )/stress-activated protein kinase-interacting protein 1 (SIN1) is an essential subunit of the mammalian target of rapamycin complex 2 (mTORC2) complex.
Biochem/physiol Actions
Mitogen-activated protein kinase associated protein 1 (MAPKAP1 )/stress-activated protein kinase-interacting protein 1 (SIN1) regulates cell survival and cytoskeletal organization. It maintains mammalian target of rapamycin complex 2 (mTORC2) integrity and modulates Akt phosphorylation. Knockdown of SIN1 results in the disruption of the rictor-mTOR interaction and in defective Akt-Ser473 phosphorylation.
ANTI-HUMAN MIP-1ALPHA Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
