L371,257

162042-44-6

CAS-Nr.: 162042-44-6

Englisch Name:: L371,257

Synonyma:: 257;L-371;L371,257;L371,257,L 371,257;1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one;1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine;2H-3,1-Benzoxazin-2-one, 1-[1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-piperidinyl]-1,4-dihydro-;1-(1-(4-((1-acetylpiperidin-4-yl)oxy)-2-methoxybenzoyl)piperidin-4-yl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one

CBNumber:: CB8850593

Summenformel:: C28H33N3O6

Molgewicht:: 507.58

MOL-Datei:: 162042-44-6.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 59

L371,257 Eigenschaften

Siedepunkt:: 728.9±60.0 °C(Predicted)

Dichte: 1.282±0.06 g/cm3(Predicted)

storage temp.: Store at RT

L?slichkeit: Soluble to 10 mM in DMSO with gentle warming

Aggregatzustand: Powder

pka: 0.73±0.20(Predicted)

Farbe: White to off-white

Sicherheit

WGK Germany	WGK 3
Speicherklasse	11 - Combustible Solids

L371,257 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

L-371,257 is a potent antagonist of oxytocin-induced contractions of the rat uterus in vitro and in vivo and has significant oral bioavailability in rats.

Biologische Aktivit?t

Potent, high affinity human oxytocin (OT) receptor antagonist (K i = 4.6 nM) that displays > 800-fold selectivity over human arginine vasopressin receptors V 1a and V 2 . Antagonizes oxytocin-induced contractions in isolated rat uterine tissue (pA 2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Orally active.

L371,257 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

L371,257 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 59)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3135	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4849	55
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Shanghai YuanYe Biotechnology Co., Ltd.	13636370518	shyysw007@163.com	China	89686	60
Shanghai Rechem science Co., Ltd.	021-31433387 15618786686	sales@rechemscience.com	China	2981	58

162042-44-6()Verwandte Suche:

1-Benzyl-N-phenylpiperidin-4-amin 2,4-Dihydroxybenzamid

L371,257
1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine
1-[1-[4-(1-acetylpiperidin-4-yl)oxy-2-methoxybenzoyl]piperidin-4-yl]-4H-3,1-benzoxazin-2-one
2H-3,1-Benzoxazin-2-one, 1-[1-[4-[(1-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-piperidinyl]-1,4-dihydro-
257
L-371
L371,257,L 371,257
1-(1-(4-((1-acetylpiperidin-4-yl)oxy)-2-methoxybenzoyl)piperidin-4-yl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one
162042-44-6
C28H33N3O6

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