Alimadol Chemische Eigenschaften,Einsatz,Produktion Methoden

Originator

Alimadol ,ZYF Pharm Chemical

Manufacturing Process

12 g 3,3-diphenyl-3-methoxypropylamine, 13.5 g trifluoroacetic acid anhydride, 6.0 g pyridine and 100 ml benzene was heated by stirring for 1 hour at 40°C. Then in was cooled to 0°C and poured in water. The organic layer was separated, washed with diluted HCl and water, and evaporated to dryness. The residue N-(3,3-diphenyl-3-methoxypropyl)trifluoroacetamide melted at 108°-110°C. Yield: 98%.
8 g above amide was in 80 ml hexamethyl phosphoric acid amide dissolved mixed with 1.7 g sodium hydride and stirred for 3 hours. Then 5.7 g allyl bromide was added dropwise and the mixture was stirred for 30 minutes. It was diluted with water and extracted with benzene. Benzene layer was separated, evaporated to dryness. The residue was mixed with 100 ml of 75% ethanol and 1 g sodium hydroxide and heated for 1 hour. Ethanol was distilled off and reaction product was extracted with ether. Yield of N-(3-methoxy-3,3- diphenylpropyl)allylamin (or 1,1-diphenyl-1-methoxy-3-allylaminopropane) was 6.5 g (97%). MP: 40°-50°C. Hydrochloride melted at 137°-138°C.

Therapeutic Function

Analgesic

Alimadol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Alimadol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
TargetMol Chemicals Inc.	+17819995354	marketing@targetmol.com	United States	19956	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29867	58

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• Alimadol
• 3-Methoxy-3,3-diphenyl-N-(2-propenyl)-1-propanamine
• 1,1-diphenyl-1-methoxy-3-allylaminopropane
• 3-methoxy-3,3-diphenyl-N-prop-2-enylpropan-1-amine
• Benzenepropanamine, γ-methoxy-γ-phenyl-N-2-propen-1-yl-
• A 4020
• A4020
• A-4020
• 52742-40-2