Flibanserin
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- CAS-Nr.
- 167933-07-5
- Englisch Name:
- Flibanserin
- Synonyma:
- Filbanserin;Flibanserine;BIMT;Niemunerkeine;1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one;Girosa;Bimt 17;BIMT 17BS;Fbanselin;Flibanerins
- CBNumber:
- CB91178756
- Summenformel:
- C20H21F3N4O
- Molgewicht:
- 390.4
- MOL-Datei:
- 167933-07-5.mol
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Flibanserin Eigenschaften
- Dichte
- 1.292±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: soluble10mg/mL, clear
- Aggregatzustand
- powder
- pka
- 12.12±0.30(Predicted)
- Farbe
- white to beige
- InChI
- InChI=1S/C20H21F3N4O/c21-20(22,23)15-4-3-5-16(14-15)26-11-8-25(9-12-26)10-13-27-18-7-2-1-6-17(18)24-19(27)28/h1-7,14H,8-13H2,(H,24,28)
- InChIKey
- PPRRDFIXUUSXRA-UHFFFAOYSA-N
- SMILES
- C1(=O)N(CCN2CCN(C3=CC=CC(C(F)(F)F)=C3)CC2)C2=CC=CC=C2N1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
T |
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| R-S?tze: |
25-36/37/38 |
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| S-S?tze: |
26-45 |
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| RIDADR |
UN 2811 6.1 / PGIII |
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| WGK Germany |
3 |
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| Speicherklasse |
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects |
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| Hazard Classifications |
Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
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| Giftige Stoffe Daten |
167933-07-5(Hazardous Substances Data) |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H301 |
Giftig bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 3 |
Achtung |
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P264, P270, P301+P310, P321, P330,P405, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P302+P352 |
BEI BERüHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckm??ig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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Flibanserin Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Flibanserin is a drug originally
developed by Boehringer-Ingelheim and later Sprout Pharmaceuticals, which was approved in 2015 by the FDA for the
treatment of premenopausal women with hypoactive sexual
desire disorder (HSDD). The drug, which was originally
developed for the treatment of depression by Boehringer-
Ingelheim, is a full agonist of the 5-HT1A receptor, an
antagonist of the 5-HT2A receptor, and a partial agonist of
the dopamine-4 (D4) receptor, which triggers increased
dopamine and norepinephrine levels along with decreased
serotonin levels. In three randomized trials
involving 2400 premenopausal women, the drug was found
to increase the number of satisfying sexual events by 0.5-1.0
events per month and increased sexual desire on average by
10-12% over placebo. Side effects include decreased blood
pressure and loss of consciousness, especially in subjects who
consumed alcohol.
Verwenden
Antidepressant (5-HT1a agonist and 5-HT2 antagonist).
Flibanserin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Flibanserin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 364)Lieferanten
167933-07-5()Verwandte Suche:
- Flibanserin,Bimt 17, Bimt-17-BS,Girosa
- Flibanserin
- Bimt 17
- 3-[2-[4-[4-(Trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one
- Flibanerins
- BIMT 17BS
- 2H-Benzimidazol-2-one,1,3-dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-
- Flibanserin(BIMT17)
- 3-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-1H-benzimidazol-2-one
- Flibaneserin
- BIMT-17;BIMT-17BS
- Flubensin (female)
- Flibaserin(female)
- Fbanselin
- Flubanserin
- crystal paracetamol Flibanserin CAS NO.167933-07-5
- Girosa
- Color Lin fluorine class
- Flibanserin USP/EP/BP
- Flibaserin USP/EP/BP
- 2-Flibanserin
- Flibanserin ADDYI
- Flibanserin powder
- 1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one
- Niemunerkeine
- Flibanserine
- BIMT
- 1-(2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)ethyl)-1H-benzo[d]imidazol-2(3H)-one
- Flibanserin 100mg Tablets
- Flibanserin, 10 mM in DMSO
- Flibanserin 98%
- Filbanserin
- 167933-07-5
- C20H21F3N4O
- C20H21N4F3O
- API
- API,chemical material
- 1
