Alarelin Acetate
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- CAS-Nr.
- 79561-22-1
- Englisch Name:
- Alarelin Acetate
- Synonyma:
- ALARELIN;Alarelin Acetate;Allah Lin;pGlu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt;(DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING FACTOR (SEA BREAM);SURFAGON;Alareline Acetate;Alarelin impurity;Alarelin USP/EP/BP;Alarelin DiAcetate
- CBNumber:
- CB9119598
- Summenformel:
- C58H82N16O14
- Molgewicht:
- 1227.39
- MOL-Datei:
- 79561-22-1.mol
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Alarelin Acetate Eigenschaften
- storage temp.
- −20°C
- L?slichkeit
- ≥128.7 mg/mL in DMSO; ≥128.6 mg/mL in EtOH; ≥128.8 mg/mL in H2O
- Aggregatzustand
- powder
- Farbe
- White to off-white
- Sequenz
- Glu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt
- InChIKey
- IMRONVSKLHSCMF-VWCBMNBRNA-N
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
T |
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| R-S?tze: |
60 |
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| S-S?tze: |
53-45 |
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| WGK Germany |
3 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H360 |
Kann die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. |
Fertility (Fruchtbarkeit) |
Kategorie 1 |
Achtung |
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Alarelin Acetate Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R60:Kann die Fortpflanzungsf?higkeit beeintr?chtigen.
S-S?tze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Cytotoxicity
Cell Assay
The cells are trypsinized in a solution of 2.5 g/L trypsin and seeded in a 96-well plate. After the cells are grown for 24 h to approximately 800 g/L subconfluent state, 0.1 mL medium containing 2.5% calf serum and various concentrations (0.001, 0.1, 10 μM) of alarelin is added to each well, respectively, and incubated for 24 h in a CO2 incubator. Each concentration is tested in at least 12 wells. Briefly, 15 μL of MTT solution is added to each well and incubated for 4 h. Then, the medium and MTT are removed and 150 μL of DMSO is added to each well and shaken for 10 min to dissolve the crystal. The OD is determined at 490 nm using an ELISA reader.
Animal Administration
Rats: Male Sprague-Dawley rats are divided into two groups. In Group I: Gastric acid secretion is measured in a chambered stomach. Briefly, the abdomen is incised, and both the stomach and duodemun are exposed and tied respectively; then 1.5 mL 0.9% sodium chloride (containing Alarelin, 2 μg/kg) is infused into the each chambered stomach. After 15, 30, 45, 60 min, the gastric juice is drew out of the chambered stomach and the pH is measured in the ABL-500 respectively. The control is infused saline instead of Alarelin. In Group II: After anaesthetized, 2 mL Alarelin (2 μg/kg) is administered into the tail vein. The control is injected the saline instead of Alarelin. Then, the stomach and duodenum are tied and infused 1.5 mL saline immediately. After 15, 30, 45, 60 min, the gastric juice is also drew out of the chambered stomach and the pH is measured in the ABL-500 respectively.
Alarelin Acetate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Alarelin Acetate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 355)Lieferanten
79561-22-1()Verwandte Suche:
- [des-Gly10, D-Ala6]-LH-RH ethylamide hydrate acetate salt
- Amp:Adenosine-5-MonophosphateFreeAcid
- HO-Glp-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHCH2CH3
- Alareline Acetate
- 6-D-Ala-10-D-gly-LHRH-ethylaMide
- DES-GLY10,[D-ALA6]-LH-RH ETHYLAMIDE ACETATE SALT
- (DES-GLY10,D-ALA6,PRO-NHET9)-LHRH
- PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-NHET
- (DES-GLY10,D-ALA6,PRO-NHET9)-GONADOTROPIN-RELEASING HORMONE (SEA BREAM)
- (DES-GLY10,D-ALA6,PRO-NHET9)-GONADOTROPIN-RELEASING HORMONE
- (DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING FACTOR
- (DES-GLY10,D-ALA6,PRO-NHET9)-LHRH (SEA BREAM)
- [DES-GLY10, D-ALA6, PRO-NHET9]-LH-RH (HUMAN)
- (DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING HORMONE
- (DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING HORMONE (SEA BREAM)
- [DES-GLY10, D-ALA6, PRO-NHET9]-LUTEINIZING HORMONE-RELEASING HORMONE (HUMAN)
- [DALA6,DES-GLY10] LUTEINIZING HORMONE-RELEASING HORMONE, ETHYL AMIDE
- [D-ALA6,DES-GLY10]-LH-RH ETHYLAMIDE
- GLP-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-NHET
- SURFAGON
- PGLU-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-NHET ACETATE SALT
- N-[1-[[1-[[1-[[1-[1-[[1-[[1-[2-(ETHYLCARBAMOYL)PYRROLIDIN-1-YL]CARBONYL-4-GUANIDINO-BUTYL]CARBAMOYL]-3-METHYL-BUTYL]CARBAMOYL]ETHYLCARBAMOYL]-2-(4-HYDROXYPHENYL)-ETHYL]CARBAMOYL]-2-HYDROXY-ETHYL]CARBAMOYL]-2-(1H-INDOL-3-YL)ETHYL]CARBAMOYL]-2-(3H-IMIDAZOL-4-YL)ETHYL]-5-OXO-PYRROLIDINE-2-CARBOXAMIDE
- des-gly10(D-ala6) luteinizing hormone*releasing H
- (DES-GLY10 D-ALA6)-LH-RH ETHYLAMIDE ACE
- LHRH, Ala(6)-Gly(10)-ethylamide-
- Alarelin impurity
- Alarelin USP/EP/BP
- Alarelin AcetateQ: What is
Alarelin Acetate Q: What is the CAS Number of
Alarelin Acetate Q: What is the storage condition of
Alarelin Acetate
- Alarelin CAS79561-22-1
- N-[1-[[1-[[1-[[1-[[1-[[1-[[5-(diaminomethylideneamino)-1-[2-(ethylcarbamoyl)-1-pyrrolidinyl]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-(4-hydroxyp
- Alarelin DiAcetate
- (DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING FACTOR (SEA BREAM)
- Alarelin Acetate
- Alarelin acetate salt
- Alarelin Acetate, 10 mM in DMSO
- Alarelin Acetate - Bio-X ?
- Allah Lin
- ALARELIN
- pGlu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt
- 79561-22-1
- C56H78N16O12
- C60H86N16O16
- C56H78N16O122C2H4O2
- Peptides
- Releasing Factors
- LH-RH
- Amino Acids and Peptides
- Biochemicals and Reagents
- BioChemical
- API
- Peptide
- LH-RH
- LH-RHPeptides for Cell Biology
- Neuropeptides
- Releasing Factors
- Amino Acid Derivatives
- 79561-22-1
