Ethyl 5-Bromoindole-2-carboxylate
|
|
|
- CAS-Nr.
- 16732-70-0
- Englisch Name:
- Ethyl 5-Bromoindole-2-carboxylate
- Synonyma:
- ETHYL 5-BROMO-1H-INDOLE-2-CARBOXYLATE;5-Br-ICA-OEt;5-BROMO-2-CARBETHOXYINDOLE;5-BROMO-2-INDOLECARBOXYLIC;Ethyl-5-Bromo -2-carboxy late;6-Mercapto-2,4-dimethyl-anisol;-Ethyl bromoindole-2-carboxylate;Ethy 5-Bromoindole-2-carboxylate;ETHYL 5-BROMOINDOLE-2-CARBOXYLATE;2-(Ethoxycarbonyl)-5-bromo-indole
- CBNumber:
- CB9128190
- Summenformel:
- C11H10BrNO2
- Molgewicht:
- 268.11
- MOL-Datei:
- 16732-70-0.mol
|
Ethyl 5-Bromoindole-2-carboxylate Eigenschaften
- Schmelzpunkt:
- 165 °C
- Siedepunkt:
- 394.7±22.0 °C(Predicted)
- Dichte
- 1.554±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- soluble in Acetone
- pka
- 14.05±0.30(Predicted)
- Aggregatzustand
- Solid
- Farbe
- White to Orange to Green
- InChI
- InChI=1S/C11H10BrNO2/c1-2-15-11(14)10-6-7-5-8(12)3-4-9(7)13-10/h3-6,13H,2H2,1H3
- InChIKey
- LWRLKENDQISGEU-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(Br)C=C2)C=C1C(OCC)=O
- CAS Datenbank
- 16732-70-0(CAS DataBase Reference)
Ethyl 5-Bromoindole-2-carboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Ethyl 5-Bromoindole-2-carboxylate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Hazard
Ethyl 5-Bromoindole-2-carboxylate causes skin irritation and serious eye irritation.
Chemische Eigenschaften
Ethyl 5-Bromoindole-2-carboxylate is stable under normal conditions, it reacts with oxidizing agents.
Synthese
The preparation of Ethyl 5-Bromoindole-2-carboxylate was as follows: A 25 mL Schlenk reaction tube was used, and 69 mg of p-bromoaniline, 9 mg of palladium acetate, and 80 mg of molecular sieve were added. Then, 93 mg of ethyl 2-oxopropionate, 96 mg of acetic acid, and 2 mL of dimethyl sulfoxide were injected. A 200 mL oxygen bulb was attached, and the mixture was stirred at 70 °C for 18 hours using a chemical book. After the reaction was complete, 15 mL of ethyl acetate was added to dilute the reaction solution. The mixture was filtered, washed twice with 10 mL of brine, and the organic phase was separated. The aqueous phase was extracted once with ethyl acetate. The organic phases were combined, and column chromatography was used to separate the target product, yielding 50 mg of pure ethyl 5-bromoindole-2-carboxylate (47% yield).
Ethyl 5-Bromoindole-2-carboxylate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Ethyl 5-Bromoindole-2-carboxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 401)Lieferanten
16732-70-0()Verwandte Suche:
- 2-(Ethoxycarbonyl)-5-bromo-indole
- 1H-INDOLE-2-CARBOXYLIC ACID, 5-BROMO-, ETHYL ESTER
- 5-BROMOINDOLE-2-CARBOXYLIC ACID ETHYL ESTER
- 5-BROMO-1H-INDOLE-2-CARBOXYLIC ACID ETHYL ESTER
- 5-BROMO-2-CARBETHOXYINDOLE
- 5-BROMO-2-INDOLECARBOXYLIC ACID ETHYL ESTER
- ETHYL 5-BROMOINDOLE-2-CARBOXYLATE
- 5-BROMO-2-INDOLECARBOXYLIC
- 5-Br-ICA-OEt
- Ethyl-5-Bromo -2-carboxy late
- 5-Bromo-2-(ethoxycarbonyl)-1H-indole
- 5-BroMoindole-2-carboxylic acid ethy
- 6-Mercapto-2,4-dimethyl-anisol
- Ethyl5-Bromoindole-2-carboxylate>
- Ethyl 5-bromo-1H-indol-2-carboxylate
- -Ethyl bromoindole-2-carboxylate
- Ethy 5-Bromoindole-2-carboxylate
- ETHYL 5-BROMO-1H-INDOLE-2-CARBOXYLATE
- 16732-70-0
- 16732-70-1
- C11H10NO2Br
- Indoles
- Simple Indoles
- Pharmaceutical Intermediates
- Heterocycles series
- Indole/indoline/oxindole
- Indole and Indoline
- Indoles and derivatives
- Indole
- Organic acids
- 1
