Isoliquiritigenin
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- CAS-Nr.
- 961-29-5
- Englisch Name:
- Isoliquiritigenin
- Synonyma:
- ISL;ISOLIQUIRTIGENIN;4,2',4'-TRIHYDROXYCHALCONE;(2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one;gu17;Isoliquiritigen;Isqliquiritigenin;ISOLIQUIRITIGENIN;ISOLIQUIRITIGENIN(P);Isoliquiritigenin>
- CBNumber:
- CB9131280
- Summenformel:
- C15H12O4
- Molgewicht:
- 256.25
- MOL-Datei:
- 961-29-5.mol
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Isoliquiritigenin Eigenschaften
- Schmelzpunkt:
- 206-210°C
- Siedepunkt:
- 504.0±42.0 °C(Predicted)
- Dichte
- 1.384±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- H2O: <0.1 mg/mL
- pka
- 7.50±0.35(Predicted)
- Aggregatzustand
- powder
- Farbe
- yellow to orange
- Wasserl?slichkeit
- H2O: <0.1mg/mL
methanol: 10mg/mL
DMSO: 20mg/mL
- Sensitive
- Light Sensitive & Hygroscopic
- BRN
- 1914296
- Kosmetik-Inhaltsstoffe Funktionen
- SKIN CONDITIONING - EMOLLIENT
- InChI
- InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+
- InChIKey
- DXDRHHKMWQZJHT-FPYGCLRLSA-N
- SMILES
- C(C1=CC=C(O)C=C1O)(=O)/C=C/C1=CC=C(O)C=C1
- LogP
- 3.110 (est)
- CAS Datenbank
- 961-29-5(CAS DataBase Reference)
Isoliquiritigenin Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
It is a yellow crystalline powder soluble in organic solvents such as methanol, ethanol, and DMSO, and is derived from liquorice and dianthus.
Allgemeine Beschreibung
Isoliquiritigenin is an aromatic ketone and belongs to the chalcone group of compound. It is derived from licorice and is a component in medicine and food.
Anticancer Research
It is extracted from Dipteryx odorata seeds, found to be active in induction of quininereductase, and thus prevents chemical carcinogenesis. In a dose- and time-dependentmanner, it significantly inhibits the proliferation of prostate cancer cells,and this isoliquiritigenin-induced cell cycle arrest and antiproliferative effects maybe manifested by growth arrest- and DNA damage-inducible gene 153 (GADD153).It induces apoptosis in prostate cancer cells through mitochondrial apoptosispathway in which mitochondrial membrane potential is disrupted, cytochrome-cand Smac/Diablo are released, and caspase-9 is activated. It is reported to enhancethe expression of universal inhibitor of cyclin-dependent kinases, p21CIP1/WAF1, in adose- and time-dependent manner in A549 human lung cancer cells (Kanazawaet al. 2003; Ii et al. 2004; Balunas and Kinghorn 2005; Jung et al. 2006).
Isoliquiritigenin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Isoliquiritigenin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 447)Lieferanten
961-29-5()Verwandte Suche:
Glycyrrhizine(R19,R21) 10-20%,13-20% HPLC
Tetraphenylcyclopentadienon
LIQUIRITIGENIN
Glycyrrhizinsure
2,2',4,4'-Tetrahydroxybenzophenon
1-Phenyl-2-nitropropene
DGL
Benzil
3,4-Dihydroxyacetophenone
4'-Hydroxyacetophenon
Kaliumdihydrogenorthophosphat
Ifosfamid
Rutosid
Diosmin
1-[4-[[6-O-(6-Desoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)prop-2-en-1-on
5,7-Dihydroxy-2-(3,4,5-trimethoxyphenyl)-4-benzopyron
(E)-2',4,4'-Trihydroxy-3-methoxychalkon
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyron
- gu17
- Isqliquiritigenin
- ISOLIQUIRTEGENIN (2',4,4'-TRIHYDROXYCHAL
- ISOLIQUIRITIGENIN(P)
- ISOLIQUIRITIGENIN(RG)
- (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one, 4,2μ,4μ-Trihydroxychalcone
- Isoliquiritigenin，4,2',4'-Trihydroxychalcone
- (E)-2',4,4'-Trihydroxychalcone
- 2',4,4'-Trihydroxy-trans-chalcone
- 2’,4,4’-trihydroxy-chalcon
- 4,4’-trihydroxychalcone(e)-2
- 4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-1-((e)-2-propen-1-on
- (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
2',4,4'-Trihydroxychalcone
- Isoliquiritigenin, >=98%
- (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
- Isoliquiritigenin
(E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
- 2',4',4-TRIHYDROXYCHALCONE
- ISOLIQUIRITIGENIN
- (e)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
- Isoliquiritigenin 961-29-5
- Isoliquiritigen
- Isoliquiritigenin>
- Isoliquiritigenin Standard
- 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-
- Isoliquiritigenin USP/EP/BP
- Isoliquiritigenin (GU17)
- TIANFUCHEM--961-29-5--Isoliquiritigenin
- Isoliquiritigenin Glycyrrhiza extract
- Isoliquiritigenin
CAS
- Isoliquiritigenin-RM
- Isoliquiritigenin, natural
- Isoliquiritigenin, 10 mM in DMSO
- (E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propylene-1-one
- High quality Isoliquiritigenin
- (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one
- 4,2',4'-TRIHYDROXYCHALCONE
- ISL
- ISOLIQUIRTIGENIN
- 961-29-5
- BioChemical
- Cell Biology
- Cell Signaling and Neuroscience
- Cyclic Nucleotide Metabolism
- G Proteins and Cyclic Nucleotides
- Guanylyl Cyclase Activators
- The group of Liquorice
- sy
- Aromatics
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Chalcones
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Inhibitors
