4,5-DIHYDRO-N-[4-[[4-(1-METHYLETHOXY)PHENYL]CARBONYL]PHENYL]-1H-IMIDAZOL-2-AMINE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Recently, a series of relatively simple compounds were found to be high-affinity ligands and functional antagonists for the human IP (prostacyclin) receptor. CAY10449 is one of the more potent of these. CAY10449 antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Likewise, it inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a K_i value of about 3 nM. Although CAY10449 was not tested in rats, the related compound CAY10441 shows significant analgesic activity in standard antinociceptive assays.

4,5-DIHYDRO-N-[4-[[4-(1-METHYLETHOXY)PHENYL]CARBONYL]PHENYL]-1H-IMIDAZOL-2-AMINE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4,5-DIHYDRO-N-[4-[[4-(1-METHYLETHOXY)PHENYL]CARBONYL]PHENYL]-1H-IMIDAZOL-2-AMINE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19853	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Cayman Chemical Company	--	sales@caymanchem.com	China	6838	58
Santa Cruz Biotechnology Inc	--	scbt@scbt.com	China	6594	58

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• 4,5-DIHYDRO-N-[4-[[4-(1-METHYLETHOXY)PHENYL]CARBONYL]PHENYL]-1H-IMIDAZOL-2-AMINE
• CAY10449