一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

1H-indazole-7-carboxylic acid

1H-indazole-7-carboxylic acid Struktur
677304-69-7
CAS-Nr.
677304-69-7
Englisch Name:
1H-indazole-7-carboxylic acid
Synonyma:
7-Carboxy-1H-indazole;CgH6N2O2;Niraparib Intermediate4;7-INDAZOLE CARBOXYLIC ACID;7-INDAZOLE CARBOXYLLIC ACID;1H-Indazole-7-carboxylic aid;1H-Indazol-7-carboxylic acid;1H-INDAZOLE-7-CARBOXYLIC ACID;7-(1H)Indazole carboxylic acid;1H-Indazole-7-carboxylic acid
CBNumber:
CB9197275
Summenformel:
C8H6N2O2
Molgewicht:
162.15
MOL-Datei:
677304-69-7.mol

1H-indazole-7-carboxylic acid Eigenschaften

Schmelzpunkt:
ca 240℃
Siedepunkt:
443.7±18.0 °C(Predicted)
Dichte
1.506±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
pka
3.71±0.10(Predicted)
Aggregatzustand
Crystalline Powder
Farbe
White to yellow
InChI
InChI=1S/C8H6N2O2/c11-8(12)6-3-1-2-5-4-9-10-7(5)6/h1-4H,(H,9,10)(H,11,12)
InChIKey
WBCWIQCXHSXMDH-UHFFFAOYSA-N
SMILES
N1C2=C(C=CC=C2C(O)=O)C=N1
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
WGK Germany  WGK 3
HS Code  29339980
Speicherklasse 11 - Combustible Solids
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

1H-indazole-7-carboxylic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

1H-indazole-7-carboxylic Acid is an inhibitor of nitric oxide synthases.

synthetische

Synthesis of 1H-indazole-7-carboxylic acid, H2L4: To 60 mL anhydrous toluene under a nitrogen atmosphere was added methyl-2-amino-3-methylbenzoate (1.8 g, 11 mmol) and KOAc (560 mg, 5.7 mmol), and the mixture heated to reflux, at which time acetic anhydride (3.2 mL, 34 mmol) was added and the mixture stirred at reflux for 10 min. Isoamyl nitrite (2.3 mL, 18 mmol) was added over 30 min and the mixture refluxed overnight. On cooling, the mixture was filtered and evaporated to dryness to give 1.6 g of a pale brown solid, which analysed for methyl 1H-indazole-7-carboxylate. This material was taken up in 40 mL THF, added to a solution of LiOH (5 g, 210 mmol) in 40 mL water, and heated at reflux for 48 h. On cooling, the mixture was concentrated on a rotary evaporator and the resulting aqueous phase filtered and adjusted to pH 4 with dilute HCl, to precipitate the product, which was filtered, washed with water and dried under vacuum. Yield 810 mg, 45%; mp 218–222 °C (decomp);
δH (500 MHz, d6-DMSO): 7.23 (t, 1H, J = 7.5 Hz, H4 ), 7.97 (dd, 1H, J = 7.5, 1.0 Hz, H3 ), 8.06 (dd, 1H, J = 7.8, 0.8 Hz, H5 ), 8.21 (s, 1H, H2 ), 13.1 (br s, 2H, H1 & H6 ); δc (125 MHz, d6-DMSO): 113.7, 120.1, 124.6, 126.5, 129.0, 134.3, 138.0, 167.0; HRMS-ESI m/z: found: 163.0503; C8H7N2O2 requires: 163.0502 [M + H+ ]; ˉνmax/cm1 (KBr): 3316 s br, 1700 s, 1619 m, 1592 m, 1509 m, 1285 s, 1201 m, 1145 m, 1078 m, 1056 w, 943 m, 858 s, 745 s, 638 m, 601 m.

1H-indazole-7-carboxylic acid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1H-indazole-7-carboxylic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 268)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Taizhou Blazer Biomedical Technology Co., Ltd.
0523-86112008 13915404123
sales@blazerbio.com China 88 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365
mina@chuanghaibio.com China 18126 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 997 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29812 58
Shanghai Arbor Chemical Co., Ltd.
021-60451682
act@arborchemical.com CHINA 904 58
TianYuan Pharmaceutical CO.,LTD
+86-755-23284190 13684996853
sales@tianpharm.com CHINA 304 58
Accela ChemBio Inc.
+1-858-6993322
info@accelachem.com United States 21193 58
Alchem Pharmtech,Inc.
8485655694
sales@alchempharmtech.com United States 63687 58

677304-69-7()Verwandte Suche:


  • 7-INDAZOLE CARBOXYLLIC ACID
  • 1H-INDAZOLE-7-CARBOXYLIC ACID
  • 7-INDAZOLE CARBOXYLIC ACID
  • 7-(1H)Indazole carboxylic acid
  • 1H-Indazol-7-carboxylic acid
  • 7-Carboxy-1H-indazole
  • Niraparib Intermediate4
  • 677304-69-7
  • CgH6N2O2
  • 1H-Indazole-7-carboxylic aid
  • 1H-Indazole-7-carboxylic acid
  • 677304-69-7
  • Amines
  • C8
  • Chemical Synthesis
  • New Products for Chemical Synthesis
  • Nitrogen Compounds
  • Organic Building Blocks
  • Indazoles
  • Building Blocks
  • Indazole
Copyright 2019 ? ChemicalBook. All rights reserved
来宾市| 九江市| 连平县| 灌南县| 淳安县| 济源市| 罗江县| 年辖:市辖区| 孝昌县| 昭平县| 弋阳县| 敦煌市| 阿坝县| 苏尼特左旗| 尚义县| 肥城市| 长兴县| 黑龙江省| 阳春市| 扶绥县| 澄城县| 开平市| 台北县| 岚皋县| 大名县| 宁城县| 运城市| 华池县| 城步| 土默特右旗| 桃江县| 遂昌县| 阳高县| 九龙城区| 左贡县| 巴林右旗| 五家渠市| 隆回县| 灌南县| 都匀市| 拜泉县|