MMP-2/MMP-9 INHIBITOR IV
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- CAS-Nr.
- 292605-14-2
- Englisch Name:
- MMP-2/MMP-9 INHIBITOR IV
- Synonyma:
- SB-3CT;CS-860;SB−SB-3CT (SB 3CT;SB-3CT, 10 mM in DMSO;MMP-2/MMP-9 INHIBITOR IV;MMP-2/MMP-9 INHIBITITOR IV;SB-3CT, MMP-2 and MMP-9 inhibitor;[[(4-Phenoxyphenyl)sulfonyl]methyl]thiirane;2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane
- CBNumber:
- CB9223336
- Summenformel:
- C15H14O3S2
- Molgewicht:
- 306.4
- MOL-Datei:
- 292605-14-2.mol
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MMP-2/MMP-9 INHIBITOR IV Eigenschaften
- Schmelzpunkt:
- 92-96°C
- Siedepunkt:
- 501.4±46.0 °C(Predicted)
- Dichte
- 1.329±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- DMSO: >20mg/mL
- Aggregatzustand
- powder
- Farbe
- white to off-white
- InChI
- 1S/C15H14O3S2/c16-20(17,11-14-10-19-14)15-8-6-13(7-9-15)18-12-4-2-1-3-5-12/h1-9,14H,10-11H2
- InChIKey
- LSONWRHLFZYHIN-UHFFFAOYSA-N
- SMILES
- O=S(=O)(CC1CS1)c2ccc(Oc3ccccc3)cc2
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xi |
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| R-S?tze: |
36 |
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| S-S?tze: |
26 |
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| WGK Germany |
3 |
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| HS Code |
29349990 |
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| Speicherklasse |
11 - Combustible Solids |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
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| Sicherheit |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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MMP-2/MMP-9 INHIBITOR IV Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
SB 3CT is a selective and potent gelatinase inhibitor which may be used for the treatment of brain metastasis.
Biochem/physiol Actions
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor. Matrix metalloproteinases (MMPs) are involved in a number of activities including angiogenesis and embryogenesis. In particular, gelatinases A (MMP-2) and B (MMP-9), are thought to facilitate tumor metastasis. SB-3CT exhibits a covalent mechanism based behavior in inhibition of MMP-2 and MMP-9. This inhibitor appears to have similarity to TIMP-1 and TIMP-2 in the slow-binding component of inhibition. SB-3CT has been shown to directly bind to the zinc in the catalytic site of MMP-2. SB-3CT does not affect the activities of MMP-1 (Ki = 206 μM) MMP-3 (Ki = 15 μM), or MMP-7 (Ki = 96 μM).
MMP-2/MMP-9 INHIBITOR IV Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
MMP-2/MMP-9 INHIBITOR IV Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 147)Lieferanten
- MMP-2/MMP-9 INHIBITITOR IV
- MMP-2/MMP-9 INHIBITOR IV
- 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane
- [[(4-Phenoxyphenyl)sulfonyl]methyl]thiirane
- SB-3CT (This product is only available in Japan.)
- CS-860
- MMP-2/MMP-9 Inhibitor IV - CAS 292605-14-2 - Calbiochem
- Thiirane, [[(4-phenoxyphenyl)sulfonyl]methyl]-
- Thiirane, 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-
- SB&minus
- SB-3CT, MMP-2 and MMP-9 inhibitor
- SB-3CT, 10 mM in DMSO
- 2-[(4-PHENOXYBENZENE SULFONYL)METHYL] THIIRANE, 98%min
- SB-3CT (SB 3CT
- SB-3CT
- 292605-14-2
- 2922605-14-2
- Inhibitors
