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Postion:Product Catalog >Cardamonin
Cardamonin
  • Cardamonin

Cardamonin NEW

Price $38 $60 $98
Package 2mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: Cardamonin CAS No.: 18956-16-6
Purity: 99.78% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

NameCardamonin
DescriptionCardamonin (Cardamomin) is a chalcone isolated from Alpiniae katsumadai. It has anticancer, anti-inflammatory, antimicrobial, antioxidant and anti-diabetic activities. It can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2, inhibit the growth of breast cancer, and can be used to study acute kidney injury and chronic renal fibrosis.
In vitroThe cell viabilities of H9C2 and HL-1 treated with different concentrations of Cardamonin (0, 1.5, 3.125, 6.25, 12.5, 25, 50 and 100 μM) for 24?h were not remarkably changed, suggesting that Cardamonin under the tested doses showed no significant cytotoxicity to cells. [1]
In vivoThe male C57BL/6?J mice (8 weeks old, 20–22?g). The Cardamonin treatment group (DOX?+? Cardamonin) was pretreated with Cardamonin (20, 40 or 80?mg/kg/day) by gavage, and mice were then intraperitoneal injected with DOX. Cardamonin does-dependently increased the body weight of mice challenged with DOX. We also found that the ratio of heart weight to body weight was markedly increased by DOX, which was, however, decreased by Cardamonin treatment in a dose-dependent manner. [1]
StorageKeep away from moisture,Keep away from direct sunlight,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (37 mM), Solution.
10% DMSO+90% Saline : < 10 mg/mL (37 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
DMSO : 250 mg/mL (924.97 mM), Sonication is recommended.
Keywordsβcatenin | Wnt/β-catenin | Wnt/betacatenin | Wnt/b-catenin | Wnt | TRPVChannel | TRPV Channel | TRPChannel | TRP Channel | STAT3 | NF-κB | NFκB | NF-kB | NFkB | mTOR | COX-2 | beta-catenin | betacatenin | bcatenin | Antioxidant | Akt
Inhibitors RelatedStavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Ethyl linoleate | D-Psicose | Formamide | Trometamol | Alginic acid | Sildenafil citrate
Related Compound LibrariesPolyphenolic Natural Product Library | Flavonoid Natural Product Library | Traditional Chinese Medicine Monomer Library | Pain-Related Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Natural Product Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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