[[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

S26948 is a peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC₅₀ = 8.83 nM in a transactivation assay). It is selective for PPARγ over PPARα, PPARβ/δ, and retinoid X receptor α (RXRα) at 10 μM. S26948 (30 mg/kg per day) decreases serum levels of glucose, triglycerides, non-esterified fatty acids, and insulin and increases hepatic palmitate oxidation in an ob/ob mouse model of type 2 diabetes. It decreases plasma levels of triglycerides and total and non-HDL cholesterol and the surface area of atherosclerotic lesions in the aortic sinus in an E2-KI transgenic mouse model of dyslipidemia and atherosclerosis fed a Western diet when administered at a dose of 30 mg/kg.

Verwenden

S26948 is a peroxisome proliferator-activated receptor γ modulator with potent antidiabetes and antiatherogenic effects.

[[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

[[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15838	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44918	58
TargetMol Chemicals Inc.	4008200310 15002144251	marketing@tsbiochem.com	China	24957	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11972	58
Cayman Chemical Company	--	sales@caymanchem.com	China	6838	58

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• [[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-1,3-propanedioicaciddimethylester
• 2-[[4-[2-(6-Benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-propanedioic acid 1,3-dimethyl ester
• S26948
• S 26948 >=98% (HPLC)
• S26948,S-26948
• Propanedioic acid, 2-[[4-[2-(6-benzoyl-2-oxo-3(2H)-benzothiazolyl)ethoxy]phenyl]methyl]-, 1,3-dimethyl ester
• 353280-43-0
• C28H25NO7S