1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid
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- CAS-Nr.
- 64096-87-3
- Englisch Name:
- 1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid
- Synonyma:
- 1,1-Dioxo-hexahydro-1l6-thiopyran-4-carboxylic acid;1,1-Dioxo-tetrahydrothiop...;Tetrahydrothiopyran-4-carboxylic;1.1-Dioxo-hexahydro-116-thiopyran;1,1-Dioxo-1lambda(6)-thiane-4-carboxylicacid;1,1-Dioxohexahydrothiopyran-4-carboxylic acid;1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid;1-Dioxo-hexahydro-1l6-thiopyran-4-carboxylic acid;Tetrahydrothiopyran-4-carboxylic acid 1,1-dioxide;tetrahydro-thiopyrane-4-carboxylic acid 1,1-dioxide
- CBNumber:
- CB92548536
- Summenformel:
- C6H10O4S
- Molgewicht:
- 178.21
- MOL-Datei:
- 64096-87-3.mol
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1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid Eigenschaften
- Schmelzpunkt:
- 195-196℃ (acetone ligroine )
- Siedepunkt:
- 456.6±38.0 °C(Predicted)
- Dichte
- 1.422±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.05±0.20(Predicted)
- Aggregatzustand
- powder
- Farbe
- White to off-white
- InChI
- InChI=1S/C6H10O4S/c7-6(8)5-1-3-11(9,10)4-2-5/h5H,1-4H2,(H,7,8)
- InChIKey
- RPJRJUVGGDVVDF-UHFFFAOYSA-N
- SMILES
- C1S(=O)(=O)CCC(C(O)=O)C1
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
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P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H332 |
Gesundheitssch?dlich bei Einatmen. |
Akute Toxizit?t inhalativ |
Kategorie 4 |
Warnung |
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P261, P271, P304+P340, P312 |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
3,3-Dimethyl- 2, 4-dioxa-9-thiaspiro[5.5]undecane-1,5-dione-9, 9-dioxide 1 (20.0 g, 76.3 mmol) and then 6 N hydrochloric acid (60 mL) and Antifoam 204 (200 mg, 1 wt % relative to 1) were charged to a 250-mL, three-neck round-bottom flask, equipped with a mechanical stirrer and a thermocouple. The reaction was then heated to reflux, and the distillate was collected until the internal temperature reached 100 eC; after that, the reaction was allowed to reflux for an additional 8 hours or until LC/MS showed a complete conversion of 1 to 2. The reaction was then cooled to room temperature and held for ~12 h when the product crystallized from the solution. The slurry was cooled to 0 °C for 1 h and then filtered. The cake was dried in a vacuum oven at 60 eC, with nitrogen bleed, overnight to give the product as a white, crystalline solid 1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid (8.84 g, 49.6 mmol, 65% yield.
1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 120)Lieferanten
64096-87-3()Verwandte Suche:
- tetrahydro-thiopyrane-4-carboxylic acid 1,1-dioxide
- 1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid
- 1,1-Dioxo-tetrahydrothiop...
- Tetrahydrothiopyran-4-carboxylic acid 1,1-dioxide
- 1,1-Dioxo-1lambda(6)-thiane-4-carboxylicacid
- 1,1-Dioxohexahydrothiopyran-4-carboxylic acid
- 1,1-dioxo-hexahydro-1λ6-thiopyran-4-carboxylic acid
- 2H-Thiopyran-4-carboxylic acid, tetrahydro-, 1,1-dioxide
- 1-Dioxo-hexahydro-1l6-thiopyran-4-carboxylic acid
- Tetrahydrothiopyran-4-carboxylic
- 1.1-Dioxo-hexahydro-116-thiopyran
- 1,1-Dioxo-hexahydro-1l6-thiopyran-4-carboxylic acid
- 64096-87-3
