Nampt Monoclonal Antibody (Clone OMNI 379) Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Nampt is a 52 kDa adipokine secreted by adipose tissue that is involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD
+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-
limiting NAD
+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates the insulin receptor and has insulin-
mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Nampt Monoclonal Antibody (Clone OMNI 379) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
