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1-(Dimethylamino)-2-phenylbutan-2-ol

1-(Dimethylamino)-2-phenylbutan-2-ol Struktur
5612-61-3
CAS-Nr.
5612-61-3
Englisch Name:
1-(Dimethylamino)-2-phenylbutan-2-ol
Synonyma:
Trimebutine Impurity 10;1-(Dimethylamino)-2-phenylbutan-2-ol;1-(DIMETHYLAMINO)-2-PHENYL-2-BUTANOL;α-[(Dimethylamino)methyl]-α-ethyl-benzenemethanol;Benzenemethanol, α-[(dimethylamino)methyl]-α-ethyl-;α-[(Dimethylamino)methyl]-α-ethyl-benzenemethanol, CAS 5612-61-3
CBNumber:
CB92681558
Summenformel:
C12H19NO
Molgewicht:
193.29
MOL-Datei:
5612-61-3.mol

1-(Dimethylamino)-2-phenylbutan-2-ol Eigenschaften

Siedepunkt:
78-79 °C(Press: 1 Torr)
Dichte
0.9645 g/cm3
L?slichkeit
DCM, Ethyl Amine
Aggregatzustand
Oil
pka
14.13±0.29(Predicted)
Farbe
Colorless

Sicherheit

1-(Dimethylamino)-2-phenylbutan-2-ol Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

α-[(Dimethylamino)methyl]-α-ethyl-benzenemethanol is an intermediate in the preparation of pharmaceutical goods.

Synthese

1-(Dimethylamino)-2-phenylbutan-2-ol is primarily synthesised via a Strecker synthesis-based route. Strecker Synthesis-Based Route: This multi-step synthesis begins with the reaction of propiophenone, dimethylamine, and a cyanide source (like sodium cyanide) to form the α aminonitrile, 2-(N,N-dimethylamino)-2-phenylbutyronitrile.  This intermediate then undergoes hydrolysis to the corresponding carboxylic acid, followed by esterification and finally reduction of the ester to yield the target amino alcohol.
Synthesis of 1-(DIMETHYLAMINO)-2-PHENYL-2-BUTANOL

1-(Dimethylamino)-2-phenylbutan-2-ol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


1-(Dimethylamino)-2-phenylbutan-2-ol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • 1-(DIMETHYLAMINO)-2-PHENYL-2-BUTANOL
  • 1-(Dimethylamino)-2-phenylbutan-2-ol
  • Benzenemethanol, α-[(dimethylamino)methyl]-α-ethyl-
  • α-[(Dimethylamino)methyl]-α-ethyl-benzenemethanol
  • Trimebutine Impurity 10
  • α-[(Dimethylamino)methyl]-α-ethyl-benzenemethanol, CAS 5612-61-3
  • 5612-61-3
  • Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
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