CFI-400945

1338806-73-7

CAS-Nr.: 1338806-73-7

Englisch Name:: CFI-400945

Synonyma:: ocifisertib;CFI-400945;CFI-400945 (CFI400945;CFI-400945 (free base);Ocifisertib（CFI-400945 free base）;CFI400945 free base,CFI 400945 free base;Ocifisertib（CFI-400945 free base）, 10 mM in DMSO;(1R,2S)-2-(3-((E)-4-(((2R,6S)-2,6-Dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one;(1R,2S)-2-(3-((E)-4-(((2R,6S)-2,6-Dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one;(1R,2S)-2-[3-[(E)-2-[4-[[(2S,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]vinyl]-1H-indazol-6-yl]-5'-methoxy-spiro[cyclopropane-1,3'-indoline]-2'-one

CBNumber:: CB92716177

Summenformel:: C33H34N4O3

Molgewicht:: 534.65

MOL-Datei:: 1338806-73-7.mol

Request For Quotation

Eigenschaften Sicherheit Verwendungswort Produktionsfirma 83

CFI-400945 Eigenschaften

Siedepunkt:: 751.5±60.0 °C(Predicted)

Dichte: 1.32±0.1 g/cm3(Predicted)

storage temp.: Store at -20°C

L?slichkeit: insoluble in H2O; ≥109.8 mg/mL in DMSO; ≥93 mg/mL in EtOH

Aggregatzustand: crystalline solid

pka: 13.09±0.40(Predicted)

Farbe: White to yellow

Sicherheit

CFI-400945 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(1R,2S)-2-[3-[(1E)-2-[4-[[(2R,6S)-2,6-Dimethyl-4-morpholinyl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5''-methoxy-spiro[cyclopropane-1,3''-[3H]indol]-2''(1''H)-one selectively inhibits polo-like kinase 4 (PLK4), which is a serine/threonine protein kinase that regulates centriole duplication during the cell cycle. PLK4 is a therapeutic target for various cancers.

CFI-400945 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CFI-400945 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 83)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471;	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	39037	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8615965530500	nickzhang@hangyubiotech.com	China	9947	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58
Suzhou ARTK Medchem Co., Ltd.	+8618118463618	sales1@artkmedchem.com	China	39021	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131956	58
Shanghai Boyle Chemical Co., Ltd.		sales@boylechem.com	China	2922	55

CFI-400945
CFI-400945 (free base)
CFI-400945 (CFI400945
Spiro[cyclopropane-1,3'-[3H]indol]-2'(1'H)-one, 2-[3-[(1E)-2-[4-[[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5'-methoxy-, (1R,2S)-
CFI400945 free base,CFI 400945 free base
(1R,2S)-2-[3-[(E)-2-[4-[[(2S,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]vinyl]-1H-indazol-6-yl]-5'-methoxy-spiro[cyclopropane-1,3'-indoline]-2'-one
Ocifisertib（CFI-400945 free base）
(1R,2S)-2-(3-((E)-4-(((2R,6S)-2,6-Dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one
Ocifisertib（CFI-400945 free base）, 10 mM in DMSO
(1R,2S)-2-(3-((E)-4-(((2R,6S)-2,6-Dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one
ocifisertib
1338806-73-7
338806-73-7
API

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