Anti-Strin Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
Anti-RNF138 antibody detects endogenous levels of total RNF138 protein.
Biochem/physiol Actions
Upregulation of RNF138 (RING (really interesting new gene) finger protein 138) induces polyubiquitination and increases the synthesis/degradation of CaV2.1 (voltage gated calcium channel). In response to DNA damage, RNF138 is localized to the DNA damage site mediated by zinc fingers. Deletion of RNF138 increases the sensitivity to DNA damaging agents and chromosomal instability. RNF138 is upregulated in gliomas.
Anti-Strin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte