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ANTI-DYSTROPHIN

ANTI-DYSTROPHIN Struktur
CAS-Nr.
Englisch Name:
ANTI-DYSTROPHIN
Synonyma:
ANTI-DYSTROPHIN;ANTI-DYSTROPHIN, MID-ROD;ANTI-DYSTROPHIN (C-TERMINUS);ANTI-DYSTROPHIN (ROD DOMAIN);ANTI-DYSTROPHIN (N-TERMINUS);Anti-DMD antibody produced in rabbit;Anti-Dystrophin antibody produced in rabbit;Monoclonal Anti-Dystrophin antibody produced in mouse
CBNumber:
CB9313761
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

ANTI-DYSTROPHIN Eigenschaften

storage temp. 
-20°C
Aggregatzustand
buffered aqueous glycerol solution
Biologische Quelle
rabbit

Sicherheit

Kennzeichnung gef?hrlicher Xn
R-S?tze: 21/22-22
S-S?tze: 36/37
WGK Germany  3
Speicherklasse 13 - Non Combustible Solids

ANTI-DYSTROPHIN Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Monoclonal Anti-Dystrophin antibody produced in mouse has been used in
  • immunohistochemistry
  • immunofluorescence
  • double immunofluorescence terminal dUTP nick-end labeling (TUNEL)
  • immunoblotting

Allgemeine Beschreibung

Monoclonal Anti-Dystrophin (mouse IgG2b isotype) is derived from the MANDYS8 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Dystrophin is a structural protein on the inner face of the membrane, consisting of a 25-repeat, rod-like, triple-helical domain separating an N-terminal actin binding domain from two C-terminal domains, one of which is rich in cysteine.

Biochem/physiol Actions

In striated muscle cells, DMD (dystrophin) acts as a component of the multimeric protein dystrophin-associated glycoprotein (DGC) complex. It helps DGC to adhere with the extracellular matrix for various signalling pathways. It helps to maintain structural assembly of plasma membrane, regulates ion homeostasis and transmembrane signaling cascade. It stabilzes muscle fiber cells. It is associated with various muscular dystrophies, such as Duchenne/Becker muscular dystrophy, congenital muscular dystrophy and different forms of limb-girdle muscular dystrophy.

ANTI-DYSTROPHIN Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ANTI-DYSTROPHIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 18)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51395 80
Merck KGaA --
ordercn@merckgroup.com China 6394 58
Nanjing Weiwo Biotechnology Co., Ltd. --
CHINA 6423 58
Guangzhou Kati Biotechnology Co., Ltd. --
CHINA 6598 58

  • Monoclonal Anti-Dystrophin antibody produced in mouse
  • Anti-Dystrophin antibody produced in rabbit
  • Anti-DMD antibody produced in rabbit
  • ANTI-DYSTROPHIN (N-TERMINUS)
  • ANTI-DYSTROPHIN (ROD DOMAIN)
  • ANTI-DYSTROPHIN, MID-ROD
  • ANTI-DYSTROPHIN
  • ANTI-DYSTROPHIN (C-TERMINUS)
  • Alphabetical Index
  • Antibodies to Actin-associated Proteins/MyosinAntibodies
  • Antibodies to Cytoskeleton
  • Cell Biology
  • Clone Index
  • DAntibodies
  • M
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