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Econazol

Econazole Struktur
27220-47-9
CAS-Nr.
27220-47-9
Bezeichnung:
Econazol
Englisch Name:
Econazole
Synonyma:
ECONAZOLE;NSC 187789;ECONAZOLUM;(±)-Econazol;Econazole CRS;Econazole USP/EP/BP;Econazole (Standard);Econazole, 10 mM in DMSO;Econazole Solution, 100ppm;Miconazole EP Impurity B HCl
CBNumber:
CB9447792
Summenformel:
C18H15Cl3N2O
Molgewicht:
381.68
MOL-Datei:
27220-47-9.mol

Econazol Eigenschaften

Schmelzpunkt:
86.8°C
Siedepunkt:
533.8±50.0 °C(Predicted)
Dichte
1.33±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
L?slichkeit
Practically insoluble in water, very soluble in ethanol (96 per cent) and in methylene chloride.
pka
6.68±0.12(Predicted)
Aggregatzustand
Solid
Farbe
White to off-white
Wasserl?slichkeit
0.37g/L(ambient temperature)
Major Application
pharmaceutical small molecule
InChI
1S/C18H15Cl3N2O/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2
InChIKey
LEZWWPYKPKIXLL-UHFFFAOYSA-N
SMILES
Clc1c(ccc(c1)Cl)C(OCc3ccc(cc3)Cl)C[n]2cncc2
CAS Datenbank
27220-47-9(CAS DataBase Reference)
EPA chemische Informationen
Econazole (27220-47-9)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 24/25-36/37/39
WGK Germany  WGK 3
Speicherklasse 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Bildanzeige (GHS) Exclamation Mark (GHS07)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
Sicherheit

Econazol Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.

Chemische Eigenschaften

White or almost white powder

Verwenden

antineoplastic, anti-estrogen.
Econazole (Spectazole) is a synthetic imidazole. Econazole blocks C-14 demethylation of sterols, interfering with the biosynthesis of ergosterol, which results in disorganization of the fungal plasma cell membrane and increased permeability. It is active against dermatophytes, yeast, P. orbiculare, Aspergillus, Cladosporium, and Sporothrix.

Indications

Econazole (Spectazole) is a synthetic imidazole. Econazole blocks C-14 demethylation of sterols, interfering with the biosynthesis of ergosterol, which results in disorganization of the fungal plasma cell membrane and increased permeability. It is active against dermatophytes, yeast, P. orbiculare, Aspergillus, Cladosporium, and Sporothrix.

Antimicrobial activity

Broad-spectrum imidazole antimycotic with activity against almost all species of pathogenic fungi.

Solubility in organics

Econazole is soluble in methanol, acetic acid, and PEG 400; less soluble in ethanol, acetone, chloroform, and butanol; and barely soluble in water, ether, cyclohexane, and hexane.

Econazol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Econazol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 213)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hefei Lbao Physical & Chemical Science Co.,Ltd
+15184799099
lbaochemicals@gmail.com China 670 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29792 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763
sales@tnjchem.com China 34563 58
Win-Win chemical CO., Limited
+86-0086-577-64498589 +86-15355981851
sales@win-winchemical.com China 14304 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626
eric@witopchemical.com China 23541 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 20584 58
AFINE CHEMICALS LIMITED
+86-0571-85134551
sales@afinechem.com China 15073 58
Finetech Industry Limited
+86-27-8746-5837 +8619945049750
info@finetechnology-ind.com China 9539 58

27220-47-9(Econazol)Verwandte Suche:


  • 1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazol
  • 1-(2,4-dichloro-beta-((p-chlorobenzyl)oxy)phenethyl)-imidazol
  • 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1h-imidazole
  • ECONAZOLE
  • ECONAZOLUM
  • 1-[2,4-Dichloro-β-[(p-chlorobenzyl)oxy]phenethyl]imidazole
  • 1H-Imidazole, 1-[2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-
  • Imidazole, 1-[2,4-dichloro-β-[(p-chlorobenzyl)oxy]phenethyl]- (8CI)
  • NSC 187789
  • Econazole (base and/or unspecified salts)
  • 1-(1H-Imidazole-1-yl)-2-(2,4-dichlorophenyl)-2-(4-chlorobenzyloxy)ethane
  • 1-[2,4-Dichloro-β-(p-chlorobenzyloxy)phenethyl]-1H-imidazole
  • 1-[β-[(4-Chlorobenzyl)oxy]-2,4-dichlorophenethyl]-1H-imidazole
  • 1-(2-((4-Chlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
  • econazole:1-(2-((4-chlorophenyl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1h-IMIDAZOLE
  • 1-(2,4-Dichloro-B-((P-Chlorobenzyl)Oxy)Phenethyl)Imidazole
  • Econazole CRS
  • Econazole USP/EP/BP
  • Econazole Solution, 100ppm
  • Miconazole Nitrate EP Impurity B
  • (±)-Econazol
  • Econazole(Miconazole nitrate EP impurity B)
  • Econazole, 10 mM in DMSO
  • 1-[(2RS)-2-[[(4-chlorophenyl)methyl]oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
  • Econazole : 1-[(2RS)-2-[(4-Chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
  • Miconazole EP Impurity B HCl
  • Econazole (Standard)
  • 27220-47-9
  • C18H15Cl3N2O
  • Antibiotics
  • Antibiotics A-F
  • Antibiotics A to Z
  • BioChemical
  • FARESTON
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