BTS
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- CAS-Nr.
- 1576-37-0
- Englisch Name:
- BTS
- Synonyma:
- BTS;CLN3;Battenin;NSC 37123;N-Tosylbenzylamine;BTS, 10 mM in DMSO;N-Benzyl-p-tosylaMide;LABOTEST-BB LT00786416;N-Tosylphenylmethanamine;N-Tosylbenzenemethaneamine
- CBNumber:
- CB9457528
- Summenformel:
- C14H15NO2S
- Molgewicht:
- 261.34
- MOL-Datei:
- 1576-37-0.mol
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BTS Eigenschaften
- Schmelzpunkt:
- 115 °C
- Siedepunkt:
- 419.1±48.0 °C(Predicted)
- Dichte
- 1.204±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- L?slichkeit
- Chloroform (Slightly), Dichloromethane, Ethyl Acetate (Slightly)
- Aggregatzustand
- White crystalline solid
- pka
- 11.54±0.30(Predicted)
- Farbe
- White to Off-White
- Sensitive
- Light Sensitive
- InChI
- InChI=1S/C14H15NO2S/c1-12-7-9-14(10-8-12)18(16,17)15-11-13-5-3-2-4-6-13/h2-10,15H,11H2,1H3
- InChIKey
- WTHKAJZQYNKTCJ-UHFFFAOYSA-N
- SMILES
- C1(S(NCC2=CC=CC=C2)(=O)=O)=CC=C(C)C=C1
- CAS Datenbank
- 1576-37-0(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
WGK 3 |
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| RTECS-Nr. |
XT5490000 |
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| HS Code |
2935.90.9500 |
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| Speicherklasse |
11 - Combustible Solids |
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| Toxizit?t |
rat,LD,oral,> 500mg/kg (500mg/kg),National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 41, 1953. |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
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P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
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P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P304+P340 |
BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
| P405 |
Unter Verschluss aufbewahren. |
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BTS Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
BTS is an inhibitor of skeletal muscle myosin II ATPase activity that reduces the affinity of ADP-myosin for actin. It inhibits calcium-stimulated ATPase activity of rabbit muscle myosin subfragment 1 (S1) in an actin-independent manner with an IC
50 value of approximately 5 μM. It is selective for calcium-stimulated myosin II over human platelet myosin II, kinesin, pyruvate kinase, and lactate dehydrogenase at 100 μM. BTS (2 μM) inhibits the activity of skeletal muscle myosin, reversibly reducing the sliding velocity of heavy meromyosin in a gliding-filament assay. It inhibits isometric calcium-activated tension in isolated fast-twitch rabbit psoas muscle fibers (IC
50 = ~3 μM) but not in isolated slow-twitch rat trabeculae and papillary cardiac muscle. BTS is also an intermediate in the synthesis of sulfonamides.
Chemische Eigenschaften
White Solid
Verwenden
A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin interaction with F-actin. Does not affect platelet myosin II
Biologische Aktivit?t
Selective inhibitor of the ATPase activity of skeletal muscle myosin II subfragment 1 (S1) (IC 50 ~ 5 mM). Reversibly blocks gliding motility and suppresses force and twitch production in fast skeletal muscle.
BTS Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
BTS Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 175)Lieferanten
1576-37-0()Verwandte Suche:
- n-benzyl-p-toluenesulfonamid
- N-BENZYL-P-TOLUENESULFONAMIDE
- N-BENZYL-P-TOLUENESULPHONAMIDE
- LABOTEST-BB LT00786416
- BTS
- 4-METHYL-N-(PHENYLMETHYL)BENZENESULFONAMIDE
- N-BENZYL-4-METHYL-BENZENESULFONAMIDE
- N-Tosylbenzylamine
- N-Methyl-N-(phenylmethyl)benzenesulfonamide
- N-Tosylbenzenemethaneamine
- N-Tosylphenylmethanamine
- Benzyl(4-toluenesulfonyl)aMine
- N-Benzyl-p-tosylaMide
- NSC 37123
- ANTI-CLN3 (CENTER) antibody produced in rabbit
- Battenin
- CLN3
- 4-methyl-n-(phenylmethyl)-benzenesulfonamid
- N-Benzyl-p-ToluenesulfonaMide (BTS)
- BTS - CAS 1576-37-0 - Calbiochem
- Benzenesulfonamide,4-methyl-N-(phenylmethyl)-
- BTS
(N-Benzyl-p-toluenesulfonamide
- N-Benzyl-p-toluenesulfonamide >
- BTS, Ca2+-stimulated myosin S1 ATPase
- N-Benzyl-p-toluenesulfonic acid amine
- BTS, 10 mM in DMSO
- 1576-37-0
- A potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~5 μM) and reversibly blocks the gliding motility.
- Inhibitors
- ATPase
