DEOXYCHOLIC-2,2,4,4-D4 ACID
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- CAS-Nr.
- 112076-61-6
- Englisch Name:
- DEOXYCHOLIC-2,2,4,4-D4 ACID
- Synonyma:
- Deoxycholic acid-D;Deoxycholic-d4 Acid;D4-Deoxycholic Acid;2H4]-Deoxycholic acid;DEOXYCHOLIC-2,2,4,4-D4 ACID;Deoxycholic acid-2,2,4,4-d4;Deoxycholic Acid-D4 (Standard);Deoxycholic Acid-[d4] (Solution);Deoxycholic Acid-[d4] in Methanol;Deoxycholic acid (2,2,4,4-D?, 98%)
- CBNumber:
- CB9491841
- Summenformel:
- C24H40O4
- Molgewicht:
- 392.58
- MOL-Datei:
- 112076-61-6.mol
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DEOXYCHOLIC-2,2,4,4-D4 ACID Eigenschaften
- Schmelzpunkt:
- 171-174 °C
- Flammpunkt:
- 9℃
- storage temp.
- -20°C
- L?slichkeit
- DMSO (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- InChIKey
- KXGVEGMKQFWNSR-FCSCGBJGSA-N
- SMILES
- [H][C@@]12[C@]([C@](CC([2H])([2H])[C@@H](O)C3([2H])[2H])(C)[C@]3([H])CC2)([H])C[C@H](O)[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(O)=O
- CAS Number Unlabeled
- 83-44-3
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
Xn |
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| R-S?tze: |
22-36/37/38 |
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| S-S?tze: |
26-36 |
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| RIDADR |
UN1230 - class 3 - PG 2 - Methanol, solution |
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| WGK Germany |
3 |
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| Speicherklasse |
11 - Combustible Solids |
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| Hazard Classifications |
Acute Tox. 4 Oral |
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| Bildanzeige (GHS) |
 
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| Alarmwort |
Achtung
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| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H225 |
Flüssigkeit und Dampf leicht entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 2 |
Achtung |
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P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 |
| H370 |
Sch?digt die Organe. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 1 |
Achtung |
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P260, P264, P270, P307+P311, P321,P405, P501 |
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| Sicherheit |
| P210 |
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P403+P233 |
An einem gut belüfteten Ort aufbewahren. Beh?lter dicht verschlossen halten. |
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DEOXYCHOLIC-2,2,4,4-D4 ACID Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
Deoxycholic acid-d
4 (DCA-d
4) is intended for use as an internal standard for the quantification of DCA (Item Nos.
20756 |
18231) by GC- or LC-MS. DCA is a secondary bile acid that is formed
via microbial transformation of cholic acid in the colon. It can be conjugated to glycine or taurine to produce glycodeoxycholic acid (GDCA; ) or taurodeoxycholic acid (TDCA; ), respectively, in hepatocytes. DCA (0.2% v/v) inhibits spore germination induced by taurocholic acid (TCA; ) in seven
C. difficile strains, as well as inhibits growth and decreases the cytotoxicity of
C. difficile culture supernatants to Vero cells when used at a concentration of 0.02% v/v. It inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells when used at a concentration of 200 μM. Fecal and intestinal tissue levels of DCA are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet. Increased serum DCA levels have been found in patients with colorectal cancer.
Verwenden
Deoxycholic-2,2,4,4-d4 Acid (CAS# 112076-61-6) is a useful isotopically labeled research compound.
DEOXYCHOLIC-2,2,4,4-D4 ACID Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
DEOXYCHOLIC-2,2,4,4-D4 ACID Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 53)Lieferanten
112076-61-6()Verwandte Suche:
- DEOXYCHOLIC-2,2,4,4-D4 ACID
- Deoxycholic acid-2,2,4,4-d4
- Deoxycholic-d4 Acid
- Deoxycholic acid-D
- Deoxycholic Acid-[d4] (Solution)
- DEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 100 UG/ML IN METHANOL
- Deoxycholic Acid-d4 MaxSpec? Standard
- 2H4]-Deoxycholic acid
- Deoxycholic-2,2,4,4-d4 Acid/Deoxycholic acid-d4
- DEOXYCHOLICACID(2,2,4,4-D4) IN METHANOL
- Deoxycholic Acid-[d4] in Methanol
- Deoxycholic acid-2,2,4,4-d4
- D4-Deoxycholic Acid
- Deoxycholic acid (2,2,4,4-D?, 98%) 100 μg/mL in methanol
- Deoxycholic acid (2,2,4,4-D?, 98%)
- Deoxycholic Acid-D4 (Standard)
- 112076-61-6
- Steroids & Hormones - 13C & 2H
- Alphabetical Listings
- DStable Isotopes
- Labeled Bioactive Compounds
- Stable Isotopes
- Steroids