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Pilsicainide hydrochloride

Pilsicainide hydrochloride Struktur
88069-49-2
CAS-Nr.
88069-49-2
Englisch Name:
Pilsicainide hydrochloride
Synonyma:
Pilsinic;Rizumcote;Alisrythm;Tatsupilljin;PILSICAININIDE;Pilsicainide hydrochoride;Pilsicainide-Hydrochlordie;Pilzicainide hydrochloride;PILSICAINIDE HYDROCHLORIDE;Pilsicainide HCl, 10 mM in DMSO
CBNumber:
CB9699294
Summenformel:
C17H24N2O
Molgewicht:
272.39
MOL-Datei:
88069-49-2.mol

Pilsicainide hydrochloride Eigenschaften

Schmelzpunkt:
212-214°
storage temp. 
room temp
L?slichkeit
Chloroform (Slightly), Water (Slightly)
Aggregatzustand
powder
Farbe
white to beige
Wasserl?slichkeit
deionized water: >5mg/mL
InChI
1S/C17H24N2O.ClH/c1-13-6-3-7-14(2)16(13)18-15(20)12-17-8-4-10-19(17)11-5-9-17;/h3,6-7H,4-5,8-12H2,1-2H3,(H,18,20);1H
InChIKey
NZOSVDHCTCLGEB-UHFFFAOYSA-N
SMILES
Cl.Cc1cccc(C)c1NC(=O)CC23CCCN2CCC3
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
HS Code  2933.99.7000
Speicherklasse 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Toxizit?t LD50 in mice (mg/kg): 410 s.c. (Miyano, 1985)
Bildanzeige (GHS) Skull and Crossbones (GHS06)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Pilsicainide hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Pilsicainide hydrochloride is a new pynolizidine lidocaine derivative with antiarrhythmic activity. It is the first pharmaceutical product introduced by Suntory and was solely developed in Japan. The compound is reported to be highly effective in the treatment of premature ventricular contraction. It has no anticholinergic or CNS activity and is not as likely as other class 1C antiarrhythmics to have restricted indications.

Verwenden

Pilsicainide hydrochloride has been used as a sodium channel blocker:
  • to study its effects on electrophysiological parameters in guinea pig pulmonary vein preparation
  • to study its effects on Ca2+release and arrhythmic events in Andersen-Tawil syndrome induced pluripotent stem cells (ATS-iPSC)-derived cardiomyocytes
  • to study its electrophysiological effects on the guinea pig atrium

Pilsicainide hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Pilsicainide hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 117)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29640 60
Beijing Cooperate Pharmaceutical Co.,Ltd
010-60279497
sales01@cooperate-pharm.com CHINA 1803 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21586 55
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29812 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49979 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569262 +86-15003564040
1056@dideu.com China 3970 58
SIMAGCHEM CORP
+86-5922680277 +86-13806087780
sale@simagchem.com China 17346 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32467 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739
info@dycnchem.com China 52704 58
changzhou huayang technology co., ltd
+8615250961469
2571773637@qq.com China 9653 58

88069-49-2()Verwandte Suche:


  • Pilzicainide hydrochloride
  • Rizumcote
  • Tatsupilljin
  • Pilsicainide-Hydrochlordie
  • N-(2,6-Dimethylphenyl)-2-(hexahydro-1H-pyrrolizin-7a-yl)acetamide hydrochloride
  • n-(2,6-dimethylphenyl)-2-(1,2,3,5,6,7-hexahydropyrrolizin-8-yl)acetamide hydrochloride
  • PILSICAINIDE HYDROCHLORIDE
  • PILSICAINIDE HYDROCHLORIDE HEMIHYDRATE
  • PILSICAININIDE
  • Pilsicainide hydrochoride
  • PILSICAINIDEHYDROCHLORIDE(FORRESEARCHONLY)
  • Pilsicainide Hydrochloride and intermediates
  • Alisrythm
  • Pilsinic
  • Pilsicainide hydrochloride USP/EP/BP
  • C17H24N2O Pilsicainide hydrochloride 88069-49-2
  • atrial tachyarrhythmias,SUN-1165,Pilsicainide HCl,antiarrhythmic,inhibit,orally active,SUN1165,Inhibitor,Na+ channels,Na channels,Pilsicainide,Sodium Channel
  • Pilsicainide HCl, 10 mM in DMSO
  • 88069-49-2
  • C17H24N2O
  • C17H24N2OHCl
  • C17H24N2OHCl12H2O
  • APIs
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