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Avermectin A1a, 5-O-Demethyl-22,23-dihydro-

Avermectin A1a, 5-O-demethyl-22,23-dihydro- Struktur
71827-03-7
CAS-Nr.
71827-03-7
Bezeichnung:
Avermectin A1a, 5-O-Demethyl-22,23-dihydro-
Englisch Name:
Avermectin A1a, 5-O-demethyl-22,23-dihydro-
Synonyma:
Ivermectin B1a;IvermectinH2B1a;Ivermectin B1a (>85%);Ivermectin Impurity 3;Dihydroavermectin B1a;Ivermectin B1a, 10 mM in DMSO;22,23-dihydroavermectin B1a in Methanol;5-O-Demethyl-22,23-dihydroavermectin A1a;22,23-Dihydro-5-O-demethylavermectin A1a;Avermectin A1a, 5-O-demethyl-22,23-dihydro-
CBNumber:
CB9928288
Summenformel:
C48H74O14
Molgewicht:
875.09
MOL-Datei:
71827-03-7.mol

Avermectin A1a, 5-O-Demethyl-22,23-dihydro- Eigenschaften

Schmelzpunkt:
155-157°
Siedepunkt:
717.97°C (rough estimate)
Dichte
1.0683 (rough estimate)
Brechungsindex
1.6130 (estimate)
storage temp. 
Store at -20°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
solid
pka
12.42±0.70(Predicted)
Farbe
white
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Bildanzeige (GHS) Skull and Crossbones (GHS06)
Alarmwort Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H301 Giftig bei Verschlucken. Akute Toxizit?t oral Kategorie 3 Achtung P264, P270, P301+P310, P321, P330,P405, P501
Sicherheit
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P301+P310 BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen.
P321 Besondere Behandlung
P330 Mund ausspülen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Avermectin A1a, 5-O-Demethyl-22,23-dihydro- Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Ivermectin B1a is the main component (>80%) of the anthelmintic ivermectin, which also contains ivermectin B1b (<20%; ). It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening and very long-lasting hyperpolarization/depolarization of the neuron/muscle cell, thereby blocking further function (EC50 = 104 nM). Formulations containing ivermectin inhibit replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Vero/hSLAM cells.

Definition

ChEBI: A macrocyclic lactone that is avermectin B1a in which the double bond present in the spirocyclic ring system has been reduced to a single bond. It is the major component of ivermectin.

Avermectin A1a, 5-O-Demethyl-22,23-dihydro- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Avermectin A1a, 5-O-Demethyl-22,23-dihydro- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 80)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Moxin Chemicals
+86-17320513646 +8617320513646
anna@molcoo.com China 10000 58
Guangzhou PI PI BIOTECH INC
+86-86-020-81716320 +8613602409664
Sales@pipitech.com China 973 55
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354
marketing@targetmol.com United States 32466 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19853 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+86-18621343501; +undefined18621343501
product@acmec-e.com China 33324 58
Aladdin Scientific

tp@aladdinsci.com United States 52923 58
Suzhou ARTK Medchem Co., Ltd.
+8618118463618
sales1@artkmedchem.com China 39021 58
SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580
cooperation@kean-chem.com China 40066 58
Shanghai Scibiotron Pharmaceutical Co., Ltd
+86-16621589600
contact@scibiotron.com China 5997 58
QUALITY CONTROL SOLUTIONS LTD.
+86-0755-66853366 +8613670046396
export03@qcsrm.com China 24342 58

71827-03-7(Avermectin A1a, 5-O-Demethyl-22,23-dihydro-)Verwandte Suche:


  • 22,23-Dihydro-5-O-demethylavermectin A1a
  • 5-O-Demethyl-22,23-dihydroavermectin A1a
  • Dihydroavermectin B1a
  • IvermectinH2B1a
  • (2Ae,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17ar,20R,20ar,20bs)-20,20B-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-3',4',5',6,6',10,11,14,15,17,17A,20,20A,20B-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-o-(2,6-dideoxy-3-o-methyl-alpha-L-arabino-hexopyranosyl)-3-o-methyl-alpha-L-arabino-hexopyranoside
  • Avermectin A1a, 5-O-demethyl-22,23-dihydro-
  • Ivermectin Impurity 3
  • Ivermectin B1a (>85%)
  • Ivermectin B1a-D2Q: What is Ivermectin B1a-D2 Q: What is the CAS Number of Ivermectin B1a-D2
  • Avermectin,Ivermectin,B1a,COVID-19,Parasite,Inhibitor,SARS coronavirus,Ivermectin B1a,anti-parasite,inhibit,SARS-CoV
  • Ivermectin 2-epimer (Dihydro Avermectin B1a)
  • 22,23-dihydroavermectin B1a in Methanol
  • Ivermectin B1a, 10 mM in DMSO
  • Ivermectin B1a
  • 71827-03-7
  • Organics
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