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ChemicalBook >> CAS DataBase List >>Squalene Oil

Squalene Oil

CAS No.
111-02-4
Chemical Name:
Squalene Oil
Synonyms
Supraene;SQUALENE OIL;trans-squalene;Squalen;(E,E,E,E)-Squalene;All-trans-Squalene;AddaVax;squalcnc;Spinacen;SPINACENE
CBNumber:
CB00131404
Molecular Formula:
C30H50
Molecular Weight:
410.72
MDL Number:
MFCD00008912
MOL File:
111-02-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-29 20:57:39
Product description Number Pack Size Price
Squalene ≥98%, liquid S3626 10ml $65
Squalene European Pharmacopoeia (EP) Reference Standard Y0002131 500 mg $180
Squalene ≥98%, liquid S3626 1l $971
Squalene certified reference material, pharmaceutical secondary standard PHR3519 1 g $469
Squalene analyticalstandard 442785 1000mg $329
More product size

Squalene Oil Properties

Melting point −75 °C(lit.)
Boiling point 285 °C25 mm Hg(lit.)
Density 0.858 g/mL at 25 °C(lit.)
vapor pressure 0Pa at 25℃
refractive index n20/D 1.494(lit.)
Flash point >230 °F
storage temp. 2-8°C
solubility DMSO : 16.67 mg/mL (40.59 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form liquid
color light yellow
Odor oil, faint odor
biological source animal
Water Solubility <0.1 g/100 mL at 19 ºC
Merck 14,8768
BRN 1728919
Major Application environmental
food and beverages
Cosmetics Ingredients Functions SOLVENT
SKIN CONDITIONING - EMOLLIENT
HAIR CONDITIONING
InChI 1S/C30H50/c1-25(2)15-11-19-29(7)23-13-21-27(5)17-9-10-18-28(6)22-14-24-30(8)20-12-16-26(3)4/h15-18,23-24H,9-14,19-22H2,1-8H3/b27-17+,28-18+,29-23+,30-24+
InChIKey YYGNTYWPHWGJRM-AAJYLUCBSA-N
SMILES CC(C)=CCCC(C)=CCCC(C)=CCC\C=C(/C)CCC=C(C)CCC=C(C)C
LogP 14.12 at 24℃
CAS DataBase Reference 111-02-4(CAS DataBase Reference)
FDA UNII 7QWM220FJH
NIST Chemistry Reference 2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (all-E)-(111-02-4)
EPA Substance Registry System Squalene (111-02-4)
UNSPSC Code 41116107
NACRES NA.25

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H304
Precautionary statements  P301+P310+P331
PPE Eyeshields, Gloves
Safety Statements  24/25
WGK Germany  2
RTECS  XB6010000
8-10-23
TSCA  TSCA listed
HS Code  29012980
Storage Class 10 - Combustible liquids
Hazard Classifications Asp. Tox. 1
Hazardous Substances Data 111-02-4(Hazardous Substances Data)
Toxicity mouse,LD50,intravenous,1800mg/kg (1800mg/kg),Japanese Journal of Cancer Research. Vol. 76, Pg. 1021, 1985.
REACH Registrations Active
NFPA 704
1
3 0

Squalene Oil price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S3626 Squalene ≥98%, liquid 111-02-4 10ml $65 2026-04-30 Buy
Sigma-Aldrich Y0002131 Squalene European Pharmacopoeia (EP) Reference Standard 111-02-4 500 mg $180 2026-04-30 Buy
Sigma-Aldrich S3626 Squalene ≥98%, liquid 111-02-4 1l $971 2026-04-30 Buy
Sigma-Aldrich PHR3519 Squalene certified reference material, pharmaceutical secondary standard 111-02-4 1 g $469 2026-04-30 Buy
Sigma-Aldrich 442785 Squalene analyticalstandard 111-02-4 1000mg $329 2026-04-30 Buy
Product number Packaging Price Buy
S3626 10ml $65 Buy
Y0002131 500 mg $180 Buy
S3626 1l $971 Buy
PHR3519 1 g $469 Buy
442785 1000mg $329 Buy

Squalene Oil Chemical Properties,Uses,Production

Chemical Properties

clear colourless to faint yellow oil

Uses

cosmetic and pharmaceutical excipient

Uses

Squalene is a natural triterpene that plays an important role in the synthesis of cholesterol, steroid hormones, and vitamin D in the human body. Squalene is commonly used as a biochemical precursor i n the preparation of steroids. Squalene is also a natural moisturizer with low acute toxicity and is not significant human skin irritants or sensitizers.

Uses

Bactericide; intermediate in manufacture of pharmaceuticals, organic coloring materials, rubber chemicals, aromatics and surface active agents.

Production Methods

Squalene is extracted from shark liver or synthesized from hexaphenyl-1,4-butanediyldiphosphonium dibromide and 6,10-dimethyl-5,9-undecadien-2-one (geranylacetone, industrial intermediate in the vitamin E synthesis).

Definition

ChEBI: A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration.

General Description

Clear, slightly yellow liquid with a faint odor. Density 0.858 g / cm3.

Air & Water Reactions

May become discolored on exposure to air. Insoluble in water.

Reactivity Profile

(all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene is incompatible with strong oxidizing agents. .

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition (all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene emits toxic fumes of carbon monoxide and carbon dioxide.

Fire Hazard

(all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene is probably combustible.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Squalene is a biosynthetic precursor to all steroids. It acts as a cytoprotective agent to normal cells exposed to carcinogens and antitumor agents. Squalene helps in equalizing the blood cholesterol levels. It increases the production of HDL (high density lipoprotein) and the excretion of LDL (low density lipoprotein). This helps in reducing the risk of heart disease and protects the less stable body fats from oxidation. It is also used in treating hypercholesterolemia. Squalene is known to improve the efficiency of cholesterol lowering drugs. It also serves as an antioxidant by preventing the effects of free radical. It protects skin from drying and other environmental conditions such as oxidation, ultraviolet rays and pollutants. Squalene is known to promote wound healing.

target

COX | STAT | FOXP3 | Nrf2 | SOD | GPx

Global( 344)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd.
+86-17531190177 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd
+86-17732866630 mina@chuanghaibio.com China 18126 58
Shaanxi Haibo Biotechnology Co., Ltd
+86-18629295024 qinhe02@xaltbio.com China 997 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126 info@binbobiological.com China 480 58
Shaanxi Xianhe Biotech Co., Ltd
+86-17709210191; +86-17709210191 Jerry@xhobio.com China 906 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 niki@zlchemi.com China 7245 58
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
+86-15225627621 +86-13213167925 jiuyitime@fdachem.com China 16511 58
Hebei Qujie Technology Co., Ltd.
+86-18533153922 +86-18533153922 admin@hbqujie.cn China 272 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21585 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29812 58

View Lastest Price from Squalene Oil manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
 SQUALENE OIL pictures 2026-05-28 SQUALENE OIL
7683-64-9
$30.00 1KG 98% 5000kg Hebei Chuanghai Biotechnology Co,.LTD
 Squalene pictures 2019-12-31 Squalene
7683-64-9
$7.00 1KG 99% 100KG Career Henan Chemical Co
  •  SQUALENE OIL pictures
  • SQUALENE OIL
    7683-64-9
  • $30.00
  • 98%
  • Hebei Chuanghai Biotechnology Co,.LTD
  •  Squalene pictures
  • Squalene
    7683-64-9
  • $7.00
  • 99%
  • Career Henan Chemical Co
trans-Spinacene SPINACENE Squalene,2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene Squalene, 99+% 100ML squalcnc (6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene Nikko Squalane EX triacontahexaene (6E,10E,14E,18E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene 14,18,22-tetracosahexaene,2,6,10,15,19,23-hexamethyl-(all-e)-10 2,6,10,15,19,23-hexamethyltetracosa- SQUALENE, 1000MG, NEAT Squalene, 99+% (2E,6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-Tetracosahexaene 2,6,10,14,18,22-Tetracosahe SQUALENE WITH GC 2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (2E,6E,10E,14E,18E)- Squalene: (2,610,15.19,23-Hexamethyltetracosahexane) 2, 6, 10, 15, 19, 23-hexamethyl-2, 6, 10, 14, 18, 22-tetracosahexanee 2,6,10,15,19,23-HEXAMETHYL-2, 6, 10, 14, 18, 22-TETRACOSAHEXENE (all-e)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene 2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene 2,6,10,15,19,23-hexamethyl-tetracosa-2,6,10,14,18,22-hexane 2,6,10,15,19,23-Hexamethyltetracosahexa-2,6,10,14,18,22-ene 6,10,14,18,22-Tetracosahexaene,2,6,10,15,19,23-hexamethyl-,(all-E)-2 Spinacen Squalene> Squalene Squalene AddaVax Super Squalene 2,6,10,14,18,22-Tetracosahexaene, 2,6,10,15,19,23-hexamethyl-, (6E,10E,14E,18E)- (E)-squalene TIANFU-CHEM -(all-E)-2,6,10,15,19,23-Hexamethyl-2,6,10,14,18,22-tetracosahexaene SQUALENE OIL trans-squalene (E,E,E,E)-Squalene All-trans-Squalene (all-E)-2,6,10 Vegan Squalene Squalene CRS/A1A Squalene in isooctane C16973700 Squalene Squalene, 10 mM in DMSO Squalene - plant origin Animal-derived squalene Squalene (Standard) Squalen Supraene 111-02-4 7級(jí)111-02-4 C30H50 CH32CCHCH2CH2CCH32CHCH22 Enzyme Inhibitors Cancer Research BioChemical Chemopreventive Agents Terpenes (Others) Terpenes
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