2-ETHOXY-4,6-DICHLOROPYRIMIDINE
- CAS No.
- 40758-65-4
- Chemical Name:
- 2-ETHOXY-4,6-DICHLOROPYRIMIDINE
- Synonyms
- 4,6-DICHLORO-2-ETHOXYPYRIMIDINE;2-ETHOXY-4,6-DICHLOROPYRIMIDINE;Pyrimidine, 4,6-dichloro-2-ethoxy-
- CBNumber:
- CB0208170
- Molecular Formula:
- C6H6Cl2N2O
- Molecular Weight:
- 193.03
- MDL Number:
- MFCD02262171
- MOL File:
- 40758-65-4.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Ethoxy-4,6-dichloropyrimidine Asreported | 274816 | 50mg | $370 |
| 2-Ethoxy-4,6-dichloropyrimidine Asreported | 274816 | 100mg | $512 |
| 2-Ethoxy-4,6-dichloropyrimidine Asreported | 274816 | 250mg | $708 |
| 2-Ethoxy-4,6-dichloropyrimidine Asreported | 274816 | 500mg | $984 |
| 2-Ethoxy-4,6-dichloropyrimidine Asreported | 274816 | 1g | $1274 |
| More product size | |||
| Boiling point | 283.5±43.0 °C(Predicted) |
|---|---|
| Density | 1.375±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -4.46±0.30(Predicted) |
| CAS DataBase Reference | 40758-65-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H318 |
| Precautionary statements | P280-P305+P351+P338-P310-P264-P270-P301+P312-P330-P501 |
| REACH Registrations | Inactive |
2-ETHOXY-4,6-DICHLOROPYRIMIDINE price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 274816 | 2-Ethoxy-4,6-dichloropyrimidine Asreported | 40758-65-4 | 50mg | $370 | 2026-06-03 | Buy |
| Usbiological | 274816 | 2-Ethoxy-4,6-dichloropyrimidine Asreported | 40758-65-4 | 100mg | $512 | 2026-06-03 | Buy |
| Usbiological | 274816 | 2-Ethoxy-4,6-dichloropyrimidine Asreported | 40758-65-4 | 250mg | $708 | 2026-06-03 | Buy |
| Usbiological | 274816 | 2-Ethoxy-4,6-dichloropyrimidine Asreported | 40758-65-4 | 500mg | $984 | 2026-06-03 | Buy |
| Usbiological | 274816 | 2-Ethoxy-4,6-dichloropyrimidine Asreported | 40758-65-4 | 1g | $1274 | 2026-06-03 | Buy |
2-ETHOXY-4,6-DICHLOROPYRIMIDINE Chemical Properties,Uses,Production
Application
2-Ethoxy-4,6-dichloropyrimidine is an important heterocyclic pesticide and pharmaceutical intermediate. It can be used to synthesize highly effective herbicides containing triazole pyrimidine rings, such as dichlorvos and chlorpyrifos; it can also be used to synthesize certain antibiotics. Therefore, 2-ethoxy-4,6-dichloropyrimidine has broad application prospects in organic synthesis, pharmaceuticals, and pesticides.
Synthesis
141-52-6
4489-34-3
40758-65-4
To a 500 mL reaction flask equipped with a stirrer and thermometer was added 43.5 g of 2-methylsulfonyl-4,6-dichloropyrimidine (0.19 mol) and 90 g of ethanol and stirred at room temperature. The reaction mixture was then cooled to 0 °C and 130 g of sodium ethanol solution (0.38 mol) at a concentration of 20 wt% was slowly added dropwise. Upon completion of the reaction, the reaction was terminated by sampling and analysis to confirm that the feedstock content was less than 1%. After adjusting the reaction system to neutral pH, a small amount of acetic acid was added and ethanol was recovered under reduced pressure. Subsequently, dichloromethane was added, the solvent was evaporated and water was added to separate the organic layer. The organic layer was washed once with water and the first solvent was recovered. 35.2 g of 2-ethoxy-4,6-dichloropyrimidine was obtained in 95.2% yield and 96.5% purity (HPLC analysis) by distillation under reduced pressure until no liquid was exuded.
Toxics Screening Level
The ITSL is being set at the default value of 0.1 μg/m3 with annual averaging.
References
[1] Patent: CN106866547, 2017, A. Location in patent: Paragraph 0021; 0022
2-ETHOXY-4,6-DICHLOROPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Jiangsu Liyang Kunlun Biological Technology Co., Ltd. | +86-13813530041 | z13813530041@126.com | China | 337 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3958 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 2-ETHOXY-4,6-DICHLOROPYRIMIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-20 | 2-Ethoxy-4,6-dichloropyrimidine
40758-65-4
|
$1.00 | 1kg | GC 90.0% | 20tons | Hebei Yanxi Chemical Co., Ltd. | |
 |
2025-04-04 | 2-Ethoxy-4,6-dichloropyrimidine
40758-65-4
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2025-04-02 | 2-ethoxy-4,6-dichloropyrimidine
40758-65-4
|
1000kg | 0.99 | 20 tons | Jiangsu Liyang Kunlun Biological Technology Co., Ltd. |
-
- 2-Ethoxy-4,6-dichloropyrimidine
40758-65-4
- $1.00
- GC 90.0%
- Hebei Yanxi Chemical Co., Ltd.
-
- 2-Ethoxy-4,6-dichloropyrimidine
40758-65-4
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-ethoxy-4,6-dichloropyrimidine
40758-65-4
- $0.00
- 0.99
- Jiangsu Liyang Kunlun Biological Technology Co., Ltd.
