(6-BROMO-PYRIDIN-3-YL)-METHANOL
- CAS No.
- 122306-01-8
- Chemical Name:
- (6-BROMO-PYRIDIN-3-YL)-METHANOL
- Synonyms
- CAS:122306-01-8;2-Bromopyridine-5-methanol;6-Bromo-3-pyridinemethanol;6-BroMopyridine-3-Methanol;(6-BroMo-3-pyridyl)Methanol;3-Pyridinemethanol, 6-bromo-;6-Bromo-3-pyridinemethanol >2-BroMo-5-pyridineMethanol, 95%;(6-BROMO-PYRIDIN-3-YL)-METHANOL;(2-BROMO-PYRIDIN-5-YL)-METHANOL
- CBNumber:
- CB0243243
- Molecular Formula:
- C6H6BrNO
- Molecular Weight:
- 188.02
- MDL Number:
- MFCD04974508
- MOL File:
- 122306-01-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 6-Bromopyridine-3-methanol 97% | 762539 | 1g | $49.1 |
| 6-Bromo-3-pyridinemethanol >98.0%(GC)(T) | B3494 | 1g | $102 |
| 6-Bromo-3-pyridinemethanol >98.0%(GC)(T) | B3494 | 5g | $406 |
| (6-Bromopyridin-3-yl)methanol Asreported | 265716 | 1g | $340 |
| (6-Bromopyridin-3-yl)methanol Asreported | 265716 | 2g | $466 |
| More product size | |||
| Melting point | 48-51℃ |
|---|---|
| Boiling point | 314.3±27.0 °C(Predicted) |
| Density | 1.668±0.06 g/cm3(Predicted) |
| Flash point | >110℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 13.29±0.10(Predicted) |
| color | White to Light yellow to Light orange |
| InChI | 1S/C6H6BrNO/c7-6-2-1-5(4-9)3-8-6/h1-3,9H,4H2 |
| InChIKey | QPPDKOIDAYZUHN-UHFFFAOYSA-N |
| SMILES | OCc1ccc(Br)nc1 |
| CAS DataBase Reference | 122306-01-8 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-37/38-41 | |||||||||
| Safety Statements | 26-39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2933399990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
(6-BROMO-PYRIDIN-3-YL)-METHANOL price More Price(99)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 762539 | 6-Bromopyridine-3-methanol 97% | 122306-01-8 | 1g | $49.1 | 2023-06-20 | Buy |
| TCI Chemical | B3494 | 6-Bromo-3-pyridinemethanol >98.0%(GC)(T) | 122306-01-8 | 1g | $102 | 2026-04-30 | Buy |
| TCI Chemical | B3494 | 6-Bromo-3-pyridinemethanol >98.0%(GC)(T) | 122306-01-8 | 5g | $406 | 2026-04-30 | Buy |
| Usbiological | 265716 | (6-Bromopyridin-3-yl)methanol Asreported | 122306-01-8 | 1g | $340 | 2026-06-03 | Buy |
| Usbiological | 265716 | (6-Bromopyridin-3-yl)methanol Asreported | 122306-01-8 | 2g | $466 | 2026-06-03 | Buy |
(6-BROMO-PYRIDIN-3-YL)-METHANOL Chemical Properties,Uses,Production
Uses
2-Bromo-5-pyridinemethanol is used as a pharmaceutical intermediate.
Synthesis
149806-06-4
122306-01-8
General procedure for the synthesis of 2-bromo-5-(hydroxymethyl)pyridine from 2-bromo-5-formylpyridine: Sodium borohydride (4.88 g, 0.026 mol) was added batchwise to a solution of 6-bromonicotinaldehyde (20.0 g, 0.11 mol) in methanol (108 mL) at 20-30 °C. The reaction mixture was stirred at room temperature for 2 hours. Subsequently, the reaction mixture was diluted with saturated aqueous ammonium chloride solution. The mixture was concentrated to remove methanol and the resulting aqueous solution was extracted with ethyl acetate. The organic phase was washed sequentially with saturated aqueous sodium bicarbonate and brine, dried over magnesium sulfate, filtered and concentrated to afford 2-bromo-5-(hydroxymethyl)pyridine (18.61 g, 92% yield) as a light yellow solid.1H-NMR (300 MHz, CDCl3) δ (ppm): 8.36 (d, J = 2.7Hz, 1H), 7.60 (dd, J = 8.1, 2.7Hz, 1H). 2.7 Hz, 1H), 7.49 (d, J = 8.1 Hz, 1H), 4.72 (s, 2H), 1.95 (s, 1H).
References
[1] Patent: WO2013/44360, 2013, A1. Location in patent: Paragraph 000299-000300
[2] Patent: WO2006/114213, 2006, A1. Location in patent: Page/Page column 29-30
[3] Patent: WO2012/177603, 2012, A2. Location in patent: Page/Page column 105-108
[4] Journal of Organic Chemistry, 2004, vol. 69, # 2, p. 250 - 262
[5] Dalton Transactions, 2012, vol. 41, # 3, p. 1074 - 1081
(6-BROMO-PYRIDIN-3-YL)-METHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 933 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from (6-BROMO-PYRIDIN-3-YL)-METHANOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-18 | (6-BROMO-PYRIDIN-3-YL)-METHANOL
122306-01-8
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2025-09-25 | (6-BROMO-PYRIDIN-3-YL)-METHANOL
122306-01-8
|
$3.00 | 1KG | 98% | Henan Fengda Chemical Co., Ltd | ||
 |
2022-09-12 | 2-BroMo-5-pyridineMethanol
122306-01-8
|
1G | 98%min | 50kg/month | Shanghai Rlavie Technology Co ltd |
-
- (6-BROMO-PYRIDIN-3-YL)-METHANOL
122306-01-8
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- (6-BROMO-PYRIDIN-3-YL)-METHANOL
122306-01-8
- $3.00
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 2-BroMo-5-pyridineMethanol
122306-01-8
- 98%min
- Shanghai Rlavie Technology Co ltd
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