2-BROMO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE
![2-BROMO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Structure](CAS2/GIF/1035219-96-5.gif)
- CAS No.
- 1035219-96-5
- Chemical Name:
- 2-BROMO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE
- Synonyms
- 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H);2-brome-6,7-dihydrothiazole[5,4-C]pyridin-4(5H)-one;2-BROMO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE;Thiazolo[5,4-c]pyridin-4(5H)-one, 2-bromo-6,7-dihydro-;2-bromo-6,7-dihydro-5H-[1,3]thiazolo[5,4-c]pyridin-4-one;2-bromo-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-4-one;2-Bromo-5,6,7,7a-tetrahydro-3aH-thiazolo[5,4-c]pyridin-4-one
- CBNumber:
- CB02469072
- Molecular Formula:
- C6H5BrN2OS
- Molecular Weight:
- 233.09
- MDL Number:
- MFCD14706758
- MOL File:
- 1035219-96-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | KRB21996 | 0.5g | $584.1 |
| 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | KRB21996 | 1g | $973.5 |
| 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | KRB21996 | 2g | $1298 |
| 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | KRB21996 | 5g | $2596 |
| 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | KRB21996 | 10g | $4543 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
2-BROMO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | KRB21996 | 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | 1035219-96-5 | 0.5g | $584.1 | 2026-06-04 | Buy |
| Biosynth | KRB21996 | 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | 1035219-96-5 | 1g | $973.5 | 2026-06-04 | Buy |
| Biosynth | KRB21996 | 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | 1035219-96-5 | 2g | $1298 | 2026-06-04 | Buy |
| Biosynth | KRB21996 | 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | 1035219-96-5 | 5g | $2596 | 2026-06-04 | Buy |
| Biosynth | KRB21996 | 2-Bromo-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-one | 1035219-96-5 | 10g | $4543 | 2026-06-04 | Buy |
2-BROMO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Chemical Properties,Uses,Production
Uses
2-Bromo-6,7-dihydrothiazo[5,4-C]pyridine-4(5H)-one is a pyridine organic compound that can be used as an organic intermediate.
Synthesis
![2-AMINO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE](/CAS2/GIF/26493-11-8.gif)
26493-11-8
![2-BROMO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE](/CAS2/GIF/1035219-96-5.gif)
1035219-96-5
The general procedure for the synthesis of 2-bromo-6,7-dihydrothiazolo[5,4-b]pyridin-4(5H)-ones using 2-amino-6,7-dihydrothiazolo[5,4-c]pyridin-4(5H)-ones as starting material was as follows: intermediate 3 (8 g, 39.8 mmol), copper(II) bromide (10.43 g, 46.68 mmol) and 3-methyl-1- Nitrosoxybutane (6.8 g, 58.35 mmol) were dissolved in acetonitrile (100 mL) and the reaction was stirred at room temperature for 1.5 hours. Upon completion of the reaction, the solvent was removed by vacuum evaporation. The resulting residue was dissolved in ethyl acetate and washed with water. The organic layer was separated, dried with anhydrous sodium sulfate, filtered and the solvent was evaporated in vacuum to give Intermediate 4 (5 g, 55% yield), which could be used in subsequent steps without further purification.
References
[1] Patent: WO2011/73339, 2011, A1. Location in patent: Page/Page column 43
[2] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 14, p. 4037 - 4043
[3] Patent: WO2015/101928, 2015, A1. Location in patent: Page/Page column 66; 67
2-BROMO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Preparation Products And Raw materials
2-BROMO-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDIN-4(5H)-ONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24597 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
| Shanghai Guangyang Jiali Biotechnology Co., Ltd | 13407521611 | 46993711@qq.com | China | 176 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Henan Rane Chemical Co., Ltd. | +86-18738066252 | info@ranechem.com | China | 2999 | 58 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14100 | 59 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9520 | 58 |
| Shanghai Keepontech Co.,Ltd | 021-54849683 13601642561 | sales@keepontech.com | China | 988 | 59 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
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