7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE
![7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE Structure](CAS/GIF/94220-38-9.gif)
- CAS No.
- 94220-38-9
- Chemical Name:
- 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE
- Synonyms
- 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE;1H-Pyrazolo[4,3-b]pyridine, 7-chloro-5-Methyl-
- CBNumber:
- CB0252779
- Molecular Formula:
- C7H6ClN3
- Molecular Weight:
- 167.6
- MDL Number:
- MFCD08236755
- MOL File:
- 94220-38-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 95% | OR305333 | 100mg | $81 |
| 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 95% | OR305333 | 250mg | $126 |
| 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 95% | OR305333 | 1g | $336 |
| 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine | 292679 | 100.00mg | $84 |
| 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine | 292679 | 250.00mg | $128 |
| More product size | |||
| Boiling point | 307.3±37.0 °C(Predicted) |
|---|---|
| Density | 1.438±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | 9.09±0.40(Predicted) |
| Appearance | Light brown to brown Solid |
| InChI | InChI=1S/C7H6ClN3/c1-4-2-5(8)7-6(10-4)3-9-11-7/h2-3H,1H3,(H,9,11) |
| InChIKey | GTYZRPHAMFVUEE-UHFFFAOYSA-N |
| SMILES | C12C=NNC1=C(Cl)C=C(C)N=2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| HS Code | 2933399990 |
7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR305333 | 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 95% | 94220-38-9 | 100mg | $81 | 2026-06-04 | Buy |
| Apolloscientific | OR305333 | 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 95% | 94220-38-9 | 250mg | $126 | 2026-06-04 | Buy |
| Apolloscientific | OR305333 | 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine 95% | 94220-38-9 | 1g | $336 | 2026-06-04 | Buy |
| Matrix Scientific | 292679 | 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine | 94220-38-9 | 100.00mg | $84 | 2026-05-19 | Buy |
| Matrix Scientific | 292679 | 7-Chloro-5-methyl-1H-pyrazolo[4,3-b]-pyridine | 94220-38-9 | 250.00mg | $128 | 2026-05-19 | Buy |
7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE Chemical Properties,Uses,Production
Synthesis
![5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDIN-7-OL](/CAS/GIF/268547-52-0.gif)
268547-52-0
![7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE](/CAS/GIF/94220-38-9.gif)
94220-38-9
Step 1: 5-methyl-1H-pyrazolo[4,3-b]pyridin-7-ol (4.58 g, 30.7 mmol) was dissolved in phosphorochloridic acid (30 mL) and the reaction was heated at 110 °C for 30 min. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently slowly poured into ice water. The pH of the mixture was adjusted with 6N NaOH solution to 5. The precipitated solid product was collected by filtration. The mother liquor layer was extracted with ethyl acetate (3 x 250 mL). The above solids were dissolved in the combined organic phases, washed with brine solution (1 x 250 mL), dried over anhydrous sodium sulfate, filtered and concentrated. Purification of the concentrate by short silica gel column chromatography afforded 7-chloro-5-methyl-1H-pyrazolo[4,3-b]pyridine (Compound Ie) as a light yellow solid (4.50 g, 26.8 mmol, 87% yield).GC/MS analysis: m/z = 167 (100%); LC/MS analysis: [M + H]+ = 168.
References
[1] Journal of Medicinal Chemistry, 2005, vol. 48, # 18, p. 5780 - 5793
[2] Patent: WO2006/44821, 2006, A1. Location in patent: Page/Page column 23-24
7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9333 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 |
View Lastest Price from 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE pictures](/ProductImageEN/2022-10/Small/c039b0a8-cda7-4b24-9af7-8e22e10b22c1.png) |
2025-04-04 | 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE
94220-38-9
|
1KG | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 7-CHLORO-5-METHYL-1H-PYRAZOLO[4,3-B]PYRIDINE
94220-38-9
- 98%
- Henan Aochuang Chemical Co.,Ltd.
