CMX 001
- CAS No.
- 444805-28-1
- Chemical Name:
- CMX 001
- Synonyms
- Brincidofovir;Brincidofovir (CMX001);CS-2275;CMX 001;HDP-CDV;HDP-HPMPC;HDP-cidofovir;CMX 001 - Bio-X ?;CMX001(Brincidofovir);Fampridine Impurity 23
- CBNumber:
- CB02627690
- Molecular Formula:
- C27H52N3O7P
- Molecular Weight:
- 561.69
- MDL Number:
- MFCD09970716
- MOL File:
- 444805-28-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Brincidofovir ≥98% (HPLC) | SML3155 | 5MG | $87.1 |
| Brincidofovir ≥98% (HPLC) | SML3155 | 25MG | $351 |
| Brincidofovir ≥98% | 35062 | 5mg | $83 |
| Brincidofovir ≥98% | 35062 | 10mg | $158 |
| Brincidofovir ≥98% | 35062 | 25mg | $330 |
| More product size | |||
| Melting point | > 177° C (dec.) |
|---|---|
| Boiling point | 688.6±65.0 °C(Predicted) |
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methanol (Sli |
| form | Solid |
| pka | 2.40±0.10(Predicted) |
| color | White to Off-White |
| Stability | Hygroscopic |
| InChIKey | WXJFKKQWPMNTIM-VWLOTQADSA-N |
| SMILES | P(CO[C@H](CO)CN1C(=O)N=C(N)C=C1)(=O)(O)OCCCOCCCCCCCCCCCCCCCC |
| FDA UNII | 6794O900AX |
| NCI Drug Dictionary | brincidofovir |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H317-H351-H361d |
| Precautionary statements | P202-P261-P264-P280-P301+P310-P302+P352 |
| WGK Germany | WGK 3 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Carc. 2 Repr. 2 Skin Sens. 1 |
CMX 001 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML3155 | Brincidofovir ≥98% (HPLC) | 444805-28-1 | 5MG | $87.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | SML3155 | Brincidofovir ≥98% (HPLC) | 444805-28-1 | 25MG | $351 | 2026-04-30 | Buy |
| Cayman Chemical | 35062 | Brincidofovir ≥98% | 444805-28-1 | 5mg | $83 | 2026-04-30 | Buy |
| Cayman Chemical | 35062 | Brincidofovir ≥98% | 444805-28-1 | 10mg | $158 | 2026-04-30 | Buy |
| Cayman Chemical | 35062 | Brincidofovir ≥98% | 444805-28-1 | 25mg | $330 | 2026-04-30 | Buy |
CMX 001 Chemical Properties,Uses,Production
Uses
Brincidofovir is an antiviral inhibitor, working against BK polymavirus replication in primary human urothelial cells. Cytostatic, cytotoxic agent.
Biological Activity
cmx001 is a broad spectrum antiviral agent [1].cmx001 has been reported to be active in vitro against a broad range of viruses from all five families of dsdna viruses infecting human with ec50 values of 0.02μm, 0.0004μm, 17μm , 0.045μm and 0.07μm for adenovirus, herpesvirus, papillomavirus, polyomavirus and orthopoxvirus, respectively. in addition, cmx001 has been revealed to arrest disease progression by inhibiting viral dna replication and thereby reducing viral burden. apart from these, initial studies has been demonstrated the efficacy of cmx001 for pre-exposure and post-exposure prophylaxis in mouse, rabbit, cynomolgus monkeys and human [1].
in vivo
Brincidofovir (BCV) (20 mg/kg; p.o.; on days 1, 3, 5, 7, 10, 14, 17, 21, and 24) extends survival in immune-deficient BALB/c nu/nu mice following lethal challenge with IHD-J-Luc VACV[3].
| Animal Model: | BALB/c nu/nu mice (infected with IHD-J-Luc VACV)[3] |
| Dosage: | 20 mg/kg |
| Administration: | P.o.; on days 1, 3, 5, 7, 10, 14, 17, 21, and 24 |
| Result: | On days 1, 3, and 5 maintained their weights initially but started to lose weight beginning on day 9 and succumbed between days 24 and 29 postchallenge. |
References
[1]lanier r1, trost l, tippin t, lampert b, robertson a, foster s, rose m, painter w, o'mahony r, almond m, painter g.development of cmx001 for the treatment of poxvirus infections. viruses. 2010 dec; 2(12):2740-2762.
CMX 001 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 | sales@sdperfect.com | China | 294 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 | info@afinechem.com | China | 15080 | 58 |
| NewCan Biotech Limited | +86-571-86912261 19975279805 | sales@newcanbio.com | China | 9985 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11680 | 58 |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | 1713330907@QQ.com | China | 2639 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
View Lastest Price from CMX 001 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-25 | Brincidofovir
444805-28-1
|
$48.00-173.00 | 98.00% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-27 | Brincidofovir
444805-28-1
|
1g | 98% HPLC | 1kg | shandong perfect biotechnology co.ltd | ||
 |
2024-11-12 | Brincidofovir
444805-28-1
|
$2500.00 | 1g | 98 | 500 Kg | R&D Scientific Inc. |
-
- Brincidofovir
444805-28-1
- $48.00-173.00
- 98.00%
- TargetMol Chemicals Inc.
-
- Brincidofovir
444805-28-1
- $0.00
- 98% HPLC
- shandong perfect biotechnology co.ltd
-
- Brincidofovir
444805-28-1
- $2500.00
- 98
- R&D Scientific Inc.
