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ChemicalBook >> CAS DataBase List >> Triptolide

Triptolide

Triptolide price.
  • $25 - $4741
  • Product name: Triptolide
  • CAS: 38748-32-2
  • MF: C20H24O6
  • MW: 360.4
  • EINECS:683-214-2
  • MDL Number:MFCD00210565
  • Synonyms:TRIPTOLIDE;TRIPTOLIDE, TRIPTERYGIUM WILFORDII;,7as,7bs,8as,8bs)- ;triptolid ;Triptolide, >=98%;TriptolidefromTripterygium wilfordii≥ 98% (HPLC);Triptolide(TPL);TRIPTOLIDE TLC
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Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
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  • Chem-Impex
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  • Usbiological
Package
  • 20mg
  • 10mM(1mLinDMSO)
  • 10mM*1mLinDMSO
  • 50mg
  • 1
  • 250mg
  • 25 mg
  • 10
  • 10mM(in1mLDMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • 1G
  • 10mM(in 1mL DMSO)
  • Manufactureraablocks
  • Product numberAA0035S7
  • Product descriptionTriptolide ≥98%
  • Packaging1mg
  • Price$36
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0035S7
  • Product descriptionTriptolide
  • Packaging2mg
  • Price$60
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0035S7
  • Product descriptionTriptolide 95%
  • Packaging5mg
  • Price$67
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0035S7
  • Product descriptionTriptolide
  • Packaging10mg
  • Price$126
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA0035S7
  • Product descriptionTriptolide 95%
  • Packaging25mg
  • Price$178
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA0035S7
  • Product descriptionTriptolide 97%
  • Packaging100mg
  • Price$246
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10401
  • Product descriptionTriptolide 98%
  • Packaging100MG
  • Price$265
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10401
  • Product descriptionTriptolide 98%
  • Packaging25MG
  • Price$100
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10401
  • Product descriptionTriptolide 98%
  • Packaging5MG
  • Price$35
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product number10401
  • Product descriptionTriptolide 98%
  • Packaging1G
  • Price$1760
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-T0237-M005
  • Product descriptionTriptolide ≥98%(HPLC)
  • Packaging5mg
  • Price$369
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0448-M001
  • Product descriptionTriptolide ≥98%(HPLC)
  • Packaging1mg
  • Price$25
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0448-M005
  • Product descriptionTriptolide ≥98%(HPLC)
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0448-M005
  • Product descriptionTriptolide ≥98%(HPLC)
  • Packaging5mg
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-T0237-M001
  • Product descriptionTriptolide ≥98%(HPLC)
  • Packaging1mg
  • Price$99
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0448-M010
  • Product descriptionTriptolide ≥98%(HPLC)
  • Packaging10mg
  • Price$140
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0035S7 Triptolide ≥98% 1mg $36 2026-05-28 Buy
aablocks AA0035S7 Triptolide 2mg $60 2026-05-28 Buy
aablocks AA0035S7 Triptolide 95% 5mg $67 2026-05-28 Buy
aablocks AA0035S7 Triptolide 10mg $126 2026-05-28 Buy
aablocks AA0035S7 Triptolide 95% 25mg $178 2026-05-28 Buy
aablocks AA0035S7 Triptolide 97% 100mg $246 2026-05-28 Buy
ACHEMBLOCK 10401 Triptolide 98% 100MG $265 2026-05-27 Buy
ACHEMBLOCK 10401 Triptolide 98% 25MG $100 2026-05-27 Buy
ACHEMBLOCK 10401 Triptolide 98% 5MG $35 2026-05-27 Buy
ACHEMBLOCK 10401 Triptolide 98% 1G $1760 2026-05-27 Buy
Adipogen Life Sciences CDX-T0237-M005 Triptolide ≥98%(HPLC) 5mg $369 2026-05-06 Buy
Adipogen Life Sciences AG-CN2-0448-M001 Triptolide ≥98%(HPLC) 1mg $25 2026-05-06 Buy
Adipogen Life Sciences AG-CN2-0448-M005 Triptolide ≥98%(HPLC) 5mg $90 2021-12-16 Buy
Adipogen Life Sciences AG-CN2-0448-M005 Triptolide ≥98%(HPLC) 5mg $90 2026-05-06 Buy
Adipogen Life Sciences CDX-T0237-M001 Triptolide ≥98%(HPLC) 1mg $99 2026-05-06 Buy
Adipogen Life Sciences AG-CN2-0448-M010 Triptolide ≥98%(HPLC) 10mg $140 2026-05-06 Buy

Properties

Melting point :226-227°C
alpha :D25 -154°
Boiling point :412.43°C (rough estimate)
Density :1.1656 (rough estimate)
refractive index :1.4450 (estimate)
storage temp. :2-8°C
solubility :DMSO: soluble
form :solid
pka :14.25±0.60(Predicted)
color :white to off-white
biological source :Tripterygium wilfordii
Merck :14,9747
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :DFBIRQPKNDILPW-CIVMWXNOSA-N
SMILES :O1[C@@]32[C@]5(O[C@H]5C[C@@H]6[C@@]3(CCC7=C6COC7=O)C)[C@@H]([C@]4(O[C@H]4[C@@H]21)C(C)C)O
CAS DataBase Reference :38748-32-2(CAS DataBase Reference)
EPA Substance Registry System :Trisoxireno[6,7:8a,9:4b,5]phenanthro[1,2-c]furan-1(3H)-one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)-, (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)- (38748-32-2)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Description

Triptolide is the major bioactive constituent of T. wilfordii Hook F., also known as thunder god vine, a traditional Chinese medicinal herb with known antiproliferative, immunosuppressive, anti-inflammatory, antifertility, and anti-polycystic kidney disease effects. Triptolide binds to and inhibits human dCTP pyrophosphatase 1, a “gatekeeper” enzyme that prevents deleterious halogenated nucleotides from entering DNA synthesis, with a Ki value of 168 μM and an IC50 value of 7-10 nM. Triptolide has also been shown to inhibit LPS-stimulated induction of cyclooxygenase 2 mRNA and synthesis of prostaglandin E2 in human peripheral blood monocytes, rheumatoid arthritis synovial fibroblasts, and human neonatal foreskin fibroblasts with an IC50 value of 0.04 μM.

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