12-OAHSA
- CAS No.
- 101901-73-9
- Chemical Name:
- 12-OAHSA
- Synonyms
- 12-OAHSA;OCHJVQODRYVDAA-YPKPFQOOSA-N;9-Octadecenoic acid (9Z)-, 11-carboxy-1-hexylundecyl ester
- CBNumber:
- CB03152432
- Molecular Formula:
- C36H68O4
- Molecular Weight:
- 564.92
- MDL Number:
- MOL File:
- 101901-73-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 12-OAHSA ≥95% | 17108 | 1mg | $69 |
| 12-OAHSA ≥95% | 17108 | 5mg | $297 |
| 12-OAHSA ≥95% | 17108 | 10mg | $525 |
| 12-OAHSA ≥95% | 17108 | 1mg | $62 |
| 12-OAHSA ≥95% | 17108 | 5mg | $270 |
| More product size | |||
12-OAHSA price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17108 | 12-OAHSA ≥95% | 101901-73-9 | 1mg | $69 | 2026-04-30 | Buy |
| Cayman Chemical | 17108 | 12-OAHSA ≥95% | 101901-73-9 | 5mg | $297 | 2026-04-30 | Buy |
| Cayman Chemical | 17108 | 12-OAHSA ≥95% | 101901-73-9 | 10mg | $525 | 2026-04-30 | Buy |
| Cayman Chemical | 17108 | 12-OAHSA ≥95% | 101901-73-9 | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 17108 | 12-OAHSA ≥95% | 101901-73-9 | 5mg | $270 | 2024-03-01 | Buy |
12-OAHSA Chemical Properties,Uses,Production
Uses
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 12-OAHSA is a FAHFA in which oleic acid is esterified at the 12th carbon of hydroxy stearic acid. Among the FAHFA family members, OAHSAs are the most abundantly expressed in the serum of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.[Cayman Chemical]
Definition
ChEBI: 12-[(9Z)-octadecenoyloxy]octadecanoic acid is a fatty acid ester obtained by formal condensation of the carboxy group of oleic acid with the hydroxy group of 12-hydroxyoctadecanoic acid. It is a fatty acid ester and a monocarboxylic acid. It is functionally related to an oleic acid and a 12-hydroxyoctadecanoic acid. It is a conjugate acid of a 12-[(9Z)-octadecenoyloxy]octadecanoate.
in vivo
12-OAHSA (30 mg/kg, p.o., for 10 d) inhibits obesity-induced insulin resistance in HFD induced obese C57BL/6 mice[1].
| Animal Model: | 10-week HFD induced obese C57BL/6 mice[1] |
| Dosage: | 30 mg/kg |
| Administration: | p.o., for 10 d |
| Result: | Decreased adipose tissue macrophage (ATMs), and CD4+ and CD8+ T lymphocytes in eWAT. Inhibits obesity-induced adipose tissue inflammation. |
12-OAHSA Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6777 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11972 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29869 | 58 |
| Cayman Chemical Company | -- | sales@caymanchem.com | China | 6838 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | -- | sales@biosynth.com | China | 6051 | 58 |
| Guangzhou Chuangze Biotechnology Co., Ltd. | -- | CHINA | 6078 | 58 | |
| Chongqing Boer Biotechnology Co., Ltd. | -- | CHINA | 6057 | 58 | |
| Guangzhou Squirrel Biotechnology Co., Ltd. | -- | CHINA | 6609 | 58 |
