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ChemicalBook >> CAS DataBase List >>S-Methyl methanethiolsulfonate

S-Methyl methanethiolsulfonate

CAS No.
2949-92-0
Chemical Name:
S-Methyl methanethiolsulfonate
Synonyms
S-METHYL METHANETHIOSULFONATE;S-Methyl methanesulfonothioate;METHYL METHANETHIOLSULFONATE;S-METHYL METHANETHIOSULPHONATE;METHYL METHANETHIOSULFONATE;(methanesulfonylsulfanyl)methane;METHANETHIOSULFONIC ACID S-METHYL ESTER;NSC 21545;dimethyl thiosulfonate;Neticonazole Impurity 14
CBNumber:
CB0331614
Molecular Formula:
C2H6O2S2
Molecular Weight:
126.2
MDL Number:
MFCD00007565
MOL File:
2949-92-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-16 21:18:09
Product description Number Pack Size Price
S-Methyl methanethiosulfonate 97% 208795 1g $46.9
S-Methyl methanethiosulfonate 97% 208795 10g $255
S-Methyl Methanethiosulfonate >97.0%(GC) M1382 5g $68
S-Methyl Methanethiosulfonate >97.0%(GC) M1382 25g $224
Methyl Methanethiosulfonate (MMTS) ≥95% M3510-60 100mg $355
More product size

S-Methyl methanethiolsulfonate Properties

Melting point 117.0-119.0 °C
Boiling point 69-71 °C0.4 mm Hg(lit.)
Density 1.337 g/mL at 25 °C(lit.)
refractive index n20/D 1.513(lit.)
FLAVIS Number 12.159 | Methyl methanethiosulfonate
Flash point 190 °F
storage temp. 2-8°C
solubility chloroform: soluble750mg + 5 ml Chloroformmg/mL, colorless to light greenish-yellow
form clear liquid
color Colorless to Red to Green
Odor at 0.10 % in propylene glycol. sulfurous pungent roasted
Odor Type sulfurous
BRN 1446059
Stability Water Sensitive
Major Application cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
InChI 1S/C2H6O2S2/c1-5-6(2,3)4/h1-2H3
InChIKey XYONNSVDNIRXKZ-UHFFFAOYSA-N
SMILES CSS(C)(=O)=O
LogP 0.247 (est)
CAS DataBase Reference 2949-92-0(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 0906Z2356U
NIST Chemistry Reference S-methyl methanethiosulphonate(2949-92-0)
EPA Substance Registry System Methanesulfonothioic acid, S-methyl ester (2949-92-0)
UNSPSC Code 12352200
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Exclamation Mark (GHS07)
GHS06,GHS07
Signal word  Danger
Hazard statements  H227-H301+H311+H331-H315-H319
Precautionary statements  P210-P261-P264-P270-P271-P280-P301+P310+P330-P302+P352+P312+P361+P364-P304+P340+P311-P305+P351+P338+P337+P313-P403+P233-P405-P501
Hazard Codes  Xi,Xn
Risk Statements  36-36/37/38-20/21/22
Safety Statements  26-36/37/39
RIDADR  3334
WGK Germany  2
RTECS  PB2765000
13
TSCA  TSCA listed
HazardClass  IRRITANT
PackingGroup  III
HS Code  29309090
Storage Class 10 - Combustible liquids
Toxicity mouse,LD50,intraperitoneal,9110ug/kg (9.11mg/kg),Toxicology and Applied Pharmacology. Vol. 72, Pg. 513, 1984.
NFPA 704
2
2 0

S-Methyl methanethiolsulfonate price More Price(41)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 208795 S-Methyl methanethiosulfonate 97% 2949-92-0 1g $46.9 2026-04-30 Buy
Sigma-Aldrich 208795 S-Methyl methanethiosulfonate 97% 2949-92-0 10g $255 2026-04-30 Buy
TCI Chemical M1382 S-Methyl Methanethiosulfonate >97.0%(GC) 2949-92-0 5g $68 2026-04-30 Buy
TCI Chemical M1382 S-Methyl Methanethiosulfonate >97.0%(GC) 2949-92-0 25g $224 2026-04-30 Buy
Usbiological M3510-60 Methyl Methanethiosulfonate (MMTS) ≥95% 2949-92-0 100mg $355 2026-06-03 Buy
Product number Packaging Price Buy
208795 1g $46.9 Buy
208795 10g $255 Buy
M1382 5g $68 Buy
M1382 25g $224 Buy
M3510-60 100mg $355 Buy

S-Methyl methanethiolsulfonate Chemical Properties,Uses,Production

Chemical Properties

Light Yellow Liquid

Uses

S-Methyl methanethiosulfonate was used as sulfenylating agent for β-keto sulfoxides, methylene compounds, half-esters of malonic acids and aryl Grignard reagents. It was also used as a reagent to trap the natural thiol-disulfide state of the proteins.

Uses

S-Methyl methanethiolsulfonate is used for the rapid and selective modification of sulfhydryl groups of enzymes and it is also useful for mapping the pore-lining regions of the ryanodine receptor.

Uses

carbonyl reactive homobifunctional cross-linking reagent cleavable with periodate

Definition

ChEBI: A sulfonic acid derivative obtained by condensaton of methanesulfonic acid with methanethiol.

Synthesis Reference(s)

The Journal of Organic Chemistry, 49, p. 2281, 1984 DOI: 10.1021/jo00186a039
Synthetic Communications, 20, p. 365, 1990 DOI: 10.1080/00397919008052777

General Description

Interaction of S-methyl methanethiosulfonate (MMTS) with dipalmitoylphosphatidylcholine (DPPC) bilayers has been investigated by FTIR and surface-enhanced Raman spectroscopy.

Purification Methods

Purify it by fractional distillation under reduced pressure, IR: 1350, 750 cm-1 . [Applegate et al. J Org Chem 38 943 1973, Beilstein 4 IV 31.]

Global( 228)Suppliers
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View Lastest Price from S-Methyl methanethiolsulfonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
S-Methyl methanesulfonothioate pictures 2026-06-16 S-Methyl methanesulfonothioate
2949-92-0
99.59% 10g TargetMol Chemicals Inc.
MMTS [Methyl methanethiolsulfonate] pictures 2025-06-07 MMTS [Methyl methanethiolsulfonate]
2949-92-0
100g >95.00% 100g Xian confluore Biological Technology Co., Ltd.
S-Methyl methanethiolsulfonate pictures 2025-04-04 S-Methyl methanethiolsulfonate
2949-92-0
1kg 98% 10Ton Henan Aochuang Chemical Co.,Ltd.
S-Methyl thiomethanesuphonate 4-methyl-2-amino-1,3-thiazole Methanethiosulfonylmethyl Methyl(methylsulfonyl) sulfide Methyl(methylthio) sulfone S-Methyl methanethiolsulfonate,97% 5-METHYLMETHANETHIONSULFONATE NSC 21545 ThioMethanesulfonic Acid S-Methyl Ester Methyl Methanothiosulfonate S-Methyl methanesulphonothioate S-Methyl methanethiosulfonate,S-Methyl thiomethanesulfonate, MMTS S-Methyl Methanethiosulfonate 97% S-Methyl Methanethiosulfonate puruM, >=98.0% (GC) S-METHYL THIOMETHANESULFONATE S-METHYL METHANETHIOLSULFONATE S-METHYL METHANETHIONSULFONATE dimethyl thiosulfonate Methanesulfonic acid, thio-, S-methyl ester Methanesulfonothioic acid, S-methyl ester methanesulfonothioicacid,s-methylester Methyl methanesulfonothioate methylmethanesulfonothioate S-methyl methylthiosulfonate s-methylmethanesulfonothioate thio-methanesulfonicacis-methylester S-Methylemethanethiolsulfonate S-Methylmethanthiosulfonat S-MethylMethanethiosulfonate> Neticonazole Impurity 14 MMTS [Methyl methanethiolsulfonate (methanesulfonylsulfanyl)methane METHYL METHANETHIOSULFONATE S-Methyl methanethiosulfonate METHANETHIOSULFONIC ACID S-METHYL ESTER METHYL METHANETHIOLSULFONATE S-METHYL METHANETHIOSULFONATE S-METHYL METHANETHIOSULPHONATE S-Methyl methanesulfonothioate 2949-92-0 C2H6O2S2 C2H6S2O2 CH3SO2SCH3 Sulfonates/Sulfinates Sulfur Compounds Organic Building Blocks Sulfur Compounds (for Synthesis) Building Blocks Small molecule MTS and Sulfhydryl Active Reagents Sulfur Compounds (for Synthesis) Synthetic Organic Chemistry MTS & Sulfhydryl Active Reagents
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