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ChemicalBook >> CAS DataBase List >>2-CHLOROETHOXY ACETIC ACID

2-CHLOROETHOXY ACETIC ACID

CAS No.
14869-41-1
Chemical Name:
2-CHLOROETHOXY ACETIC ACID
Synonyms
2-(2-chloroethoxy)acetic acid;CAS_14869-41-1;Chloro-PEG-CH2COOH;Chloro-PEG1-CH2COOH;2-CHLOROETHOXY ACETIC ACID;2-(2-Chloroethoxy)aceticaci;5-Chloro-3-oxapentanoic acid;2-(Chloroethoxyl)acetic acid;2-(2-Chloroethoxy)acetic Acid 2;(2-Chloroethoxy)acetic acid 97%
CBNumber:
CB0342386
Molecular Formula:
C4H7ClO3
Molecular Weight:
138.55
MDL Number:
MFCD17014832
MOL File:
14869-41-1.mol
MSDS File:
SDS
Last updated:2026-05-27 17:39:29
Product description Number Pack Size Price
2-Chloroethoxyacetic Acid TRC-C365765-1G 1g $189
2-Chloroethoxyacetic Acid TRC-C365765-10G 10g $1501
2-Chloroethoxyacetic Acid 006248 1g $446
(2-Chloroethoxy)acetic acid 95% OR301184 50mg $21
(2-Chloroethoxy)acetic acid 95% OR301184 1g $78
More product size

2-CHLOROETHOXY ACETIC ACID Properties

Melting point 32.5-33.0 °C
Boiling point 130 °C(Press: 3.5 Torr)
Density 1.3296 g/cm3
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
pka 3.34±0.10(Predicted)
form liquid
color Yellow
InChI InChI=1S/C4H7ClO3/c5-1-2-8-3-4(6)7/h1-3H2,(H,6,7)
InChIKey MHXJETVNZPUVEN-UHFFFAOYSA-N
SMILES C(O)(=O)COCCCl

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H302+H312+H332-H314
Precautionary statements  P260-P280-P362+P364
HS Code  2918999090

2-CHLOROETHOXY ACETIC ACID price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-C365765-1G 2-Chloroethoxyacetic Acid 14869-41-1 1g $189 2026-06-03 Buy
TRC TRC-C365765-10G 2-Chloroethoxyacetic Acid 14869-41-1 10g $1501 2026-06-03 Buy
Usbiological 006248 2-Chloroethoxyacetic Acid 14869-41-1 1g $446 2026-06-03 Buy
Apolloscientific OR301184 (2-Chloroethoxy)acetic acid 95% 14869-41-1 50mg $21 2026-06-04 Buy
Apolloscientific OR301184 (2-Chloroethoxy)acetic acid 95% 14869-41-1 1g $78 2026-06-04 Buy
Product number Packaging Price Buy
TRC-C365765-1G 1g $189 Buy
TRC-C365765-10G 10g $1501 Buy
006248 1g $446 Buy
OR301184 50mg $21 Buy
OR301184 1g $78 Buy

2-CHLOROETHOXY ACETIC ACID Chemical Properties,Uses,Production

Chemical Properties

Light Yellow Oil

Uses

A metabolite of Bis(2-chloroethyl) Ether.

Synthesis

2-(2-Chloroethoxy)ethanol

628-89-7

2-CHLOROETHOXY ACETIC ACID

14869-41-1

The general procedure for the synthesis of 2-(2-chloroethoxy)acetic acid from 2-chloroethoxyethanol was as follows: ethylene glycol mono-2-chloroethyl ether (10 g, 0.08 mol) was mixed with a 30% aqueous hydrogen peroxide solution (22.8 g, 0.2 mol), followed by the addition of sodium sulfate dihydrate (0.53 g, 1.6 mmol) and tri-octylmethyl ammonium sulfate (0.75 g, 1.6 mmol). The reaction mixture was stirred at 90°C for 4 hours. Upon completion of the reaction, the reaction was quenched by the addition of aqueous sodium thiosulfate, and then the mixture was extracted with ethyl acetate (50 mL). The organic layers were combined, washed sequentially with water and saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give an oily residue (9 g). The residue was diluted with ether and filtered to remove insoluble impurities. The filtrate was extracted by partitioning with the addition of aqueous sodium bicarbonate. The aqueous layer was washed with ether, acidified to pH 2-3 with dilute hydrochloric acid and extracted with ethyl acetate. The organic layers were combined, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to give 2-(2-chloroethoxy)acetic acid crude (2.14 g, 19.3% yield) as an oil.IR (neat): ν = 3410 (O-H), 1727 (C=O), 1123, 1044 cm1 .

References

[1] Tetrahedron Letters, 1996, vol. 37, # 28, p. 4837 - 4840
[2] Heterocycles, 2007, vol. 74, # C, p. 437 - 445
[3] Organic and Biomolecular Chemistry, 2016, vol. 14, # 16, p. 3950 - 3955
[4] Patent: EP1640373, 2006, A1. Location in patent: Page/Page column 21
[5] Patent: WO2008/75152, 2008, A1. Location in patent: Page/Page column 40-41

628-89-7
14869-41-1
Synthesis of 2-CHLOROETHOXY ACETIC ACID from 2-(2-Chloroethoxy)ethanol
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View Lastest Price from 2-CHLOROETHOXY ACETIC ACID manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-CHLOROETHOXY ACETIC ACID pictures 2026-07-26 2-CHLOROETHOXY ACETIC ACID
14869-41-1
0.99 RongNa Biotechnology Co.,Ltd
2-CHLOROETHOXY ACETIC ACID pictures 2019-07-06 2-CHLOROETHOXY ACETIC ACID
14869-41-1
$1.00 1KG 98% 100KG Career Henan Chemical Co
Acetic acid, 2-(2-chloroethoxy)- 2-(Chloroethoxyl)acetic acid 2-CHLOROETHOXY ACETIC ACID 5-Chloro-3-oxapentanoic acid Chloro-PEG-CH2COOH (2-Chloroethoxy)acetic acid 97% CAS_14869-41-1 Chloro-PEG1-CH2COOH 2-(2-Chloroethoxy)acetic Acid 2 2-(2-Chloroethoxy)aceticaci 2-(2-chloroethoxy)acetic acid 14869-41-1
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