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ChemicalBook >> CAS DataBase List >>Sulbactam sodium

Sulbactam sodium

CAS No.
69388-84-7
Chemical Name:
Sulbactam sodium
Synonyms
Sodium Sodium;SODIUM SULBACTAM;Sulbatam Sodium;Sterile Sulbactam sodium;(2S,5R);CP-45899-2;Shu ba sodium;sulbacyam sodium;SULBACTAM SODIUM;cp45899sodiumsalt
CBNumber:
CB0370356
Molecular Formula:
C8H12NNaO5S
Molecular Weight:
257.24
MDL Number:
MFCD01750374
MOL File:
69388-84-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
Product description Number Pack Size Price
Sulbactam sodium European Pharmacopoeia (EP) Reference Standard Y0000529 10 mg $241
Sulbactam sodium ≥98% (HPLC), powder, β-lactamase inhibitor SML4181 50 mg $117
Sulbactam sodium ≥98% (HPLC) SML4181 1 unit $109
Sulbactam sodium European Pharmacopoeia (EP) Reference Standard Y0000529 y0000529 $220
Sulbactam Sodium U0159 1G $104
More product size

Sulbactam sodium Properties

Melting point >230°C (dec.)
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility Freely soluble in water, sparingly soluble in ethyl acetate, very slightly soluble in ethanol (96 per cent). It is freely soluble in dilute acids.
form Solid
color White
InChI InChI=1/C8H11NO5S.Na.H/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14;;/h5-6H,3H2,1-2H3,(H,11,12);;/t5-,6+;;/s3
InChIKey NKZMPZCWBSWAOX-IBTYICNHSA-M
SMILES C([C@H]1C(S(=O)(=O)[C@]2([H])CC(=O)N12)(C)C)(=O)O.[NaH] |&1:1,6,r|
CAS DataBase Reference 69388-84-7(CAS DataBase Reference)
FDA UNII DKQ4T82YE6
NACRES NA.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard Codes  Xn
Risk Statements  42/43
Safety Statements  22-24-36/37-45-24/25
HS Code  29349990
Toxicity LD50 ivn-rat: 6500 mg/kg NKRZAZ 32(Suppl 4),97,84

Sulbactam sodium price More Price(81)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000529 Sulbactam sodium European Pharmacopoeia (EP) Reference Standard 69388-84-7 10 mg $241 2026-04-30 Buy
Sigma-Aldrich SML4181 Sulbactam sodium ≥98% (HPLC), powder, β-lactamase inhibitor 69388-84-7 50 mg $117 2026-04-30 Buy
Sigma-Aldrich SML4181 Sulbactam sodium ≥98% (HPLC) 69388-84-7 1 unit $109 2025-07-31 Buy
Sigma-Aldrich Y0000529 Sulbactam sodium European Pharmacopoeia (EP) Reference Standard 69388-84-7 y0000529 $220 2024-03-01 Buy
TCI Chemical U0159 Sulbactam Sodium 69388-84-7 1G $104 2026-04-30 Buy
Product number Packaging Price Buy
Y0000529 10 mg $241 Buy
SML4181 50 mg $117 Buy
SML4181 1 unit $109 Buy
Y0000529 y0000529 $220 Buy
U0159 1G $104 Buy

Sulbactam sodium Chemical Properties,Uses,Production

Description

Sulbactam sodium is a parenterally-active, β-lactamase inhibitor recently introduced as a 1: 1 combination product with cefoperazone. Like clavulanic acid, the first agent of this type to b e introduced, sulbactam enhances the effectiveness of β-lactam antibiotics against resistant strains.

Chemical Properties

White Solid

Originator

Pfizer (USA)

Uses

A semi-synthetic β-lactamase inhibitor. It is used in combination with β-lactam antibiotics as antibacterial.

Definition

ChEBI: Sulbactam sodium is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.

Manufacturing Process

Sulbactam sodium is semi-synthetic antibiotic of penicillinic group. Start material for it's synthesis is 6-aminopenicillanic acid. First 6-aminopenicillanic acid was isolated in 1957 year from benzylpenicilline as resalt of treating of it by penicillinaze. Benzylpenicilline is produced by microorganism of genus Streptomyces.
Further, 6-aminopenicillanic acid reacted with bromine, hydrochloric acid and NaNO2. As a result the 6,6-dibromopenicillanic acid was obtained.
6,6-Dibromopenicillanic acid was oxidized by KMnO4, to give 6,6-dibromo-1,1-The 6,6-dibromo-1,1-dioxopenicillanic acid in presence of Fe was converted to the 1,1-dioxopenicillanic acid (sulbactam acid). The sulbactam acid was treated by sodium 2-ethylhexanoate and crude sulbactam sodium was obtained.

brand name

SULPERAZONE

Therapeutic Function

Beta-lactamase inhibitor

General Description

Sulbactam was synthesized by Pfizer Research Laboratories in 1977 in the course of screening for β-lactamase inhibitors. It shows strong activity against penicillinase and moderate activity against cephalosporinase. Sulbactam itself shows activity against some gramnegative bacteria but no activity against most pathogenic bacteria. The use of sulbactam in combination with cefoperazone, which is partially hydrolyzed by penicillinase, is under study along with its use as an esterified complex with ampicillin (sultamicillin) for therapy of cefoperazone-ampicillin-resistant infections.

Safety Profile

Poison by intravenous route. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx

Sulbactam sodium Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 461)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+86-15350571055 Sibel@chuanghaibio.com China 8738 58
Wuhan Fortuna Chemical Co., Ltd 		+86-27-59207850 info@fortunachem.com China 5997 58
Hebei Chuanghai Biotechnology Co., Ltd 		+86-17732866630 mina@chuanghaibio.com China 18126 58
shandong perfect biotechnology co.ltd 		+86-53169958659 +86-13153181156 sales@sdperfect.com China 294 58
Hangzhou ICH Biofarm Co., Ltd 		+86-0571-28186870; +undefined8613073685410 sales@ichemie.com China 1006 58
Hangzhou Hyper Chemicals Limited 		+86-0086-57187702781 +86-13675893055 info@hyper-chem.com China 310 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 		sarah@tnjone.com China 1143 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 niki@zlchemi.com China 7245 58
Sinoway Industrial co., ltd. 		+86-0592-5800732 +86-13806035118 xie@china-sinoway.com China 1369 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21585 55

View Lastest Price from Sulbactam sodium manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sulbactam sodium pictures 2026-07-29 Sulbactam sodium
69388-84-7
 1kg 99% 20tons Sinoway Industrial co., ltd.
Sulbactam sodium pictures 2026-07-29 Sulbactam sodium
69388-84-7
 10KG 98%min, sterile or non-sterile, USP 500kg WUHAN FORTUNA CHEMICAL CO., LTD
Sulbactam Sodium pictures 2026-07-28 Sulbactam Sodium
69388-84-7
 1KG USP 5,000KG Hangzhou Hyper Chemicals Limited
  • Sulbactam sodium pictures
  • Sulbactam sodium
    69388-84-7
  • $0.00
  • 98%min, sterile or non-sterile, USP
  • WUHAN FORTUNA CHEMICAL CO., LTD
SULBACTAM SODIUM SULBACTAM SODIUM SALT sodium (2s-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, sodium salt, (2S,5R)- (9CI) (2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3,2,0]heptane-2-carboxylic acid 4,4-dioxide sodium salt sodium (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide sulbacyam sodium AMPICILLIN SODIUM AND SULBACTAM SODIUM 2:1 CP-45899-2 Penicillanic acid 4,4-dioxide sodium salt Sterile Sulbactum Sodium Powder SulbactaM SodiuM, USP (2S,5R) SulbactaM SodiuM API 3,3-dimethyl-7-oxo-4,4-dioxide-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, sodium salt (1:1) 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,3,3-dimethyl-7-oxo-,4,4-d cp45899sodiumsalt penicillanicacid1,1-dioxidesodiumsalt penicillanicaciddioxidesodiumsalt penicillanicacidsulfonesodiumsalt sodium1,1-dioxopenicillanate sodiumpenicillanate1,1-dioxide sodiumsalt,(2s-cis)-ioxid Sulbactam sodium USP/EP/BP Sulbactam sodiumQ: What is Sulbactam sodium Q: What is the CAS Number of Sulbactam sodium Q: What is the storage condition of Sulbactam sodium Q: What are the applications of Sulbactam sodium Antibiotic medicine CAS 69388-84-7 veterinary sulbactam sodium sodium 3,3-dimethyl-4,4,7-trioxo-4$l^{6}-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Sulbactam sodium - CP 45899 sodium Sulbactam sodium CRS Sulbatam Sodium Sodium Sodium Sterile Sulbactam sodium Shu ba sodium Natrium-(2S-cis)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carboxylat-4,4-dioxid Sulbactam Sodium (100 mg) Sulbactam sodium salt, beta-lactamase inhibitor Sulbactam sodium, 10 mM in DMSO SULBACTAM SODIUM USP (NON-STERILE BULK) (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacidsodiumsalt4,4-dioxide SODIUM SULBACTAM 69388-84-7 C8H10NNaO5S C8H10NO5SNa 25522 pharmaceutical raw material Antibiotic Pharmaceutical raw materials Inhibitors Pharma Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Sulfur & Selenium Compounds API APIs 69388-84-7
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