1-PHENYL-2-PROPYN-1-OL
- CAS No.
- 4187-87-5
- Chemical Name:
- 1-PHENYL-2-PROPYN-1-OL
- Synonyms
- PHENYLETHYNYLCARBINOL;ETHYNYLPHENYLCARBINOL;1-PHENYL-PROP-2-YN-1-OL;Phenylpropynol;Phenyl-2-propy;TIMTEC-BB SBB008986;1-PHENYL-2-PROPYN-1-OL;1-PHENYL-2-PROPYNE-1-OL;à-ethynylbenzyl alcohol;2-Propyn-1-ol, 1-phenyl-
- CBNumber:
- CB0409973
- Molecular Formula:
- C9H8O
- Molecular Weight:
- 132.16
- MDL Number:
- MFCD00021860
- MOL File:
- 4187-87-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Phenyl-2-propyn-1-ol 98% | 226610 | 1g | $27.5 |
| 1-Phenyl-2-propyn-1-ol 98% | 226610 | 10g | $198 |
| 1-Phenyl-2-propyn-1-ol >98.0%(GC) | P0220 | 5g | $73 |
| 1-Phenyl-2-propyn-1-ol >98.0%(GC) | P0220 | 25g | $278 |
| 1-Phenyl-2-propyn-1-ol | TRC-P336418-500MG | 500mg | $91 |
| More product size | |||
| Melting point | 22-23 °C(lit.) |
|---|---|
| Boiling point | 135-136 °C13 mm Hg(lit.) |
| alpha | 0°(neat) |
| Density | 1.087 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 211 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | 12.40±0.20(Predicted) |
| form | Liquid |
| color | Clear yellow |
| Specific Gravity | 1.087 |
| BRN | 742365 |
| InChI | 1S/C9H8O/c1-2-9(10)8-6-4-3-5-7-8/h1,3-7,9-10H |
| InChIKey | UIGLAZDLBZDVBL-UHFFFAOYSA-N |
| SMILES | OC(C#C)c1ccccc1 |
| CAS DataBase Reference | 4187-87-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| RIDADR | UN2810 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DO5900000 | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29062990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Toxicity | mouse,LD50,intraperitoneal,240mg/kg (240mg/kg),Farmaco, Edizione Scientifica. Vol. 8, Pg. 406, 1953. | |||||||||
| NFPA 704 |
|
1-PHENYL-2-PROPYN-1-OL price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 226610 | 1-Phenyl-2-propyn-1-ol 98% | 4187-87-5 | 1g | $27.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 226610 | 1-Phenyl-2-propyn-1-ol 98% | 4187-87-5 | 10g | $198 | 2026-04-30 | Buy |
| TCI Chemical | P0220 | 1-Phenyl-2-propyn-1-ol >98.0%(GC) | 4187-87-5 | 5g | $73 | 2026-04-30 | Buy |
| TCI Chemical | P0220 | 1-Phenyl-2-propyn-1-ol >98.0%(GC) | 4187-87-5 | 25g | $278 | 2026-04-30 | Buy |
| TRC | TRC-P336418-500MG | 1-Phenyl-2-propyn-1-ol | 4187-87-5 | 500mg | $91 | 2026-06-03 | Buy |
1-PHENYL-2-PROPYN-1-OL Chemical Properties,Uses,Production
Chemical Properties
Clear yellow liquid
Synthesis
100-52-7
74-86-2
4187-87-5
The general procedure for the synthesis of (±)-1-phenyl-2-propyn-1-ol from benzaldehyde and acetylene was as follows: magnesium (518 mg, 28.3 mmol) was placed in a pre-flame-dried, two-necked, round-bottomed flask fitted with a reflux condenser and cooled to room temperature under argon atmosphere. Subsequently, tetrahydrofuran (30 mL) and a small amount of iodine crystals were added. Next, a portion of the total volume of n-butyl chloride (2.23 mL, 28.3 mmol) was added dropwise and the mixture was refluxed until the Grignard reagent was generated. After removing the unreacted n-butyl chloride, the remaining n-butyl chloride was added. Stirring was continued at room temperature until all the magnesium was consumed. The reaction mixture was cooled to 0°C and acetylene gas was passed into it over a period of 15 minutes. Subsequently, benzaldehyde (1.0 g, 9.4 mmol) dissolved in tetrahydrofuran (20 mL) was added at 0°C and stirred for 6 hours. Upon completion of the reaction, the reaction was quenched with saturated ammonium chloride solution, diluted with water and extracted with ethyl acetate. The organic layers were combined, dried with anhydrous sodium sulfate, concentrated and purified by silica gel column chromatography (eluent 10% petroleum ether solution of ethyl acetate) to afford the target product (±)-1-phenyl-2-propyn-1-ol (1.08 g, 86% yield) as a pale yellow oil.
References
[1] Liebigs Annalen der Chemie, 1982, # 9, p. 1750 - 1752
[2] Organic and Biomolecular Chemistry, 2013, vol. 11, # 35, p. 5954 - 5962
[3] Patent: WO2015/193915, 2015, A1. Location in patent: Page/Page column 11
[4] Liebigs Annalen, 1995, # 7, p. 1353 - 1360
[5] Synthesis, 2004, # 9, p. 1381 - 1390
1-PHENYL-2-PROPYN-1-OL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 17389186172 | 1077@dideu.com | China | 3796 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8828 | 58 |
View Lastest Price from 1-PHENYL-2-PROPYN-1-OL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 1-PHENYL-2-PROPYN-1-OL
4187-87-5
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-12-12 | 1-PHENYL-2-PROPYN-1-OL
4187-87-5
|
$1.00-35.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd | |
 |
2022-01-04 | 1-Phenyl-2-propyn-1-ol
4187-87-5
|
1g | 98%min | 100kgs/month | Shanghai Rlavie Technology Co ltd |
-
- 1-PHENYL-2-PROPYN-1-OL
4187-87-5
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 1-PHENYL-2-PROPYN-1-OL
4187-87-5
- $1.00-35.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 1-Phenyl-2-propyn-1-ol
4187-87-5
- 98%min
- Shanghai Rlavie Technology Co ltd
