Methyl 4-amino-3-bromobenzoate
- CAS No.
- 106896-49-5
- Chemical Name:
- Methyl 4-amino-3-bromobenzoate
- Synonyms
- 4-aMino-3-broMobenzoate;Methyl 4-amino-3-bromoben;METHYL 4-AMINO-3-BROMOBENZOATE;Methyl-3-bromo-4-aminobenzoate;Methyl4-Amino-3-bromobenzoate>2-Bromo-4-(methoxycarbonyl)aniline;Methyl 4-amino-3-bromobenzoate,98%;Methyl 4-amino-3-bromobenzoate 98%;Methyl 4-amino-3-bromobenzoate, GC 98%;4-AMINO-3-BROMO-BENZOIC ACID METHYL ESTER
- CBNumber:
- CB0482291
- Molecular Formula:
- C8H8BrNO2
- Molecular Weight:
- 230.06
- MDL Number:
- MFCD01861385
- MOL File:
- 106896-49-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 4-amino-3-bromobenzoate 97% | 655910 | 5g | $128 |
| Methyl 4-amino-3-bromobenzoate 97% | 655910 | 1g | $53.8 |
| Methyl 4-Amino-3-bromobenzoate >98.0%(GC) | M2084 | 1g | $26 |
| Methyl 4-Amino-3-bromobenzoate >98.0%(GC) | M2084 | 5g | $92 |
| Methyl 4-amino-3-bromobenzoate Asreported | 283489 | 1g | $358 |
| More product size | |||
| Melting point | 105-109 °C |
|---|---|
| Boiling point | 334.2±22.0 °C(Predicted) |
| Density | 1.6270 (rough estimate) |
| refractive index | 1.6120 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 0.41±0.10(Predicted) |
| form | Crystalline Powder |
| color | Brown |
| InChI | InChI=1S/C8H8BrNO2/c1-12-8(11)5-2-3-7(10)6(9)4-5/h2-4H,10H2,1H3 |
| InChIKey | AIUWAOALZYWQBX-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC=C(N)C(Br)=C1 |
| CAS DataBase Reference | 106896-49-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H319 | |||||||||
| Precautionary statements | P301+P310+P330-P305+P351+P338 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36-36/37/38 | |||||||||
| Safety Statements | 26-36/37-37/39 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29163100 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 |
|||||||||
| NFPA 704 |
|
Methyl 4-amino-3-bromobenzoate price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 655910 | Methyl 4-amino-3-bromobenzoate 97% | 106896-49-5 | 5g | $128 | 2026-04-30 | Buy |
| Sigma-Aldrich | 655910 | Methyl 4-amino-3-bromobenzoate 97% | 106896-49-5 | 1g | $53.8 | 2023-06-20 | Buy |
| TCI Chemical | M2084 | Methyl 4-Amino-3-bromobenzoate >98.0%(GC) | 106896-49-5 | 1g | $26 | 2026-04-30 | Buy |
| TCI Chemical | M2084 | Methyl 4-Amino-3-bromobenzoate >98.0%(GC) | 106896-49-5 | 5g | $92 | 2026-04-30 | Buy |
| Usbiological | 283489 | Methyl 4-amino-3-bromobenzoate Asreported | 106896-49-5 | 1g | $358 | 2026-06-03 | Buy |
Methyl 4-amino-3-bromobenzoate Chemical Properties,Uses,Production
Uses
Methyl 4-amino-3-bromobenzoate is a carboxylic acid derivative and a commonly used pharmaceutical and chemical intermediate.
Chemical Properties
brown crystalline powder
Synthesis
619-45-4
106896-49-5
General procedure for the preparation of methyl 4-amino-3-bromobenzoate: methyl 4-aminobenzoate (17 g, 0.1 mol) was dissolved in chloroform (250 mL). N-bromosuccinimide (20 g, 0.1 mol) was added slowly at 0 °C and the reaction mixture was stirred continuously for 3 h at this temperature. After completion of the reaction, the solvent was removed by distillation. Ethyl acetate (100 mL) was added to the residue for dissolution. Subsequently, the mixture was washed with aqueous sodium chloride to remove water-soluble impurities. The organic layer was separated and dried with anhydrous magnesium sulfate. After filtration, the product was purified by recrystallization from hexane to give the final methyl 4-amino-3-bromobenzoate (24.3 g, 93% yield). [1368] NMR data: 1H-NMR (CDCl3) δ 8.11 (1H, d), 7.79-7.77 (1H, m), 6.72 (1H, d), 4.51 (2H, br s), 3.85 (3H, s).
References
[1] Journal of Organic Chemistry, 2014, vol. 79, # 21, p. 10410 - 10416
[2] Patent: WO2010/93191, 2010, A2. Location in patent: Paragraph 1365-1368
[3] Organic Letters, 2015, vol. 17, # 12, p. 2886 - 2889
[4] European Journal of Medicinal Chemistry, 2011, vol. 46, # 7, p. 2930 - 2936
[5] Synthesis (Germany), 2013, vol. 45, # 11, p. 1497 - 1504
Methyl 4-amino-3-bromobenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 | |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
View Lastest Price from Methyl 4-amino-3-bromobenzoate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | Methyl 4-amino-3-bromobenzoate
106896-49-5
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-12 | Methyl 4-amino-3-bromobenzoate
106896-49-5
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- Methyl 4-amino-3-bromobenzoate
106896-49-5
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Methyl 4-amino-3-bromobenzoate
106896-49-5
- $1.00
- 99%
- Career Henan Chemical Co
