L-Malic acid
- CAS No.
- 97-67-6
- Chemical Name:
- L-Malic acid
- Synonyms
- L-MALIC ACID;L-(-)-MALIC ACID;(2S)-2-hydroxybutanedioic acid;L-Malic;apple acid;L-Mailcacid;HYDROXYBUTANEDIOIC ACID;L-Gydroxybutanedioicacid;pinguosuan;(S)-(-)-MALIC ACID
- CBNumber:
- CB0493594
- Molecular Formula:
- C4H6O5
- Molecular Weight:
- 134.09
- MDL Number:
- MFCD00064213
- MOL File:
- 97-67-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| L-(-)-Malic acid for resolution of racemates for synthesis | 8.00384 | 5G | $29.7 |
| L-(-)-Malic acid for resolution of racemates for synthesis | 8.00384 | 10g | $43.4 |
| L-(-)-Malic acid for resolution of racemates for synthesis | 8.00384 | 50g | $109 |
| L-(-)-Malic acid for resolution of racemates for synthesis | 8.00384 | 500g | $449 |
| L-(-)-Malic acid for resolution of racemates for synthesis | 8.00384 | 1kg | $876 |
| More product size | |||
| Melting point | 101-103 °C (lit.) |
|---|---|
| Boiling point | 167.16°C (rough estimate) |
| alpha | -2 º (c=8.5, H2O) |
| Density | 1.60 |
| bulk density | 600kg/m3 |
| vapor pressure | 0Pa at 25℃ |
| refractive index | -6.5 ° (C=10, Acetone) |
| FEMA | 2655 | L-MALIC ACID |
| Flash point | 220 °C |
| storage temp. | Store below +30°C. |
| solubility | H2O: 0.5 M at 20 °C, clear, colorless |
| form | Powder |
| Specific Gravity | 1.595 (20/4℃) |
| color | White |
| PH | 2.2 (10g/l, H2O, 20℃) |
| pka | (1) 3.46, (2) 5.10(at 25℃) |
| Odor | odorless |
| Odor Type | odorless |
| biological source | microbial |
| optical activity | [α]20/D 30±2°, c = 5.5% in pyridine |
| Water Solubility | soluble |
| Merck | 14,5707 |
| JECFA Number | 619 |
| BRN | 1723541 |
| Cosmetics Ingredients Functions | BUFFERING |
| InChI | 1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1 |
| InChIKey | BJEPYKJPYRNKOW-REOHCLBHSA-N |
| SMILES | O[C@@H](CC(O)=O)C(O)=O |
| LogP | -1.68 |
| SCOGS (Select Committee on GRAS Substances) | L-Malic acid |
| CAS DataBase Reference | 97-67-6(CAS DataBase Reference) |
| Substances Added to Food (formerly EAFUS) | L-MALIC ACID |
| FDA UNII | J3TZF807X5 |
| NIST Chemistry Reference | Butanedioic acid, hydroxy-, (s)-(97-67-6) |
| EPA Substance Registry System | Butanedioic acid, 2-hydroxy-, (2S)- (97-67-6) |
| UNSPSC Code | 51113400 |
| NACRES | NA.75 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | ON7175000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29181980 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
L-Malic acid price More Price(123)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 5G | $29.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 10g | $43.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 50g | $109 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 500g | $449 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.00384 | L-(-)-Malic acid for resolution of racemates for synthesis | 97-67-6 | 1kg | $876 | 2026-04-30 | Buy |
L-Malic acid Chemical Properties,Uses,Production
Description
L-Malic acid is nearly odorless (sometimes a faint, acrid odor) with a tart, acidic taste. It is nonpungent. May be prepared by hydration of maleic acid; by fermentation from sugars.
Chemical Properties
L-Malic acid is nearly odorless (sometimes a faint, acrid odor). This compound has a tart, acidic, nonpungent taste.
Chemical Properties
clear colourless solution
Occurrence
Occurs in maple sap, apple, melon, papaya, beer, grape wine, cocoa, sake, kiwifruit and chicory root.
Uses
The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece
Uses
L-Malic acid is used as a food additive, Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists, 1α,25-dihydroxyvitamin D3 analogue, and phoslactomycin B.
Uses
Intermediate in chemical synthesis. Chelating and buffering agent. Flavoring agent, flavor enhancer and acidulant in foods.
Preparation
L-Malic acid can be prepared by hydration of maleic acid; by fermentation from sugar.
Definition
ChEBI: An optically active form of malic acid having (S)-configuration.
General Description
L-Malic acid is an organic acid that is commonly found in wine. It plays an important role in wine microbiological stability.
Biochem/physiol Actions
L-Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. L-Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.
Purification Methods
Crystallise S-malic acid (charcoal) from ethyl acetate/pet ether (b 55-56o), keeping the temperature below 65o. Or dissolve it by refluxing in fifteen parts of anhydrous diethyl ether, decant, concentrate to one-third volume and crystallise it at 0o, repeatedly to constant melting point. [Beilstein 3 IV 1123.]
L-Malic acid Preparation Products And Raw materials
Raw materials
Preparation Products
1of3
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd | 510-85010237 | overseamarketing@alphahi-tech.com | CHINA | 41 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 8834 | 58 |
| Shanghai Hehua Chemical Co.，Ltd | +86-15800509834 +86-15800509834 | sales@hehuachemical.com | China | 121 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 17389186172 | 1077@dideu.com | China | 3796 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-18712993135 | sales01@tairunfaz.com | China | 8051 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 | hbjbtech@163.com | China | 1000 | 58 |
| Chongqing Zhihe Biopharmaceutical Co., Ltd. | +8618580541567 | sales@zhswyy.com | China | 260 | 58 |
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View Lastest Price from L-Malic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-25 | L-(-)-Malic Acid
97-67-6
|
0.99 | RongNa Biotechnology Co.,Ltd | ||||
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2026-07-24 | L-Malic acid
97-67-6
|
$4.00-7.00 | 25g | 0.99 | 100kg | Shanghai UCHEM Inc. | |
 |
2026-07-24 | L-(-)-Malic Acid
97-67-6
|
1KG | 99%min | 1000kgs | WUHAN FORTUNA CHEMICAL CO., LTD |
-
- L-(-)-Malic Acid
97-67-6
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- L-Malic acid
97-67-6
- $4.00-7.00
- 0.99
- Shanghai UCHEM Inc.
-
- L-(-)-Malic Acid
97-67-6
- $0.00
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
