5-(BROMOMETHYL)-2,3-DIHYDRO-1,4-BENZODIOXINE,97%
- CAS No.
- 214894-89-0
- Chemical Name:
- 5-(BROMOMETHYL)-2,3-DIHYDRO-1,4-BENZODIOXINE,97%
- Synonyms
- 5-(bromomethyl)-2,3-dihydro-1,4-Benzodioxin;5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine;1,4-Benzodioxin, 5-(bromomethyl)-2,3-dihydro-;5-(bromomethyl)-2,3-dihydrobenzo[b][1,4]dioxine;5-(BROMOMETHYL)-2,3-DIHYDRO-1,4-BENZODIOXINE,97%
- CBNumber:
- CB0506481
- Molecular Formula:
- C9H9BrO2
- Molecular Weight:
- 229.07
- MDL Number:
- MFCD05664400
- MOL File:
- 214894-89-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine 95% | AS110656 | 1g | $297 |
| 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine 95% | AS110656 | 5g | $1016 |
| 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine | 119091 | 100.00mg | $442 |
| 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine | 119091 | 250.00mg | $706 |
| 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine | 119091 | 1.00g | $1764 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
5-(BROMOMETHYL)-2,3-DIHYDRO-1,4-BENZODIOXINE,97% price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS110656 | 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine 95% | 214894-89-0 | 1g | $297 | 2026-06-04 | Buy |
| Activate Scientific | AS110656 | 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine 95% | 214894-89-0 | 5g | $1016 | 2026-06-04 | Buy |
| Matrix Scientific | 119091 | 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine | 214894-89-0 | 100.00mg | $442 | 2026-05-18 | Buy |
| Matrix Scientific | 119091 | 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine | 214894-89-0 | 250.00mg | $706 | 2026-05-18 | Buy |
| Matrix Scientific | 119091 | 5-(Bromomethyl)-2,3-dihydro-1,4-benzodioxine | 214894-89-0 | 1.00g | $1764 | 2026-05-18 | Buy |
5-(BROMOMETHYL)-2,3-DIHYDRO-1,4-BENZODIOXINE,97% Chemical Properties,Uses,Production
Synthesis
274910-19-9
214894-89-0
The general procedure for the synthesis of 5-bromomethyl-2,3-dihydro-1,4-benzodioxole from (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)methanol was as follows: (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)methanol (3.75 g, 32.3 mmol) was dissolved in ethyl ether (80 mL) and the solution was cooled to 0 °C. Phosphorus tribromide (3.67 mL, 38.8 mmol) was added slowly and dropwise with stirring. The reaction mixture was continued to be stirred at 0 °C for 10 minutes, then brought to room temperature and stirred for 1 hour. Upon completion of the reaction, water (10 mL) was carefully added to quench the excess phosphorus tribromide. The mixture was diluted with ether and washed with water (3 x 50 mL). The combined organic layers were washed with brine (100 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 5-bromomethyl-2,3-dihydro-1,4-benzodioxole as a brown solid (4.61 g, 62% yield). The product was characterized by 1H NMR (CDCl3): δ 6.91-6.77 (m, 3H), 4.52 (s, 2H), 4.35-4.33 (m, 2H), 4.29-4.27 (m, 2H). Mass spectrum measured value: [M + H-Br] = 149.5.
References
[1] Patent: WO2017/155909, 2017, A1. Location in patent: Paragraph 0076
[2] Bioorganic and Medicinal Chemistry, 2018, vol. 26, # 8, p. 1797 - 1809
5-(BROMOMETHYL)-2,3-DIHYDRO-1,4-BENZODIOXINE,97% Preparation Products And Raw materials
Raw materials
Preparation Products
5-(BROMOMETHYL)-2,3-DIHYDRO-1,4-BENZODIOXINE,97% Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| ZHIWE CHEMTECH CO LTD | 021-20221225 13917446399 | zwchem@163.com | China | 575 | 61 |
| Amber MolTech LLC | 086-010-62176588 | amber@jyamber.com | China | 10150 | 56 |
| Zhengzhou Alfachem Co., Ltd. | 0371-53765687 18937137882 | 3969243885@qq.com | China | 7732 | 55 |
| Shanghai TuZhi Chemical Co., Ltd. | 19542790274 | 2119559397@qq.com | China | 748 | 50 |
| Yantai ShengKailun Chemical Technology Co., Ltd. | 13356901049 | 3119594100@qq.com | China | 7964 | 55 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400-6387771-6039 18920764717 | sales@heowns.com | China | 24573 | 60 |
