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Msx1 (P5) Antibody

CAS No.
Chemical Name:
Msx1 (P5) Antibody
Synonyms
Msx1 (P5) Antibody
CBNumber:
CB05744240
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Msx1 (P5) Antibody Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human

Background

Msh homeobox 1 is a Muscle Segment Homeobox gene family member that acts as a transcriptional repressor during embryonic development, playing an important role in limb pattern formation, craniofacial development, and tooth development. Msx1 is expressed in the mesenchyme of the developing nail bed and in fetal hair follicles, epidermis and fibroblasts; reduced expression is seen in adult epithelial-derived tissues. Msx1 acts in concert with the Wnt1 network to establish the midbrain dopaminergic progenator domain, a region that gives rise to neurons that are critical for normal brain function and are the cells affected in Parkinson disease. Mutation in the corresponding Msx1 gene correlates with abnormal tooth development in patients diagnosed with Wolf-Hirschhorn syndrome. Other genetic changes in the Msx1 gene result in Witkop Syndrome and cases of abnormal tooth development associated with non-syndromic orofacial clefting.

References

[1] Jezewski, P.A. et al. (2003) J Med Genet 40, 399-407.
[2] Jumlongras, D. et al. (2001) Am J Hum Genet 69, 67-74.
[3] Lidral, A.C. and Reising, B.C. (2002) J Dent Res 81, 274-8.
[4] Stelnicki, E.J. et al. (1997) Differentiation 62, 33-41.
[5] Andersson, E. et al. (2006) Cell 124, 393-405.
[6] Nieminen, P. et al. (2003) J Dent Res 82, 1013-7.
[7] van den Boogaard, M.J. et al. (2000) Nat Genet 24, 342-3.

Msx1 (P5) Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

Msx1 (P5) Antibody Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Supplier Advantage
Cell Signaling Technology Inc 58
Msx1 (P5) Antibody
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