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Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb

CAS No.
Chemical Name:
Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb
Synonyms
Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb
CBNumber:
CB06277503
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse

Background

TRAFs are a family of multifunctional adaptor proteins that bind to surface receptors and recruit additional proteins to form multiprotein signaling complexes capable of promoting cellular responses. Members of the TRAF family share a common carboxy-terminal "TRAF domain", which mediates interactions with associated proteins; many also contain amino-terminal Zinc/RING finger motifs. The first TRAFs identified, TRAF1 and TRAF2, were found by virtue of their interactions with the cytoplasmic domain of TNF-receptor 2. The six known TRAFs act as adaptor proteins for a wide range of cell surface receptors and participate in the regulation of cell survival, proliferation, differentiation, and stress responses.TRAF2 is phosphorylated at Ser11 by IKK-ε, promoting K63-linked ubiquitination, NF-κB activation, and cellular transformation.

References

[1] Arch, R.H. et al. (1998) Genes Dev 12, 2821-30.
[2] Chung, J.Y. et al. (2002) J Cell Sci 115, 679-88.
[3] Bradley, J.R. and Pober, J.S. (2001) Oncogene 20, 6482-6491.
[4] Rothe, M. et al. (1994) Cell 78, 681-692.
[5] Shen, R.R. et al. (2012) Mol Cell Biol 32, 4756-4768.

Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb Preparation Products And Raw materials

Raw materials

Preparation Products

Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Universal Biotech Co.,Ltd 15921930842 15921930842 yh-wang@univ-bio.com China 25021 58
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Beijing Dongling Technology Co., Ltd. 13051591126 CHINA 6726 58
Beijing Boning Biotechnology Co., Ltd. 010-67500625 18210120938 384669408@qq.com China 6395 58
Phospho-TRAF2 (Ser11) (E2B6L) Rabbit mAb
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