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ChemicalBook >> CAS DataBase List >>6-NITRO-5-METHYL (1H)INDAZOLE

6-NITRO-5-METHYL (1H)INDAZOLE

CAS No.
72521-00-7
Chemical Name:
6-NITRO-5-METHYL (1H)INDAZOLE
Synonyms
5-Methyl-6-nitroindazole;5-methyl-6-nitro-1H-indazole;6-NITRO-5-METHYL (1H)INDAZOLE;1H-Indazole, 5-methyl-6-nitro-
CBNumber:
CB0789747
Molecular Formula:
C8H7N3O2
Molecular Weight:
177.16
MDL Number:
MFCD09026996
MOL File:
72521-00-7.mol
MSDS File:
SDS
Last updated:2026-05-27 22:54:02
Product description Number Pack Size Price
5-Methyl-6-nitro-1H-indazole >97% OR948085 1g $21
5-Methyl-6-nitro-1H-indazole >97% OR948085 5g $32
5-Methyl-6-nitro-1H-indazole >97% OR948085 25g $126
5-Methyl-6-nitro-1H-indazole >97% OR948085 100g $491
5-Methyl-6-nitro-1H-indazole >97% OR948085 500g $2427
More product size

6-NITRO-5-METHYL (1H)INDAZOLE Properties

Boiling point 379.7±22.0 °C(Predicted)
Density 1.437
storage temp. Sealed in dry,Room Temperature
pka 11.30±0.40(Predicted)
Appearance Light yellow to yellow Solid
InChI InChI=1S/C8H7N3O2/c1-5-2-6-4-9-10-7(6)3-8(5)11(12)13/h2-4H,1H3,(H,9,10)
InChIKey AZWAXIMNWVYSMP-UHFFFAOYSA-N
SMILES N1C2=C(C=C(C)C([N+]([O-])=O)=C2)C=N1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933998090

6-NITRO-5-METHYL (1H)INDAZOLE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR948085 5-Methyl-6-nitro-1H-indazole >97% 72521-00-7 1g $21 2026-06-04 Buy
Apolloscientific OR948085 5-Methyl-6-nitro-1H-indazole >97% 72521-00-7 5g $32 2026-06-04 Buy
Apolloscientific OR948085 5-Methyl-6-nitro-1H-indazole >97% 72521-00-7 25g $126 2026-06-04 Buy
Apolloscientific OR948085 5-Methyl-6-nitro-1H-indazole >97% 72521-00-7 100g $491 2026-06-04 Buy
Apolloscientific OR948085 5-Methyl-6-nitro-1H-indazole >97% 72521-00-7 500g $2427 2026-06-04 Buy
Product number Packaging Price Buy
OR948085 1g $21 Buy
OR948085 5g $32 Buy
OR948085 25g $126 Buy
OR948085 100g $491 Buy
OR948085 500g $2427 Buy

6-NITRO-5-METHYL (1H)INDAZOLE Chemical Properties,Uses,Production

Synthesis

2,4-DIMETHYL-5-NITROANILINE

2124-47-2

6-NITRO-5-METHYL (1H)INDAZOLE

72521-00-7

The general procedure for the synthesis of 5-methyl-6-nitroindazole from 2,4-dimethyl-5-nitroaniline is as follows: 1. 2,4-dimethyl-5-nitroaniline (1.662 g, 10.00 mmol) was dissolved in glacial acetic acid (100 ml) and the mixture was cooled to 0°C. 2. Sodium nitrite solution (1 equiv, 690 mg dissolved in 2 ml of water) was slowly added while keeping the reaction temperature below 25 °C. 3. Stirring of the reaction mixture was continued for 3 hours, followed by filtration. 4. The filtrate was allowed to stand at room temperature for 3 days and then concentrated under reduced pressure. 5. The concentrated residue was diluted with water and the resulting mixture was vigorously stirred. 6. The solid product was collected by filtration, washed thoroughly with cold water and dried. 7. 7. Finally, the product was purified by fast chromatography (dichloromethane/methanol with an eluent ratio of 99:1) to give 1.030 g (58.1% yield) of 5-methyl-6-nitro-1H-indazole in solid form.

References

[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 3, p. 403 - 427
[2] Patent: US2010/160373, 2010, A1. Location in patent: Page/Page column 28-29
[3] Patent: US2011/71143, 2011, A1. Location in patent: Page/Page column 37
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 21, p. 8413 - 8426
[5] Patent: WO2007/95124, 2007, A2. Location in patent: Page/Page column 89-90

6-NITRO-5-METHYL (1H)INDAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 6-NITRO-5-METHYL (1H)INDAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-NITRO-5-METHYL (1H)INDAZOLE pictures 2020-01-13 6-NITRO-5-METHYL (1H)INDAZOLE
72521-00-7
$1.00 1KG 99% 100KG Career Henan Chemical Co

6-NITRO-5-METHYL (1H)INDAZOLE Spectrum

6-NITRO-5-METHYL (1H)INDAZOLE 5-methyl-6-nitro-1H-indazole 5-Methyl-6-nitroindazole 1H-Indazole, 5-methyl-6-nitro- 72521-00-7
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