clofedanol
- CAS No.
- 791-35-5
- Chemical Name:
- clofedanol
- Synonyms
- Dencyl;clofedano;Tussistop;clofedanol;Calmotusin;NSC 113595;Chlofedanol;Clophedianol;CHLOPHENDIANOL;Clophedianol base
- CBNumber:
- CB0875699
- Molecular Formula:
- C17H20ClNO
- Molecular Weight:
- 289.7998
- MDL Number:
- MFCD00866840
- MOL File:
- 791-35-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Chlophedianol-[13C6] ≥98% | 13420 | 1mg | $217 |
| CHLOPHEDIANOL 95.00% | API0009164 | 250MG | $727.65 |
| CHLOPHEDIANOL 95.00% | API0009164 | 1G | $825.3 |
| Melting point | 120° |
|---|---|
| Boiling point | 429.8±45.0 °C(Predicted) |
| Density | 1.148±0.06 g/cm3(Predicted) |
| pka | 13.03±0.29(Predicted) |
| CAS DataBase Reference | 791-35-5 |
| FDA UNII | 42C50P12AP |
| ATC code | R05DB10 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
| Toxicity | LD50 i.v. in mice: 70 mg/kg (Lorenz) |
| REACH Registrations | Active |
clofedanol price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| IsoSciences | 13420 | Chlophedianol-[13C6] ≥98% | 791-35-5 | 1mg | $217 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009164 | CHLOPHEDIANOL 95.00% | 791-35-5 | 250MG | $727.65 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0009164 | CHLOPHEDIANOL 95.00% | 791-35-5 | 1G | $825.3 | 2021-12-16 | Buy |
clofedanol Chemical Properties,Uses,Production
Originator
Detigon,Bayer,W. Germany,1958
Uses
(±)-Chlophedianol is an inhalation eutectic compound, used for treatment of respiratory diseases.Also, used in preparation of Deuterated morphine derivatives useful in treatment of pain or as as antitussive agents with reduced risk of possibility of drug abuse.
Definition
ChEBI: Clofedanol is a diarylmethane that is 2-chlorophenyl(phenyl)methane substituted on the methane carbon by a 2-(dimethylamino)ethyl group. Used in the treatment of dry cough, it suppresses the cough reflex by a direct effect on the cough centre in the medulla of the brain. It has a role as an antitussive. It is a diarylmethane and a tertiary amino compound. It is a conjugate base of a clofedanol(1+).
Manufacturing Process
This compound may be produced by reacting o-chlorobenzophenone with acetonitrile in the presence of sodium amide or another strongly basic condensing agent, to form the nitrile of beta-phenyl-beta-o-chlorophenyl-hydracrylic acid, which is then hydrogenated to yield 1-phenyl-1-o-chlorophenyl-3-aminopropanol-1. The latter intermediate compound is subsequently dimethylated with an agent such as methyl sulfate to provide the desired end product 1-o-chlorophenyl-1-phenyl-3-dimethylaminopropanol.
Therapeutic Function
Antitussive
clofedanol Preparation Products And Raw materials
Raw materials
Preparation Products
clofedanol Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +8617792793228 | 1090@dideu.com | China | 8660 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19956 | 58 |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43414 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39927 | 58 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4496 | 50 | |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10266 | 58 |
View Lastest Price from clofedanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-21 | Clofedanol
791-35-5
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2019-07-14 | clofedanol
791-35-5
|
$8.80 | 1KG | 97%-99% | 100kg | Career Henan Chemical Co |
-
- Clofedanol
791-35-5
- $1520.00-2500.00
- TargetMol Chemicals Inc.
-
- clofedanol
791-35-5
- $8.80
- 97%-99%
- Career Henan Chemical Co
