SULCONAZOLE
- CAS No.
- 61318-90-9
- Chemical Name:
- SULCONAZOLE
- Synonyms
- Sulconazol;Sulconazle;SULCONAZOLE;SULCONAZOLE USP/EP/BP;Sulconazle Impurity 3;1-(2-((4-Chlorobenzyl);-2-(2,4-dichlorophenyl);Uniconazole sulfur nitrate;Quizalofop Impurity 8(Propaquizafop);Sulconazole (base and/or unspecified salts)
- CBNumber:
- CB1102530
- Molecular Formula:
- C18H15Cl3N2S
- Molecular Weight:
- 397.75
- MDL Number:
- MFCD00865585
- MOL File:
- 61318-90-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | AA00E982 | 5mg | $114 |
| 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | AA00E982 | 25mg | $178 |
| 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | AA00E982 | 50mg | $292 |
| 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | AA00E982 | 100mg | $424 |
| 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | AA00E982 | 250mg | $815 |
| Boiling point | 558.2±50.0 °C(Predicted) |
|---|---|
| Density | 1.34±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 6.55±0.12(Predicted) |
| CAS DataBase Reference | 61318-90-9 |
| FDA UNII | 5D9HAA5Q5S |
| ATC code | D01AC09 |
SULCONAZOLE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA00E982 | 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | 61318-90-9 | 5mg | $114 | 2026-05-28 | Buy |
| aablocks | AA00E982 | 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | 61318-90-9 | 25mg | $178 | 2026-05-28 | Buy |
| aablocks | AA00E982 | 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | 61318-90-9 | 50mg | $292 | 2026-05-28 | Buy |
| aablocks | AA00E982 | 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | 61318-90-9 | 100mg | $424 | 2026-05-28 | Buy |
| aablocks | AA00E982 | 1-(2-((4-Chlorobenzyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole 95% | 61318-90-9 | 250mg | $815 | 2026-05-28 | Buy |
SULCONAZOLE Chemical Properties,Uses,Production
Chemical Properties
Crystallization, melting point 130-131.5°C. Sulconazole Nitrate (Sulconazole Nitrate): C18 H15C13N2SHNO3.[61318-91-0]. White crystal or crystalline powder, odorless or slightly odorless. Easily soluble in dimethylformamide, soluble in methanol, slightly soluble in glacial acetic acid, insoluble in ethanol, acetone or chloroform, several insoluble in water. Melting point 130.5～132℃(acetone).
Uses
Sulconazole (Exelderm) is a synthetic, sulfur-substituted imidazole that is structurally related to the other imidazole antifungals (ketoconazole, econazole, and miconazole). It is postulated to inhibit 14-α-demethylase for decreased ergosterol synthesis, increased cell membrane permeability, and resultant cell death. It is active against most dermatophytes, yeast, and P. orbiculare. It also displays activity against some aerobic and anaerobic gram-positive bacteria. Sulconazole is a mild inducer of the cytochrome P-450 microsomal enzymes CYP1A1 and CYP2B1 and could theoretically induce the metabolism of other drugs.
Definition
ChEBI: A member of the class of imidazoles that is 1-ethyl-1H-imidazole in which one of the hydrogens of the methyl group is replaced by a (4-chlorobenzyl)sulfanediyl group while a second is replaced by a 2,4-dichlorophenyl group.
Indications
Topical treatment of mycoses of the skin induced or sustained by fungi such as dermatophytes and yeasts.
Indications
Sulconazole (Exelderm) is a synthetic, sulfur-substituted imidazole that is structurally related to the other imidazole antifungals (ketoconazole, econazole, and miconazole). It is postulated to inhibit 14-α-demethylase for decreased ergosterol synthesis, increased cell membrane permeability, and resultant cell death. It is active against most dermatophytes, yeast, and P. orbiculare. It also displays activity against some aerobic and anaerobic gram-positive bacteria. Sulconazole is a mild inducer of the cytochrome P-450 microsomal enzymes CYP1A1 and CYP2B1 and could theoretically induce the metabolism of other drugs.
Side effects
Local irritations and allergic reactions may occur in rare cases and are mainly due to the galenic formulation.
Synthesis
Sulconazole, 1-[2,4-dichloro-|-[(4-chlorobenzyl)thio]phenethyl]-imidazole (35.2.9), is an analog of exonazole. It differs in the replacement of the etheral oxygen bridge (which connects the 4-chlorobenzyl part of the molecule with phenethylimidazole) for a thioether bond. The corresponding changes in the synthesis of this drug are the replacement of the hydroxyl group in 1-(2,4-dichlorophenyl)-2-(1-imidazolyl)-ethanol (35.2.6) with a chlorine atom using thionyl chloride, followed by a reaction of the resulting chloride with 4-chlorobenzylmercaptane to make sulconazole.
Solubility in organics
1 part in 3,333 (water), 1 part in 100 (ethanol), 1 part in 130 (acetone), 1 part in 333 (chloroform), 1 part in 2000 (dioxan), 1 part in 71 (methanol), 1 part in 286(chloromethane), 1 part in 10 (pyridine), 1 part in 2000 (toluene).
SULCONAZOLE Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
SULCONAZOLE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2994 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29093 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15079 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49895 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19956 | 58 |
Related articles
- Pharmacodynamics of Sulconazole
- Sulconazole has a broad spectrum of antifungal activity in vitro and has been shown to be an effective topical antifungal agen....
- Mar 30，2022
View Lastest Price from SULCONAZOLE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-20 | Sulconazole
61318-90-9
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-11-18 | SULCONAZOLE USP/EP/BP
61318-90-9
|
$1.10 | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
-
- Sulconazole
61318-90-9
- $1520.00-2500.00
- TargetMol Chemicals Inc.
-
- SULCONAZOLE USP/EP/BP
61318-90-9
- $1.10
- 99.9%
- Dideu Industries Group Limited
