(1,2,4)Triazolo(1,5-a)pyrazine
- CAS No.
- 399-66-6
- Chemical Name:
- (1,2,4)Triazolo(1,5-a)pyrazine
- Synonyms
- (1,2,4)Triazolo(1,5-a)pyrazine
- CBNumber:
- CB11236667
- Molecular Formula:
- C5H4N4
- Molecular Weight:
- 120.11
- MDL Number:
- MOL File:
- 399-66-6.mol
| Product description | Number | Pack Size | Price |
| [1,2,4]Triazolo[1,5-a]pyrazine 97% | AS147578 | 1g | $61 |
| [1,2,4]Triazolo[1,5-a]pyrazine 97% | AS147578 | 5g | $228 |
| [1,2,4]Triazolo[1,5-a]pyrazine | 220721 | 5.00g | $901 |
| [1,2,4]Triazolo[1,5-a]pyrazine | 220721 | 25.00g | $2703 |
| [1,2,4]Triazolo[1,5-a]pyrazine >98% | T61381 | 250mg | $65 |
(1,2,4)Triazolo(1,5-a)pyrazine price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS147578 | [1,2,4]Triazolo[1,5-a]pyrazine 97% | 399-66-6 | 1g | $61 | 2026-06-04 | Buy |
| Activate Scientific | AS147578 | [1,2,4]Triazolo[1,5-a]pyrazine 97% | 399-66-6 | 5g | $228 | 2026-06-04 | Buy |
| Matrix Scientific | 220721 | [1,2,4]Triazolo[1,5-a]pyrazine | 399-66-6 | 5.00g | $901 | 2026-05-18 | Buy |
| Matrix Scientific | 220721 | [1,2,4]Triazolo[1,5-a]pyrazine | 399-66-6 | 25.00g | $2703 | 2026-05-18 | Buy |
| Synthonix | T61381 | [1,2,4]Triazolo[1,5-a]pyrazine >98% | 399-66-6 | 250mg | $65 | 2026-05-06 | Buy |
(1,2,4)Triazolo(1,5-a)pyrazine Chemical Properties,Uses,Production
Synthesis
51519-20-1
399-66-6
The general procedure for the synthesis of [1,2,4]triazolo[1,5-a]pyrazines from the compound (CAS:51519-20-1) is as follows: polyphosphoric acid (250 g) was added to (Z)-N'-hydroxy-N-(pyrazin-2-yl)carbamoylamide (25.07 g, 181 mmol), followed by immediately heating the reaction mixture to 90 °C. The reaction mixture was kept stirred at this temperature for 4 hours. After completion of the reaction, the hot reaction mixture was slowly poured into ice water and the pH was adjusted to basic with sodium bicarbonate. Subsequently, the aqueous phase was extracted with dichloromethane (1 L, followed by 3 x 0.5 L). All organic phases were combined and dried with anhydrous sodium sulfate (Na2SO4), after which the organic phase was concentrated. The crude product was purified by batch crystallization from ethanol. A final product of 18.10 g was obtained in 83% yield.
References
[1] Patent: US2008/153843, 2008, A1. Location in patent: Page/Page column 68
(1,2,4)Triazolo(1,5-a)pyrazine Preparation Products And Raw materials
(1,2,4)Triazolo(1,5-a)pyrazine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49945 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Gihi Chemicals Co., Limited | +86-0571-86217390 +8618058761490 | info@gihichem.com | China | 998 | 58 |
| NovoChemy Ltd. | -- | sales@novochemy.com | Germany | 6328 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12740 | 55 | |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. | 02161555100 | China | 820 | 58 | |
| Suzhou Maikaier Biological Medicine Technology Co Ltd. | 15952441622 | 1802461539@qq.mm | China | 102 | 55 |
