ChemicalBook >> CAS DataBase List >>10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one
10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one
![10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one Structure](CAS/GIF/63950-05-0.gif)
- CAS No.
- 63950-05-0
- Chemical Name:
- 10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one
- Synonyms
- 13-Dihydroadriamycin;Doxorubicinol (Mixture of diasteroMers);Doxorubicinol-13C-d3 (Mixture of diasteroMers);Doxorubicinol hydrochloride - Mixture of Diasteromers;Doxorubicinol Hydrochloride (Mixture of diastereomers);Doxorubicinol Hydrochloride (Mixture of diastereomers) Discontinued See: D558021;10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one;Doxorubicinol HydrochlorideQ: What is Doxorubicinol Hydrochloride Q: What is the CAS Number of Doxorubicinol Hydrochloride Q: What is the storage condition of Doxorubicinol Hydrochloride Q: What are the applications of Doxorubicinol Hydrochloride
- CBNumber:
- CB11255424
- Molecular Formula:
- C27H32ClNO11
- Molecular Weight:
- 582
- MDL Number:
- MOL File:
- 63950-05-0.mol
Last updated:2025-04-17 18:22:24
| Product description | Number | Pack Size | Price |
| Doxorubicinol Hydrochloride|(Mixture of diastereomers)| ~90% | 163964 | 2mg | $502 |
| Doxorubicinol hydrochloride - Mixture of Diasteromers | FD71682 | 1mg | $900 |
| Doxorubicinol hydrochloride - Mixture of Diasteromers | FD71682 | 0.5mg | $900 |
| Doxorubicinol hydrochloride - Mixture of Diasteromers | FD71682 | 2mg | $908.6 |
| Doxorubicinol hydrochloride - Mixture of Diasteromers | FD71682 | 5mg | $1687.4 |
10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one Properties
| Melting point | 188-192°C |
|---|---|
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| form | Solid |
| color | Pink to red |
| FDA UNII | 9LVW1H75S7 |
10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 163964 | Doxorubicinol Hydrochloride|(Mixture of diastereomers)| ~90% | 2mg | $502 | 2026-06-03 | Buy | |
| Biosynth | FD71682 | Doxorubicinol hydrochloride - Mixture of Diasteromers | 63950-05-0 | 1mg | $900 | 2026-06-04 | Buy |
| Biosynth | FD71682 | Doxorubicinol hydrochloride - Mixture of Diasteromers | 63950-05-0 | 0.5mg | $900 | 2026-06-04 | Buy |
| Biosynth | FD71682 | Doxorubicinol hydrochloride - Mixture of Diasteromers | 63950-05-0 | 2mg | $908.6 | 2026-06-04 | Buy |
| Biosynth | FD71682 | Doxorubicinol hydrochloride - Mixture of Diasteromers | 63950-05-0 | 5mg | $1687.4 | 2026-06-04 | Buy |
10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one Chemical Properties,Uses,Production
Chemical Properties
Dark Red Solid
Uses
A metabolite of Doxorubicin as neoplasm inhibitor
in vivo
In vivo, in tumor-bearing mice, Nilotinib, acting as ABCB1 inhibitor, is found to increase the accumulation of Doxorubicin and Doxorubicinol hydrochloride in cancer tissues. This implies that weaker anticancer activity of Doxorubicinol hydrochloride may be related to its increased affinity to ABC transporters, thus leading to a lower intracellular concentration of the agent[1].
In comparison with wild-type mice, the terminal half-life and the area under the plasma concentration-time curve of Doxorubicin in mdr1a(-/-) mice are 1.6- and 1.2-fold higher respectively. The retention of both Doxorubicin and its metabolite Doxorubicinol hydrochloride in the hearts of mdr1a(-/-) mice is substantially prolonged[2].
10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one Preparation Products And Raw materials
Raw materials
Preparation Products
10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one Suppliers
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| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
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63950-05-0(10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one)Related Search:
10-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyl-oxan-2-yl]oxy-8-(1,2-dihydro xyethyl)-6,8,11-trihydroxy-1-methoxy-9,10-dihydro-7H-tetracene-5,12-di one
Doxorubicinol Hydrochloride
(Mixture of diastereomers)
Discontinued See: D558021
Doxorubicinol Hydrochloride
(Mixture of diastereomers)
Doxorubicinol (Mixture of diasteroMers)
Doxorubicinol-13C-d3 (Mixture of diasteroMers)
Doxorubicinol hydrochloride - Mixture of Diasteromers
13-Dihydroadriamycin
Doxorubicinol HydrochlorideQ: What is
Doxorubicinol Hydrochloride Q: What is the CAS Number of
Doxorubicinol Hydrochloride Q: What is the storage condition of
Doxorubicinol Hydrochloride Q: What are the applications of
Doxorubicinol Hydrochloride
63950-05-0
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