1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI)
![1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI) Structure](CAS/GIF/194278-45-0.gif)
- CAS No.
- 194278-45-0
- Chemical Name:
- 1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI)
- Synonyms
- 3-Methyl-1H-pyrazolo[4,3-...;3-methyl-2h-pyrazolo[4,3-b]pyridine;1H-Pyrazolo[4,3-b]pyridine, 3-methyl-;1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI)
- CBNumber:
- CB11274524
- Molecular Formula:
- C7H7N3
- Molecular Weight:
- 133.15
- MDL Number:
- MFCD08062968
- MOL File:
- 194278-45-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3-Methyl-1H-pyrazolo[4,3-b]pyridine | UHA27845 | 5g | $295 |
| 3-Methyl-1H-pyrazolo[4,3-b]pyridine 95% | OR904805 | 250mg | $307 |
| 3-Methyl-1H-pyrazolo[4,3-b]pyridine 95% | OR904805 | 1g | $755 |
| 3-Methyl-1H-pyrazolo[4,3-b]pyridine 95% | OR904805 | 250mg | $307 |
| 3-Methyl-1H-pyrazolo[4,3-b]pyridine 95% | OR904805 | 1g | $755 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
| HS Code | 2933998090 |
1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI) price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | UHA27845 | 3-Methyl-1H-pyrazolo[4,3-b]pyridine | 194278-45-0 | 5g | $295 | 2026-06-05 | Buy |
| Apolloscientific | OR904805 | 3-Methyl-1H-pyrazolo[4,3-b]pyridine 95% | 194278-45-0 | 250mg | $307 | 2026-06-04 | Buy |
| Apolloscientific | OR904805 | 3-Methyl-1H-pyrazolo[4,3-b]pyridine 95% | 194278-45-0 | 1g | $755 | 2026-06-04 | Buy |
| Apolloscientific | OR904805 | 3-Methyl-1H-pyrazolo[4,3-b]pyridine 95% | 194278-45-0 | 250mg | $307 | 2026-06-04 | Buy |
| Apolloscientific | OR904805 | 3-Methyl-1H-pyrazolo[4,3-b]pyridine 95% | 194278-45-0 | 1g | $755 | 2026-06-04 | Buy |
1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI) Chemical Properties,Uses,Production
Synthesis
87674-20-2
![1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI)](/CAS/GIF/194278-45-0.gif)
194278-45-0
General procedure for the synthesis of 3-methyl-1H-pyrazolo[4,3-b]pyridine from 2-acetyl-3-fluoropyridine: 1-(3-fluoropyridin-2-yl)ethanone (1.00 g, 7.19 mmol) was dissolved in hydrazine monohydrate (12 mL, 247.00 mmol), which was heated in a microwave reactor for 3 hours at 130 °C. Upon completion of the reaction, water (50 mL) was added to dilute the reaction mixture and extracted with ethyl acetate (3 x 25 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. Purification by a Biotage fast chromatography system (using a SNAP 50g silica gel column with ethyl acetate/ethanol as eluent, with the ratio tapered from 95/5 to 70/30) gave a cream-colored solid product (575 mg, 60% yield). The product was identified by 1H NMR (500 MHz, DMSO-d6): δ 12.87 (broad single peak, 1H), 8.46 (double peak, J = 4.3, 1.4 Hz, 1H), 7.91 (double peak, J = 8.5, 1.4 Hz, 1H), 7.33 (double peak, J = 8.5, 4.3 Hz, 1H), 2.53 (single peak, 3H). 13C NMR (126 MHz, DMSO-d6) δ 144.51, 142.04, 139.94, 133.42, 121.12, 118.49, 11.24. LCMS (Method M) retention time 0.52 min, [M + H]+ 134; HRMS calculated value C7H8N3: 134.0718, measured value: 134.0726.
References
[1] Patent: WO2016/26549, 2016, A1. Location in patent: Page/Page column 68-69
1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI) Preparation Products And Raw materials
1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
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