TETRACHLOROHYDROQUINONE
- CAS No.
- 87-87-6
- Chemical Name:
- TETRACHLOROHYDROQUINONE
- Synonyms
- 2,3,5,6-Tetrachlorohydroquinone;usafdo-62;USAF do-62;nordrosophilina;TETRACHLOROQUINOL;dihydro-p-chloranil;perchlorohydroquinone;Tetrachlorobenzoquinol;etrachlorohydroquinone;tetrachloro-hydroquinon
- CBNumber:
- CB1142800
- Molecular Formula:
- C6H2Cl4O2
- Molecular Weight:
- 247.89
- MDL Number:
- MFCD00041748
- MOL File:
- 87-87-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Tetrachlorohydroquinone >98.0%(GC) | T0067 | 5g | $37 |
| Tetrachlorohydroquinone >98.0%(GC) | T0067 | 25g | $105 |
| Tetrachlorohydroquinone ≥98% | 23231 | 1g | $44 |
| Tetrachlorohydroquinone ≥98% | 23231 | 5g | $110 |
| Tetrachlorohydroquinone ≥98% | 23231 | 10g | $198 |
| Melting point | 238-240 °C |
|---|---|
| Boiling point | 352.31°C (rough estimate) |
| Density | 1.8232 (rough estimate) |
| refractive index | 1.4813 (estimate) |
| storage temp. | Refrigerator |
| solubility | DMSO (Sparingly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 5.54±0.33(Predicted) |
| color | Off-White to Light Orange |
| Water Solubility | 21.5mg/L(temperature not stated) |
| CAS DataBase Reference | 87-87-6(CAS DataBase Reference) |
| FDA UNII | 5P245C48WP |
| EPA Substance Registry System | 2,3,5,6-Tetrachlorohydroquinone (87-87-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312+P330-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-41 | |||||||||
| Safety Statements | 26-36/37/39-39 | |||||||||
| RTECS | MX7700000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2914.79.4000 | |||||||||
| NFPA 704 |
|
TETRACHLOROHYDROQUINONE price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T0067 | Tetrachlorohydroquinone >98.0%(GC) | 87-87-6 | 5g | $37 | 2026-04-30 | Buy |
| TCI Chemical | T0067 | Tetrachlorohydroquinone >98.0%(GC) | 87-87-6 | 25g | $105 | 2026-04-30 | Buy |
| Cayman Chemical | 23231 | Tetrachlorohydroquinone ≥98% | 87-87-6 | 1g | $44 | 2026-04-30 | Buy |
| Cayman Chemical | 23231 | Tetrachlorohydroquinone ≥98% | 87-87-6 | 5g | $110 | 2026-04-30 | Buy |
| Cayman Chemical | 23231 | Tetrachlorohydroquinone ≥98% | 87-87-6 | 10g | $198 | 2026-04-30 | Buy |
TETRACHLOROHYDROQUINONE Chemical Properties,Uses,Production
Description
Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol. It is cytotoxic to RTL-W1 rainbow trout liver cells (EC50 = 1.55 μM in a neutral red assay). TCHQ increases production of reactive oxygen species (ROS), inhibits apoptosis, and induces loss of the mitochondrial membrane potential and necrosis in splenocytes. In vivo, TCHQ induces glutathione (GSH) depletion in mouse liver.
Chemical Properties
LIGHT BEIGE CRYSTALLINE POWDER
Uses
Tetrachlorohydroquinone is a chlorinated hydroquinone compound used as an analytical standard.
Definition
ChEBI: A tetrachlorobenzene that is 1,2,4,5-tetrachlorobenzene in which the hydrogens at positions 3 and 6 are replaced by hydroxy groups.
Purification Methods
Crystallise the quinone from EtOH or AcOH/EtOH. Sublime it at 77o/0.6x10-3mm. The dibenzoyl derivative has m 233o. [Conant & Fieser J Am Chem Soc 45 2207 1923, Rabideau et al. J Am Chem Soc 108 8130 1986, Beilstein 6 H 851, 6 I 417, 6 II 846, 6 III 4436, 6 IV 5775.]
References
[1] CONSTANZE PIETSCH. Cytotoxic effects of pentachlorophenol (PCP) and its metabolite tetrachlorohydroquinone (TCHQ) on liver cells are modulated by antioxidants.[J]. Cell Biology and Toxicology, 2014, 30 4: 233-252. DOI: 10.1007/s10565-014-9283-4
[2] HSIU-MIN CHEN. The pentachlorophenol metabolite tetrachlorohydroquinone induces massive ROS and prolonged p-ERK expression in splenocytes, leading to inhibition of apoptosis and necrotic cell death.[J]. PLoS ONE, 2014: e89483. DOI: 10.1371/journal.pone.0089483
[3] YING-JAN WANG . Induction of glutathione depletion, p53 protein accumulation and cellular transformation by tetrachlorohydroquinone, a toxic metabolite of pentachlorophenol[J]. Chemico-Biological Interactions, 1997, 105 1: Pages 1-16. DOI: 10.1016/s0009-2797(97)00023-9
TETRACHLOROHYDROQUINONE Preparation Products And Raw materials
Raw materials
Preparation Products
TETRACHLOROHYDROQUINONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32468 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9995 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43333 | 58 |
| XIAMEN EQUATION CHEMICAL CO.,LTD | +86-5926515854 +86-18060954864 | sales@equationchemical.com | China | 2999 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
View Lastest Price from TETRACHLOROHYDROQUINONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Tetrachlorohydroquinone
87-87-6
|
$142.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2021-08-12 | TETRACHLOROHYDROQUINONE
87-87-6
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-09-04 | TETRACHLOROHYDROQUINONE
87-87-6
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Tetrachlorohydroquinone
87-87-6
- $142.00
- TargetMol Chemicals Inc.
-
- TETRACHLOROHYDROQUINONE
87-87-6
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- TETRACHLOROHYDROQUINONE
87-87-6
- $1.00
- 99%
- Career Henan Chemical Co
