(S)-3-BOC-AMINO-2-PIPERIDONE
- CAS No.
- 92235-39-7
- Chemical Name:
- (S)-3-BOC-AMINO-2-PIPERIDONE
- Synonyms
- N-Boc L-Orinithine LactaM;(S)-3-BOC-AMINO-2-PIPERIDONE;3-Pyridinol,8-(aminomethyl)-;(S)-3-Boc-aminopiperidin-2-one;(S)-3-(Boc-amino)-2-oxopiperidine;(3S)-2-Oxo-3-(Boc-amino)piperidine;t-Butyl (S)-2-oxopiperidin-3-ylcarbamate;3-tert-butyloxycarbonylamino-2-piperidone;TERT-BUTYL (S)-2-OXOPIPERIDIN-3-YLCABAMATE;(S)-tert-butyl 2-oxopiperidin-3-ylcarbamate
- CBNumber:
- CB1146833
- Molecular Formula:
- C10H18N2O3
- Molecular Weight:
- 214.26
- MDL Number:
- MFCD08166304
- MOL File:
- 92235-39-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | OR913300 | 1g | $35 |
| (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | OR913300 | 5g | $90 |
| (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | OR913300 | 10g | $153 |
| (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | OR913300 | 25g | $278 |
| (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | OR913300 | 100g | $1101 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933399990 |
(S)-3-BOC-AMINO-2-PIPERIDONE price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR913300 | (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | 92235-39-7 | 1g | $35 | 2026-06-04 | Buy |
| Apolloscientific | OR913300 | (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | 92235-39-7 | 5g | $90 | 2026-06-04 | Buy |
| Apolloscientific | OR913300 | (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | 92235-39-7 | 10g | $153 | 2026-06-04 | Buy |
| Apolloscientific | OR913300 | (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | 92235-39-7 | 25g | $278 | 2026-06-04 | Buy |
| Apolloscientific | OR913300 | (3S)-3-Aminopiperidin-2-one, 3-BOC protected 97% | 92235-39-7 | 100g | $1101 | 2026-06-04 | Buy |
(S)-3-BOC-AMINO-2-PIPERIDONE Chemical Properties,Uses,Production
Uses
N-Boc L-Orinithine Lactam is used in the synthesis of Pro-Leu-Gly-NH2 analogs for dopamine receptor modulation.
Synthesis
21887-64-9
92235-39-7
General procedure for the synthesis of tert-butyl (S)-2-piperidone-3-carbamate from (S)-5-amino-2-((tert-butoxycarbonyl)amino)pentanoic acid: 64 g (2.75 mmol) of BOC-L-ORN-OH was dissolved in 275 mL of DMF at 0 °C. To this solution 1.22 g (2.75 mmol) of BOP reagent and 1.16 g (20.0 mmol) of sodium bicarbonate were added. The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to about 5 mL. The concentrated mixture was diluted with 100 mL of water and saturated sodium bicarbonate solution (1:1) and subsequently extracted with three 100 mL portions of ethyl acetate (EtOAc). The organic phases were combined, washed sequentially with 300 mL of water and 300 mL of brine, dried over anhydrous sodium sulfate (Na2SO4), filtered, and concentrated under reduced pressure to afford the target product (S)-tert-butyl (S)-piperidin-2-one-3-carbamate (133) as a colorless solid in 0.37 g (62%) yield. The product was analyzed by silica gel thin layer chromatography (TLC) with an Rf value of 0.55 (unfolding agent: dichloromethane-methanol = 10:1). Nuclear magnetic resonance hydrogen spectra (1H NMR, CDCl3) showed δ 1.32 (s, 9H), 1.45-1.64 (m, 1H), 1.65-1.84 (m, 2H), 2.10-2.30 (m, 1H), 3.15-3.25 (m, 2H), 3.79-4.05 (m, 1H), 5.62 (br s, 1H) and 6.99 (br s, 1H). Nuclear magnetic resonance carbon spectra (13C NMR, CDCl3) showed δ 27.7, 28.2, 36.56, 36.61, 41.5, 51.0, 79.5, 156.0 and 172.3.
References
[1] Journal of Medicinal Chemistry, 1996, vol. 39, # 23, p. 4531 - 4536
[2] Patent: WO2016/118877, 2016, A1. Location in patent: Paragraph 00208
(S)-3-BOC-AMINO-2-PIPERIDONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
View Lastest Price from (S)-3-BOC-AMINO-2-PIPERIDONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2020-01-15 | (S)-3-BOC-AMINO-2-PIPERIDONE
92235-39-7
|
$1.00 | 1g | 99% | 1000KGS | Career Henan Chemical Co |
-
- (S)-3-BOC-AMINO-2-PIPERIDONE
92235-39-7
- $1.00
- 99%
- Career Henan Chemical Co
