3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE
![3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE Structure](CAS/GIF/96901-92-7.gif)
- CAS No.
- 96901-92-7
- Chemical Name:
- 3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE
- Synonyms
- 3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE;8-Azabicyclo[3.2.1]octan-3-amine, 8-(phenylmethyl)-;3-(endo-amino)-8-(phenylmethyl)-8-azabicyclo[3.2.1]octane;8-benzyl-8-azabicyclo[3.2.1]octan-3-amine, Mixture of diastereomers
- CBNumber:
- CB11504050
- Molecular Formula:
- C14H20N2
- Molecular Weight:
- 216.32
- MDL Number:
- MFCD09753144
- MOL File:
- 96901-92-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 8-benzyl-8-azabicyclo[3.2.1]octan-3-amine, Mixture of diastereomers | WDA90192 | 0.5g | $312.7 |
| 8-benzyl-8-azabicyclo[3.2.1]octan-3-amine, Mixture of diastereomers | WDA90192 | 5g | $1239 |
| 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine | AA005SG0 | 50mg | $77 |
| 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine | AA005SG0 | 100mg | $93 |
| 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine | AA005SG0 | 250mg | $117 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H318-H335-H302 |
| Precautionary statements | P280-P305+P351+P338-P310-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
| REACH Registrations | Active |
3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | WDA90192 | 8-benzyl-8-azabicyclo[3.2.1]octan-3-amine, Mixture of diastereomers | 96901-92-7 | 0.5g | $312.7 | 2026-06-05 | Buy |
| Biosynth | WDA90192 | 8-benzyl-8-azabicyclo[3.2.1]octan-3-amine, Mixture of diastereomers | 96901-92-7 | 5g | $1239 | 2026-06-05 | Buy |
| aablocks | AA005SG0 | 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine | 96901-92-7 | 50mg | $77 | 2026-05-28 | Buy |
| aablocks | AA005SG0 | 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine | 96901-92-7 | 100mg | $93 | 2026-05-28 | Buy |
| aablocks | AA005SG0 | 8-Benzyl-8-azabicyclo[3.2.1]octan-3-amine | 96901-92-7 | 250mg | $117 | 2026-05-28 | Buy |
3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE Chemical Properties,Uses,Production
Synthesis
76272-34-9
![3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE](/CAS/GIF/96901-92-7.gif)
96901-92-7
The general procedure for the synthesis of 8-benzyl-8-azabicyclo[3.2.1]octan-3-amine from 8-benzyl-8-azabicyclo[3.2.1]octan-3-one oxime is as follows: these amines are key intermediates in the synthesis of compounds 4 and 20. First, 1-methylpiperazine or piperidine (1 mmol) and triethylamine (1.5 mmol, 0.21 mL) were sequentially added to a solution of 4-nitrobenzyl chloride (1 mmol) in anhydrous THF (3 mL). The reaction mixture was stirred at 70 °C overnight. Upon completion of the reaction, it was separated by extraction with dichloromethane and water. The organic phases were combined, dried over anhydrous Na2SO4 and subsequently concentrated under reduced pressure. The residue was purified by column chromatography (eluent ratio hexane/ethyl acetate 1:4) and the structure was confirmed by 1H NMR (see Supplementary Information). The purified product was dissolved in 10 mL of ethanol and PtO2 (0.01 g) was added under nitrogen protection. The hydrogenation reaction was carried out for 16 h at 50 psi hydrogen pressure using a Parr hydrogenation unit. At the end of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under vacuum to give the target amine compound in quantitative yield.
References
[1] Patent: WO2004/54974, 2004, A2. Location in patent: Page 55
[2] European Journal of Medicinal Chemistry, 2011, vol. 46, # 7, p. 2917 - 2929
[3] Patent: EP1156045, 2001, A1
[4] Patent: EP1243268, 2002, A1
[5] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 18, p. 3994 - 4007
3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE Preparation Products And Raw materials
Raw materials
Preparation Products
3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43414 | 58 |
| BePharm Ltd | 400-685-9117 | market@bepharm.com | China | 15081 | 60 |
| Abydos Scientific | 025-84767922 18936879710 | sales@abydoscientific.com | China | 1000 | 58 |
| Jiangsu aikang biomedical research and development co., LTD | 025-58859352 17714375163 | qzhang@aikonchem.com | China | 15525 | 58 |
| Lingyuan Bebiansen Biological Technology Co., Ltd | 18642120371 | 2837458851@qq.com | China | 7963 | 58 |
| Zhengzhou Converging Chemical Co. LTD | 0371-53399770 18037166334 | 3857571523@qq.com | China | 6593 | 58 |
| Henan Zhuofan Chemical Co. , Ltd. | 15638881523 | 68825546@qq.com | China | 2066 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | 51288865780 | sales@biosynth.com | China | 6051 | 58 |
96901-92-7(3-AMINO-8-BENZYL-8-AZABICYCLO[3.2.1]OCTANE)Related Search:
1of4
