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ChemicalBook >> CAS DataBase List >>ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE

ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE

CAS No.
91252-54-9
Chemical Name:
ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE
Synonyms
-1,2-oxazoL;BUTTPARK 146\06-95;ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE;ethyl 5-tert-butyl-1,2-oxazole-3-carboxylate;5-tert-Butyl-isoxazole-3-carboxylic acid ethyl ester;3-Isoxazolecarboxylic acid, 5-(1,1-dimethylethyl)-, ethyl ester
CBNumber:
CB1225516
Molecular Formula:
C10H15NO3
Molecular Weight:
197.23
MDL Number:
MFCD00085057
MOL File:
91252-54-9.mol
Last updated:2026-05-27 23:15:38
Product description Number Pack Size Price
Ethyl 5-(tert-butyl)isoxazole-3-carboxylate ≥95% OR29684 250mg $24
Ethyl 5-tert-butylisoxazole-3-carboxylate 073369 1.00g $37
Ethyl 5-tert-butylisoxazole-3-carboxylate 073369 5.00g $106
Ethyl 5-(tert-butyl)isoxazole-3-carboxylate >98% E67791 250mg $20
Ethyl 5-(tert-butyl)isoxazole-3-carboxylate >98% E67791 5g $120
More product size

ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE Properties

Boiling point 108-111 °C(Press: 5.5 Torr)
Density 1.057±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka -4.93±0.50(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P260-P280-P312
Hazard Codes  Xi
Hazard Note  Irritant
HS Code  2934999090

ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR29684 Ethyl 5-(tert-butyl)isoxazole-3-carboxylate ≥95% 91252-54-9 250mg $24 2026-06-04 Buy
Matrix Scientific 073369 Ethyl 5-tert-butylisoxazole-3-carboxylate 91252-54-9 1.00g $37 2026-05-18 Buy
Matrix Scientific 073369 Ethyl 5-tert-butylisoxazole-3-carboxylate 91252-54-9 5.00g $106 2026-05-18 Buy
Synthonix E67791 Ethyl 5-(tert-butyl)isoxazole-3-carboxylate >98% 91252-54-9 250mg $20 2026-05-06 Buy
Synthonix E67791 Ethyl 5-(tert-butyl)isoxazole-3-carboxylate >98% 91252-54-9 5g $120 2026-05-06 Buy
Product number Packaging Price Buy
OR29684 250mg $24 Buy
073369 1.00g $37 Buy
073369 5.00g $106 Buy
E67791 250mg $20 Buy
E67791 5g $120 Buy

ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE Chemical Properties,Uses,Production

Synthesis

2-Hexenoic acid, 2-hydroxy-5,5-dimethyl-4-oxo-, ethyl ester

94122-76-6

ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE

91252-54-9

General procedure for the synthesis of ethyl 5-tert-butyl-isoxazole-3-carboxylate from the compound (CAS:94122-76-6): tert-butyl alkenone (50) (6.00 g, 30.0 mmol) was dissolved in anhydrous ethanol/THF (1:1, 70 mL) and stirred at room temperature. To this solution was added hydroxylamine hydrochloride (2.29 g, 33.0 mmol) and the resulting mixture was stirred under nitrogen protection for 12 hours. Subsequently, the mixture was transferred to a Soxhlet extractor fitted with molecular sieves and heated to reflux for 2 hours. After completion of the reaction, the mixture was allowed to cool and the solvent was removed by evaporation. Water (100 mL) was added and the mixture was extracted with dichloromethane (2 x 100 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated. The crude product was purified by silica gel column chromatography to afford ethyl 5-tert-butyl-isoxazole-3-carboxylate (54) as a colorless oil (3 g, 51% yield).1H NMR (500 MHz, CDCl3) data for 54: δ 6.37 (s, 1H), 4.43 (q, 2H), 1.41 (t, 3H), 1.37 (s, 9H).

References

[1] Patent: US2006/199853, 2006, A1. Location in patent: Page/Page column 45
[2] Patent: US2006/223884, 2006, A1. Location in patent: Page/Page column 57-58

13395-36-3
91252-54-9
Synthesis of ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE from ETHYL TRIMETHYLACETOPYRUVATE

ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE Preparation Products And Raw materials

Global( 65)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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Shanghai Longyu Biotechnology Co., Ltd.
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Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co
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Aladdin Scientific
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Amadis Chemical Company Limited
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J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
BeiJing Hwrk Chemicals Limted 0757-86329057 18934348241 sales4.gd@hwrkchemical.com China 14063 55
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10186 62
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29975 65

View Lastest Price from ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 5-(tert-butyl)isoxazole-3-carboxylate pictures 2020-02-06 Ethyl 5-(tert-butyl)isoxazole-3-carboxylate
91252-54-9
$1.00 1KG Min98% HPLC Career Henan Chemical Co
BUTTPARK 146\06-95 ETHYL 5-TERT-BUTYLISOXAZOLE-3-CARBOXYLATE 5-tert-Butyl-isoxazole-3-carboxylic acid ethyl ester 3-Isoxazolecarboxylic acid, 5-(1,1-dimethylethyl)-, ethyl ester -1,2-oxazoL ethyl 5-tert-butyl-1,2-oxazole-3-carboxylate 91252-54-9 Heterocycles series
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